Patents by Inventor Daniel M. Rotroff

Daniel M. Rotroff has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IDENTIFYING PATIENTS FOR INTENSIVE HYPERGLYCEMIA MANAGEMENT
    Publication number: 20250087318
    Abstract: Systems and methods are provided for assigning a treatment to a patient is provided. A set of genetic data representing a patient. A polygenic score representing the likelihood that a patient will benefit from intensive glycemia treatment is generated from the set of genetic data.
    Type: Application
    Filed: November 22, 2024
    Publication date: March 13, 2025
    Inventors: Daniel M. Rotroff, Kevin M. Pantalone, Galen Miller-Atkins, Arshiya Mariam
  • Identifying patients for intensive hyperglycemia management
    Patent number: 12205686
    Abstract: Systems and methods are provided for assigning a treatment to a patient is provided. A set of genetic data representing a patient. A polygenic score representing the likelihood that a patient will benefit from intensive glycemia treatment is generated from the set of genetic data. A parameter representing a response of the patient to intensive glycemia treatment is assigned according to the polygenic score.
    Type: Grant
    Filed: February 27, 2021
    Date of Patent: January 21, 2025
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Daniel M. Rotroff, Kevin M. Pantalone, Galen Miller-Atkins, Arshiya Mariam
  • NON-INVASIVE METHOD FOR DIAGNOSING CHRONIC LIVER DISEASE AND PRIMARY AND SECONDARY LIVER CANCERS
    Publication number: 20220095949
    Abstract: A method for diagnosing a subject with one or more of hepatocellular carcinoma (HCC), chronic liver disease, colorectal liver metastases (CRLM), and pulmonary hypertension is described. The method includes obtaining a breath sample from a subject, analyzing the breath sample obtained from the subject to determine one or more breath metabolite abundance values, inputting one or more of the breath metabolite abundance values into a machine-learning-model, and assigning a clinical parameter to the subject representing the likelihood that the subject has one or more of HCC, chronic liver disease, CRLM, and pulmonary hypertension.
    Type: Application
    Filed: February 6, 2020
    Publication date: March 31, 2022
    Inventors: Daniela S. Allende, Federico N. Aucejo, Daniel M. Rotroff
  • IDENTIFYING PATIENTS FOR INTENSIVE HYPERGLYCEMIA MANAGEMENT
    Publication number: 20210272661
    Abstract: Systems and methods are provided for assigning a treatment to a patient is provided. A set of genetic data representing a patient. A polygenic score representing the likelihood that a patient will benefit from intensive glycemia treatment is generated from the set of genetic data.
    Type: Application
    Filed: February 27, 2021
    Publication date: September 2, 2021
    Inventors: Daniel M. Rotroff, Kevin M. Pantalone, Galen Miller-Atkins, Arshiya Mariam