Abstract: Systems and methods are disclosed that provide smart alerts to users, e.g., alerts to users about diabetic states that are only provided when it makes sense to do so, e.g., when the system can predict or estimate that the user is not already cognitively aware of their current condition, e.g., particularly where the current condition is a diabetic state warranting attention. In this way, the alert or alarm is personalized and made particularly effective for that user. Such systems and methods still alert the user when action is necessary, e.g., a bolus or temporary basal rate change, or provide a response to a missed bolus or a need for correction, but do not alert when action is unnecessary, e.g., if the user is already estimated or predicted to be cognitively aware of the diabetic state warranting attention, or if corrective action was already taken.

Abstract: Disclosed is an aerosol generating device comprising a cartridge containing a propellant. When ignited, propellant gases expand through a diffuser, then through and into a clearing pad and then through and into a filler area, thereby de-agglomerating and fluidizing the filler and increasing pressure until a frangible end seal on the retainer end of the cartridge ruptures and releases the filler as an aerosol cloud. Methods for disseminating an aerosol and for using the device are also disclosed.