Patents by Inventor Daniel MADDOX

Daniel MADDOX has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SPIROCYCLOHEXANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS ANTI-APOPTOTIC INHIBITORS
    Publication number: 20260001846
    Abstract: Compounds of Formula (I): wherein R1, R2, R3, R4 and are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.
    Type: Application
    Filed: July 7, 2023
    Publication date: January 1, 2026
    Inventors: Annamária BALASSA, Márton CSÉKEI, Ágota ECKER, Rita GARAMVÖLGYI, András KOTSCHY, Gaëtane LE TOUMELIN-BRAIZAT, Zoltán MADARÁSZ, Ágnes PROSZENYÁK, Szabolcs SIPOS, Zoltán SZABÓ, Márton ZWILLINGER, Simon BEDFORD, I-Jen CHEN, James Edward Paul DAVIDSON, Daniel MADDOX, Sean Martin MCKENNA, James Brooke MURRAY, Rachel Jane PARSONS, Stephen STOKES, Claire Louise WALMSLEY
  • 5-[7-(3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBONYL)-1,2,3,4 TETRAHYDROISOQUINOLIN-6-YL]-1H-PYRROLE-3-CARBOXAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS
    Publication number: 20250179047
    Abstract: A compound of formula (I): wherein R3, R4, R5, R6, Z1, Z2 and T are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.
    Type: Application
    Filed: February 23, 2023
    Publication date: June 5, 2025
    Inventors: Annamária BALASSA, Paul Andrew BROUGH, Audrey CLAPERON, Didier DEMARLES, Imre FEJES, Eszter FÖRDÖS, Balázs KOMJÁTI, Daniel MADDOX, Balázs MOLNÁR, James Brooke MURRAY, Stuart RAY, Francesca ROCCHETTI, Emma SANDERS, Melinda SIPOS, Zoltán SIPOS, Zoltán SZLÁVIK, Claire Louise WALMSLEY, Yikang WANG
  • NOVEL CYCLOPROPYL COMPOUNDS
    Publication number: 20240336571
    Abstract: The invention provides new heterocyclic compounds having the general formula (I?), or a solvate or a pharmaceutically acceptable salt thereof: wherein R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
    Type: Application
    Filed: June 21, 2024
    Publication date: October 10, 2024
    Inventors: Mark CHAPMAN, Nicholas Gareth Morse DAVIES, Aaron GERLACH, Christopher John GRAHAM, Sylvain LEBRETON, Ronghua LI, Nina MA, Daniel MADDOX, Ingrid MECHIN, David MOWREY, Karthigeyan NAGARAJAN, Anil NAIR, Roger David NORCROSS, Roger Lluis REDONDO PENA, Alena SAFAROVA, Martin SMRCINA
  • Indole and pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them
    Patent number: 10662173
    Abstract: Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T and W are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.
    Type: Grant
    Filed: August 14, 2017
    Date of Patent: May 26, 2020
    Assignees: LES LABORATOIRES SERVIER, VERNALIS (R&D) LTD
    Inventors: Patrick Casara, Thierry Le Diguarher, Jean-Michel Henlin, Jérôme-Benoît Starck, Arnaud Le Tiran, Guillaume De Nanteuil, Olivier Geneste, James Edward Paul Davidson, James Brooke Murray, I-Jen Chen, Claire Walmsley, Christopher John Graham, Stuart Ray, Daniel Maddox, Simon Bedford
  • INDOLE AND PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20170342051
    Abstract: Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T and W are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring a pro-apoptotic agent.
    Type: Application
    Filed: August 14, 2017
    Publication date: November 30, 2017
    Inventors: Patrick CASARA, Thierry Le Diguarher, Jean-Michel Henlin, Jérôme-Benoît Starck, Arnaud Le Tiran, Guillaume De Nanteuil, Olivier Geneste, James Edward Paul Davidson, James Brooke Murray, I-Jen Chen, Claire Walmsley, Christopher John Graham, Stuart Ray, Daniel Maddox, Simon Bedford
  • Indole and pyrrole compounds, a process for their preparation and pharmaceutical compositions containing them
    Patent number: 9765056
    Abstract: Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T and W are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
    Type: Grant
    Filed: July 22, 2014
    Date of Patent: September 19, 2017
    Assignees: LES LABORATOIRES SERVIER, VERNALIS (R&D) LTD
    Inventors: Patrick Casara, Thierry Le Diguarher, Jean-Michel Henlin, Jéröme-Benoit Starck, Arnaud Le Tiran, Guillaume De Nanteuil, Olivier Geneste, James Edward Paul Davidson, James Brooke Murray, I-Jen Chen, Claire Walmsley, Christopher John Graham, Stuart Ray, Daniel Maddox, Simon Bedford
  • INDOLE AND PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
    Publication number: 20160152599
    Abstract: Compounds of formula (I): wherein Ra, Rb, Rc, Rd, R3, R4, R5, A1, A2, T and W are as defined in the description. Medicinal products containing the same which are useful in treating pathologies involving a deficit in apoptosis, such as cancer, auto-immune diseases, and diseases of the immune system.
    Type: Application
    Filed: July 22, 2014
    Publication date: June 2, 2016
    Applicants: Les Laboratoires Servier, Vernails (R&D) Limited
    Inventors: Patrick CASARA, Thierry LE DIGUARHER, Jean-Michel HENLIN, Jéröme-Benoit STARCK, Arnaud LE TIRAN, Guillaume DE NANTEUIL, Olivier GENESTE, James Edward Paul DAVIDSON, James Brooke MURRAY, I-Jen CHEN, Claire WALMSLEY, Christopher John GRAHAM, Stuart RAY, Daniel MADDOX, Simon BEDFORD