Patents by Inventor Daniel M. Canafax

Daniel M. Canafax has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITIONS AND PHARMACOKINETICS OF A GAMMA-HYDROXYBUTYRIC ACID DERIVATIVE
    Publication number: 20240130996
    Abstract: Pharmaceutical compositions of 4-((L-valyl)oxy)butanoic acid and the pharmacokinetics of 4-((L-valyl)oxy)butanoic acid and ?-hydroxybutyric acid following oral administration of the pharmaceutical compositions to healthy subjects are disclosed.
    Type: Application
    Filed: December 8, 2023
    Publication date: April 25, 2024
    Inventors: WILLIAM W. XIANG, JIA-NING XIANG, DANIEL M. CANAFAX
  • Pharmacokinetics of combined release formulations of a gamma-hydroxybutyric acid derivative
    Patent number: 11944597
    Abstract: Pharmaceutical compositions comprising an immediate release component comprising 4-((L-valyl)oxy)butanoic acid and a modified release component comprising 4-((L-valyl)oxy)butanoic acid and the pharmacokinetics of 4-((L-valyl)oxy)butanoic acid and ?-hydroxybutyrate following oral administration of the pharmaceutical compositions is disclosed.
    Type: Grant
    Filed: October 26, 2022
    Date of Patent: April 2, 2024
    Assignee: XWPHARMA LTD.
    Inventors: Daniel M. Canafax, William W. Xiang, Leonard Blum, Jia-Ning Xiang
  • Modified release compositions of a GAMMA-hydroxybutyric acid derivative
    Patent number: 11925710
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: March 12, 2024
    Assignee: XWPHARMA LTD.
    Inventors: Sami Karaborni, Daniel M. Canafax, Jia-Ning Xiang, William W. Xiang, James Tien, Stefanie Thiel, Norbert Pollinger, Annette Grave
  • Pharmaceutical compositions and pharmacokinetics of a gamma-hydroxybutyric acid derivative
    Patent number: 11896573
    Abstract: Pharmaceutical compositions of 4-((L-valyl)oxy)butanoic acid and the pharmacokinetics of 4-((L-valyl)oxy)butanoic acid and ?-hydroxybutyric acid following oral administration of the pharmaceutical compositions to healthy subjects are disclosed.
    Type: Grant
    Filed: July 22, 2021
    Date of Patent: February 13, 2024
    Assignee: XWPHARMA LTD.
    Inventors: William W. Xiang, Jia-Ning Xiang, Daniel M. Canafax
  • PHARMACEUTICAL COMPOSITIONS AND ORAL DOSAGE FORMS OF KETAMINE DERIVATIVES
    Publication number: 20230285325
    Abstract: Pharmaceutical compositions of ketamine derivatives and oral dosage forms comprising the pharmaceutical compositions are disclosed. Solid oral dosage forms prepared from the pharmaceutical compositions exhibit a zero-order release profile.
    Type: Application
    Filed: May 17, 2023
    Publication date: September 14, 2023
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, WILLIAM W. XIANG, JIA-NING XIANG
  • Pharmaceutical compositions and oral dosage forms of ketamine derivatives
    Patent number: 11690811
    Abstract: Pharmaceutical compositions of ketamine derivatives and oral dosage forms comprising the pharmaceutical compositions are disclosed. Solid oral dosage forms prepared from the pharmaceutical compositions exhibit a zero-order release profile.
    Type: Grant
    Filed: August 12, 2022
    Date of Patent: July 4, 2023
    Assignee: XWPHARMA LTD.
    Inventors: Sami Karaborni, Daniel M. Canafax, William W. Xiang, Jia-Ning Xiang
  • PHARMACEUTICAL COMPOSITIONS AND ORAL DOSAGE FORMS OF KETAMINE DERIVATIVES
    Publication number: 20230098084
    Abstract: Pharmaceutical compositions of ketamine derivatives and oral dosage forms comprising the pharmaceutical compositions are disclosed. Solid oral dosage forms prepared from the pharmaceutical compositions exhibit a zero-order release profile.
    Type: Application
    Filed: August 12, 2022
    Publication date: March 30, 2023
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, WILLIAM W. XIANG, JIA-NING XIANG
  • PHARMACOKINETICS OF COMBINED RELEASE FORMULATIONS OF A GAMMA-HYDROXYBUTYRIC ACID DERIVATIVE
    Publication number: 20230067371
    Abstract: Pharmaceutical compositions comprising an immediate release component comprising 4-((L-valyl)oxy)butanoic acid and a modified release component comprising 4-((L-valyl)oxy)butanoic acid and the pharmacokinetics of 4-((L-valyl)oxy)butanoic acid and ?-hydroxybutyrate following oral administration of the pharmaceutical compositions is disclosed.
    Type: Application
    Filed: October 26, 2022
    Publication date: March 2, 2023
    Inventors: DANIEL M. CANAFAX, WILLIAM W. XIANG, LEONARD BLUM, JIA-NING XIANG
  • Pharmacokinetics of combined release formulations of a ?-hydroxybutyric acid derivative
    Patent number: 11510892
    Abstract: Pharmaceutical compositions comprising an immediate release component comprising 4-((L-valyl)oxy)butanoic acid and a modified release component comprising 4-((L-valyl)oxy)butanoic acid and the pharmacokinetics of 4-((L-valyl)oxy)butanoic acid and ?-hydroxybutyrate following oral administration of the pharmaceutical compositions is disclosed.
