Abstract: The invention provides methods of diagnosing autism spectrum disorders (ASD) by identification of altered metabolic characteristics in such subjects. By measuring concentrations of metabolites in a sample, such as a blood or plasma sample, from a subject, changes in the activity of specific metabolic pathways can be identified. In turn, ASD subjects can be classified based on metabolic defects. Thus, the methods allow healthcare professionals to provide patient-specific guidance on a course of treatment for individuals who have or are at risk of developing ASD.

Abstract: A rotor rim for an electric machine, having at least two solid annular plates and axially oriented tension bolts connecting the annular plates with each other, wherein on the outer circumference of annular plates grooves are arranged for accommodating rotor poles, for each rotor pole at least two tension bolts are provided, between each two adjacent annular plates a layer of intermediate ring elements is arranged, each layer includes exactly one intermediate ring element per rotor pole, intermediate ring elements are arranged such that between each two adjacent intermediate ring elements a ventilation duct is formed which extends from the inside of the rotor rim to the outer circumference of the rotor rim where it opens into space between the rotor poles, and each intermediate ring element is penetrated by at least two tension bolts and only abuts with a part of its axially oriented surface against adjacent annular plates.

Abstract: A bearing arrangement includes two bearing rings which can be rotated with respect to one another about a common axis, an annular module carrier, an encoder, and at least one sensor module. The module carrier is arranged axially on one of the two bearing rings. The encoder is arranged on the other one of the two bearing rings. The at least one sensor module is arranged in the module carrier. In some embodiments, the module carrier has a cut-out on at least one of its axial side surfaces. through which a lubricant can be introduced into the bearing. The cut-out is arranged circumferentially in the region away from the sensor modules. In other embodiments, the module carrier has at least one predetermined break point for configuring a cut-out.

Abstract: A bearing arrangement includes two bearing rings which can be rotated with respect to one another about a common axis, an annular module carrier, an encoder, and at least one sensor module. The module carrier is arranged axially on one of the two bearing rings. The encoder is arranged on the other one of the two bearing rings. The at least one sensor module is arranged in the module carrier. In some embodiments, the module carrier has a cut-out on at least one of its axial side surfaces. through which a lubricant can be introduced into the bearing. The cut-out is arranged circumferentially in the region away from the sensor modules. In other embodiments, the module carrier has at least one predetermined break point for configuring a cut-out.

Abstract: A roller tappet includes a housing, and the housing includes a first housing element and a second housing element. The first housing element has a receiving region configured to receive a roller of the roller tappet, and the second housing element is separate from the first housing element and is forged. The first housing element may be formed from metal sheet.

Abstract: A bearing assembly includes a thermosetting plastic bearing carrier having a receptacle for holding a bearing ring of the bearing and an injection molded connector between an inner circumference of the receptacle and an outer circumference of the bearing ring made from a thermoplastic plastic. The connector may include axial end portions that radially overlap portions of the bearing carrier. Also a method for forming a bearing assembly.

Abstract: A bearing assembly includes a roller bearing connected with a plate-shaped bearing support. The bearing support has a receiving bore for an outer ring of the roller bearing, and the outer ring of the roller bearing is affixed to the bearing support with two affixing plates that are fixed to first and second end sides of the bearing support. The two affixing plates clamp the outer ring at two clamping surfaces. An axial spacing of the first and second end sides of the bearing support is smaller than an axial spacing of the clamping surfaces of the outer ring, and a spring element configured to act in the axial direction is disposed between one of the two affixing plates and the bearing support.

Abstract: A bearing assembly includes a roller bearing connected with a bearing support having a plate-shaped section. The bearing support has a receiving bore for an outer ring of the roller bearing, and the outer ring of the roller bearing is affixed to the bearing support with two affixing plates that are fixed to first and second end sides of the bearing support and that clamp the outer ring at two clamping surfaces. An axial spacing of the first and second end sides of the bearing support is smaller than an axial spacing of the clamping surfaces of the outer ring, and the two affixing plates have a different mechanical strength.

Abstract: A bearing arrangement is disclosed having a bearing and a bearing support. The bearing is coupled to the bearing support at an axial side. The bearing provides first and second bearing rings that define a bearing interior there between. A first groove is formed at the first bearing ring's radial side facing the second bearing ring. A coupling element is arranged at the bearing's axial side facing the bearing support. The coupling element includes a first, preferably nose-shaped, radial protrusion that is in engagement with the first groove, and a second radial protrusion, which at least partially encompasses the bearing support at a side facing away from the bearing, so that the coupling element fastens the bearing to the bearing support. A coupling element for such a bearing arrangement is also provided.

