Patents by Inventor Daniel M. Freed

Daniel M. Freed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETED TREATMENT OF CANCERS WITH DYSREGULATED FIBROBLAST GROWTH FACTOR RECEPTOR SIGNALING
    Publication number: 20220241275
    Abstract: The present invention provides advantageous methods and compositions for treating a host having a cancer with dysregulation of the FGFR signaling pathway, which includes administering an effective amount of a selective CDK4/6 inhibitor described herein in combination or alternation with a fibroblast growth factor receptor inhibitor.
    Type: Application
    Filed: April 11, 2022
    Publication date: August 4, 2022
    Inventors: Jay Copeland Strum, Chloe Whitworth, Daniel M. Freed
  • TREATMENT OF CANCERS HAVING DRIVING ONCOGENIC MUTATIONS
    Publication number: 20210030758
    Abstract: Methods and compositions are described to treat a cancer having a specific oncogenic driving mutation by administering a CDK4/6 inhibitor in combination with an additional kinase inhibitor, wherein the specific combination provides advantageous or synergistic inhibitory activity, delays acquired resistance to the additional kinase inhibitor, and/or extends the efficacy of the kinase inhibitor.
    Type: Application
    Filed: October 9, 2020
    Publication date: February 4, 2021
    Applicant: G1 Therapeutics, Inc.
    Inventors: Jay Copeland Strum, Daniel M. Freed, Jessica A. Sorrentino, John E. Bisi, Andrew Beelen, Patrick Joseph Roberts