    Type: Grant
    Filed: March 18, 2022
    Date of Patent: November 29, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Daniel M. Canafax, William W. Xiang, Leonard Blum, Jia-Ning Xiang
  • MODIFIED RELEASE COMPOSITIONS OF A GAMMA-HYDROXYBUTYRIC ACID DERIVATIVE
    Publication number: 20220323365
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: June 17, 2022
    Publication date: October 13, 2022
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN, STEFANIE THIEL, NORBERT POLLINGER, ANNETTE GRAVE
  • PHARMACEUTICAL GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20220323366
    Abstract: Granulations with granules having a high loading of an active pharmaceutical ingredient are disclosed. The active pharmaceutical ingredient has a high aqueous water solubility. The granules have a narrow particle size distribution and a smooth exterior surface.
    Type: Application
    Filed: May 5, 2022
    Publication date: October 13, 2022
    Inventors: Sami KARABORNI, William W. XIANG, Daniel M. CANAFAX, Jia-Ning XIANG
  • PHARMACOKINETICS OF COMBINED RELEASE FORMULATIONS OF A GAMMA-HYDROXYBUTYRIC ACID DERIVATIVE
    Publication number: 20220304969
    Abstract: Pharmaceutical compositions comprising an immediate release component comprising 4-((L-valyl)oxy)butanoic acid and a modified release component comprising 4-((L-valyl)oxy)butanoic acid and the pharmacokinetics of 4-((L-valyl)oxy)butanoic acid and ?-hydroxybutyrate following oral administration of the pharmaceutical compositions is disclosed.
    Type: Application
    Filed: March 18, 2022
    Publication date: September 29, 2022
    Inventors: DANIEL M. CANAFAX, WILLIAM W. XIANG, LEONARD BLUM, JIA-NING XIANG
  • Modified release compositions of a gamma-hydroxybutyric acid derivative
    Patent number: 11395801
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Grant
    Filed: October 5, 2021
    Date of Patent: July 26, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Sami Karaborni, Daniel M. Canafax, Jia-Ning Xiang, William W. Xiang, James Tien, Stefanie Thiel, Norbert Pollinger, Annette Grave
  • CONTROLLED RELEASE GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20220183977
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing a water-soluble active pharmaceutical ingredient are disclosed. The functional coating provides for immediate release or controlled release of the active pharmaceutical ingredient. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: March 4, 2022
    Publication date: June 16, 2022
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN, NICOLAS D. KIRKLAND
  • Pharmaceutical granulations of water-soluble active pharmaceutical ingredients
    Patent number: 11357734
    Abstract: Granulations with granules having a high loading of an active pharmaceutical ingredient are disclosed. The active pharmaceutical ingredient has a high aqueous water solubility. The granules have a narrow particle size distribution and a smooth exterior surface.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: June 14, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Sami Karaborni, William W. Xiang, Daniel M. Canafax, Jia-Ning Xiang
  • Controlled release granulations of water-soluble active pharmaceutical ingredients
    Patent number: 11304906
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing a water-soluble active pharmaceutical ingredient are disclosed. The functional coating provides for immediate release or controlled release of the active pharmaceutical ingredient. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Grant
    Filed: June 17, 2021
    Date of Patent: April 19, 2022
    Assignee: XWPHARMA LTD.
    Inventors: Sami Karaborni, Daniel M. Canafax, Jia-Ning Xiang, William W. Xiang, James Tien, Nicolas D. Kirkland
  • MODIFIED RELEASE COMPOSITIONS OF A GAMMA-HYDROXYBUTYRIC ACID DERIVATIVE
    Publication number: 20220105044
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing 4-((L-valyl)oxy)butanoic acid are disclosed. The functional coatings provide for immediate release or modified release of 4-((L-valyl)oxy)butanoic acid. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: October 5, 2021
    Publication date: April 7, 2022
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN, STEFANIE THIEL, NORBERT POLLINGER, ANNETTE GRAVE
  • PHARMACEUTICAL COMPOSITIONS AND PHARMACOKINETICS OF A GAMMA-HYDROXYBUTYRIC ACID DERIVATIVE
    Publication number: 20220023247
    Abstract: Pharmaceutical compositions of 4-((L-valyl)oxy)butanoic acid and the pharmacokinetics of 4-((L-valyl)oxy)butanoic acid and ?-hydroxybutyric acid following oral administration of the pharmaceutical compositions to healthy subjects are disclosed.
    Type: Application
    Filed: July 22, 2021
    Publication date: January 27, 2022
    Inventors: WILLIAM W. XIANG, JIA-NING XIANG, DANIEL M. CANAFAX
  • CONTROLLED RELEASE GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20210393529
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing a water-soluble active pharmaceutical ingredient are disclosed. The functional coating provides for immediate release or controlled release of the active pharmaceutical ingredient. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: June 17, 2021
    Publication date: December 23, 2021
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN
  • PHARMACEUTICAL GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20210393537
    Abstract: Granulations with granules having a high loading of an active pharmaceutical ingredient are disclosed. The active pharmaceutical ingredient has a high aqueous water solubility. The granules have a narrow particle size distribution and a smooth exterior surface.
    Type: Application
    Filed: June 17, 2021
    Publication date: December 23, 2021
    Inventors: Sami KARABORNI, William W. XIANG, Daniel M. CANAFAX, Jia-Ning XIANG