Abstract: A bearing arrangement is disclosed having a bearing and a bearing support. The bearing is coupled to the bearing support at an axial side. The bearing provides first and second bearing rings that define a bearing interior there between. A first groove is formed at the first bearing ring's radial side facing the second bearing ring. A coupling element is arranged at the bearing's axial side facing the bearing support. The coupling element includes a first, preferably nose-shaped, radial protrusion that is in engagement with the first groove, and a second radial protrusion, which at least partially encompasses the bearing support at a side facing away from the bearing, so that the coupling element fastens the bearing to the bearing support. A coupling element for such a bearing arrangement is also provided.

Abstract: A bearing assembly includes a thermosetting plastic bearing carrier having a receptacle for holding a bearing ring of the bearing and an injection molded connector between an inner circumference of the receptacle and an outer circumference of the bearing ring made from a thermoplastic plastic. The connector may include axial end portions that radially overlap portions of the bearing carrier. Also a method for forming a bearing assembly.

Abstract: A bearing assembly includes a roller bearing connected with a bearing support having a plate-shaped section. The bearing support has a receiving bore for an outer ring of the roller bearing, and the outer ring of the roller bearing is affixed to the bearing support with two affixing plates that are fixed to first and second end sides of the bearing support and that clamp the outer ring at two clamping surfaces. An axial spacing of the first and second end sides of the bearing support is smaller than an axial spacing of the clamping surfaces of the outer ring, and the two affixing plates have a different mechanical strength.

Abstract: A bearing assembly includes a roller bearing connected with a plate-shaped bearing support. The bearing support has a receiving bore for an outer ring of the roller bearing, and the outer ring of the roller bearing is affixed to the bearing support with two affixing plates that are fixed to first and second end sides of the bearing support. The two affixing plates clamp the outer ring at two clamping surfaces. An axial spacing of the first and second end sides of the bearing support is smaller than an axial spacing of the clamping surfaces of the outer ring, and a spring element configured to act in the axial direction is disposed between one of the two affixing plates and the bearing support.

Abstract: A roller tappet includes a housing, and the housing includes a first housing element and a second housing element. The first housing element has a receiving region configured to receive a roller of the roller tappet, and the second housing element is separate from the first housing element and is forged. The first housing element may be formed from metal sheet.

Abstract: An unbalanced shaft for compensating inertial forces and/or moments of inertia for a reciprocating internal combustion engine includes at least one shaft section and a bearing journal adjacent to the at least one shaft section and an unbalance mass disposed on the shaft section. The bearing journal is formed from at least two parts including a first solid bearing segment and a second solid bearing segment, and a center of gravity of the shaft section and the bearing journal is eccentric to an axis of rotation of the unbalanced shaft. The first solid bearing segment includes a portion projecting into the second solid bearing segment and the second solid bearing segment include a portion projecting into the first solid bearing segment such that the first and the second solid bearing segment are secured at least axially relative to each other.

Abstract: A system and method of performing percutaneous image guided pericardial procedures is disclosed. The method comprises the steps of: providing a tool tracking system having a display for visualization of virtual representations of tracked tools which is configured to have a field of operation encompassing percutaneous pericardial space access and procedures; providing a patient specific three dimensional model of the patient for use in percutaneous pericardial space procedures that is registered with the tool tracking system for simultaneous display of the model and the virtual representation of the tracked tools on the system display; percutaneously inserting at least one tracked tool for the tool tracking system into the pericardial space; and simultaneously visualizing the virtual representation of the tracked tool and the patient specific model on the system display at least through a portion of a pericardial procedure.

Abstract: A combustor for a turbine engine is provided. The combustor includes a first liner having a first hot side and a first cold side; a second liner having a second hot side and a second cold side, the second hot side and the first hot side forming a combustion chamber therebetween, the combustion chamber configured to receive an air-fuel mixture for combustion therein; and an insert including a body portion extending through the first liner, a shoulder circumscribing the body portion and abutting the first hot side, and an inlet portion coupled to the body portion and abutting the first cold side such that the inlet portion and the shoulder capture the second liner therebetween to retain the insert.

Abstract: A combustor for a turbine engine is provided. The combustor includes a first liner having a first hot side and a first cold side; a second liner having a second hot side and a second cold side, the second hot side and the first hot side forming a combustion chamber therebetween, the combustion chamber configured to receive an air-fuel mixture for combustion therein; and an insert including a body portion extending through the first liner, a shoulder circumscribing the body portion and abutting the first hot side, and an inlet portion coupled to the body portion and abutting the first cold side such that the inlet portion and the shoulder capture the second liner therebetween to retain the insert.