Abstract: The present invention provides polypeptide modulators of complement activity, including cyclic polypeptide modulators. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: An optical connector assembly includes first and second optical ferrules. Each of the first and second optical ferrules includes a front portion extending forwardly from a rear portion. The rear portion includes a top side and a bottom side. The bottom side of the rear portion defines a recessed portion. The first and second optical ferrules mate with each other such that the front portion of each of the first and second ferrules is disposed in the recessed portion of the other one of the first and second ferrules. Discrete retainers are assembled to opposite ends of the mated first and second ferrules. Each of the retainers defines a resilient portion resiliently forcing the front portion of one of the first and second mated ferrules against the other one of the first and second optical ferrules.

Abstract: The present method and system provides for recognizing user intent and updating a graphical user interface. In an example, the method and system comprise collecting usage data from users, grouping users based on usage data, assigning a user intent to each group of users, training an intent prediction model using machine learning, providing access to the intent prediction model, assigning an intent to a new user using the intent prediction model, and, modifying the graphical user interface to facilitate the assigned intent of the user.

Abstract: The present invention provides modulators of complement activity. Also provided are methods of utilizing such modulators as therapeutics.

Abstract: A child stroller apparatus includes a rear and a front leg frame respectively having a first and a second side segment, a handle frame having a grip portion and a third side segment respectively connected fixedly with a first and a second joining part that are pivotally connected with each other, a latching mechanism for locking the rear and front leg frames and the handle frame in an unfolded state, and a latch carried with the third side segment. The latch can engage and disengage the first joining part to lock and unlock the grip portion relative to the third side segment. Moreover, a linking part couples the latch to the rear leg frame or the front leg frame so that a folding rotation of the handle frame relative to the rear leg frame causes the latch to disengage from the first joining part.

Abstract: A leasing AI platform receives a message pertaining to leasing a real estate unit, generates a token matrix representing at least a portion of the message, and provide the token matrix as an input to a trained machine learning model. An output of the trained machine learning model comprises an indication of a first category associated with the at least the portion of the message. The leasing AI platform identifies one or more actions associated with the first category, the actions pertaining to leasing the real estate unit, and automatically executes the one or more actions without human involvement in response to receiving the message.

Abstract: New and/or improved coatings, layers or treatments for porous substrates, including battery separators or separator membranes, and/or coated or treated porous substrates, including coated battery separators, and/or batteries or cells including such coatings or coated separators, and/or related methods including methods of manufacture and/or of use thereof are disclosed. Also, new or improved coatings for porous substrates, including battery separators, which comprise at least a matrix material or a polymeric binder, and heat-resistant particles with additional additives, materials or components, and/or to new or improved coated or treated porous substrates, including battery separators, where the coating comprises at least a matrix material or a polymeric binder, and heat-resistant particles with additional additives, materials or components are disclosed.

Abstract: In some implementations, the disclosed systems and methods can detect an interaction with respect to a set of virtual objects, which can start with a particular gesture, and take an action with respect to one or more virtual objects based on a further interaction (e.g., holding the gesture for a particular amount of time, moving the gesture in a particular direction, releasing the gesture, etc.). In some implementations, the disclosed systems and methods can automatically review a 3D video to determine a depicted user or avatar movement pattern (e.g., dance moves, repair procedure, playing an instrument, etc.). In some implementations, the disclosed systems and methods can allow the gesture to included a flat hand with the user's thumb next to the palm, with the gesture toward the user's face.

Abstract: A device for accommodating and magnetizing a tissue-penetrating medical device of various lengths, with or without a cover covering a portion or the entirety of the tissue-penetrating medical device, is disclosed including a sleeve member having an open proximal end, a distal end, an inner surface, an outer surface having a graduated injection depth gauge to indicate needle penetration depth when the cover is placed into a magnetizer, and a hollow body extending between the proximal end and the distal end to form a protective closure over a shaft of a tissue-penetrating medical device. A device having one or more magnetizing elements sectioned into a plurality of movable segments pivoting around an axis to accommodate needles with different lengths is also disclosed. Also disclosed is a device having one or more magnetizing means mounted on a movable element to magnetize needles of various lengths.

Abstract: Techniques are disclosed for allowing remote participation in collaborative video review based on joint state data, for a video collaboration session, maintained by a video collaboration service. A user at a participant client device may provide one or more annotations, such as a drawing annotation, for the video data via a client application. The client application transmits computer-readable instructions for re-creating the drawing annotation to the service, which distributes the drawing instructions to the other participant client devices. Using the drawing instructions, the client applications at the client devices are configured to re-create the drawing annotation on the associated video frame displayed at the client devices. The joint state data communicated to client devices for a given session may include co-presence data that efficiently increases communication among the participants in a session.

Abstract: Multi-stage distributed beamforming for distributed mosaic wireless networks is provided. Embodiments described herein present systems, devices, and methods that provide increased range, data rate, and robustness to interference and jamming. A distributed mosaic wireless network includes a transmitter, a receiver, and one or more distributed clusters of radios referred to herein as mosaics or relay mosaics. Each mosaic consists of several distributed, cooperative radio transceivers (e.g., mosaic nodes) that relay a signal sent by the transmitter towards the receiver. In some embodiments, a single-stage beamforming technique is implemented whereby the transmitter sends a signal to a first mosaic, which then relays this signal by beamforming to the receiver. In some embodiments, a multi-stage beamforming technique is implemented whereby the transmitter sends a signal to a first mosaic, which then relays this signal by beamforming to a second mosaic, which then relays this signal by beamforming to the receiver.

Abstract: Examples described herein relate to offload reliable transport management to a network interface device and store packets to be resent, based on received packet receipt acknowledgements (ACKs), into one or more kernel space queues that are also accessible in user space.

Abstract: Disclosed herein are pyrazole pyrimidine compounds that modulate and/or inhibit hematopoietic progenitor kinase 1, as well as methods of making such compounds and therapeutic methods of using same.

Abstract: An adjustable reusable packaging crate includes four side panels wherein the side panels contain a floating handle mechanism and a floor panel wherein the floor panel contains pegs that lock into an associated center grid lock panel. The adjustable reusable packaging crate is configured to allow adjustment between two size dimensions (e.g., 12 inches×8 inches×10.25 inches versus 17 inches×11 inches by 10.25 inches). In addition, the adjustable reusable packaging crate is configured to break down into a flat generally planar state for easy storage when empty, with no detachable parts.

Abstract: The present method and system are for providing a graphical user interface using machine learning and movement of the user or user device. In an example, the method and system comprise, training a context analyzer machine learning model with training motion data for a training activity context, the context analyzer for predicting a predicted activity context from new motion data; training a response analyzer machine learning model with training usage data and training user responses for the training activity context for a user interface, the response analyzer for predicting the predicted user response from the predicted activity context and new usage data; predicting the predicted user response from motion data and usage data using both the context analyzer and the response analyzer; and determining a preferred variation for the user interface using a predetermined performance metric and the predicted user response.

Abstract: An on-line thickness gauge (OLTG) and method are described herein that are capable of measuring a thickness of a moving glass substrate. In the preferred embodiment, the OLTG includes a Y-guide and a stabilizing unit that respectively captures and stabilizes the moving glass substrate. The OLTG also includes a laser instrument which contains a laser source and a detector. The laser source emits a beam at the front surface of the moving glass substrate. And, the detector receives two beams one of which was reflected by the front surface of the moving glass substrate and the other beam which was reflected by the back surface of the moving glass substrate. The OLTG further includes a processor that analyzes the two beams received by the detector to determine a distance between the two beams which is then used to determine the thickness of the moving glass substrate.