Patents by Inventor Daniel McManus

Daniel McManus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for treating cancer using IAP antisense oligomer and chemotherapeutic agent
    Patent number: 8012944
    Abstract: The invention features methods, compositions, and kits for treating a patient having a proliferative disease.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: September 6, 2011
    Assignee: Pharmascience Inc.
    Inventors: Eric LaCasse, Daniel McManus, Jon P. Durkin
  • Antisense IAP nucleobase oligomers and uses thereof
    Patent number: 7638620
    Abstract: The present invention features nucleobase oligomers that hybridize to IAP polynucleotides, and methods for using them to enhance apoptosis and treat proliferative diseases.
    Type: Grant
    Filed: June 8, 2006
    Date of Patent: December 29, 2009
    Assignee: Aegera Therapeutics, Inc.
    Inventors: Eric LaCasse, Daniel McManus, Jonathan P. Durkin
  • Antisense IAP nucleobase oligomers and uses thereof
    Patent number: 7638497
    Abstract: The present invention features nucleobase oligomers that hybridize to IAP polynucleotide, and methods for using them to enhance apoptosis and treat proliferative disorders.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: December 29, 2009
    Assignee: Aegera Therapeutics, Inc.
    Inventors: Eric LaCasse, Daniel McManus, Jon P. Durkin
  • Antisense IAP nucleobase oligomers and uses thereof
    Publication number: 20070178064
    Abstract: The present invention features nucleobase oligomers that hybridize to IAP polynucleotides, and methods for using them to enhance apoptosis and treat proliferative diseases.
    Type: Application
    Filed: June 8, 2006
    Publication date: August 2, 2007
    Inventors: Eric LaCasse, Daniel McManus, Jonathan Durkin
  • Antisense IAP nucleobase oligomers and uses thereof
    Publication number: 20070135371
    Abstract: The present invention features nucleobase oligomers that hybridize to IAP polynucleotides, and methods for using them to enhance apoptosis.
    Type: Application
    Filed: October 26, 2006
    Publication date: June 14, 2007
    Inventors: Eric LaCasse, Daniel McManus, Jon Durkin, Robert Korneluk, Martin Holcik
  • Antisense IAP nucleobase oligomers and uses thereof
    Publication number: 20070049544
    Abstract: The present invention features nucleobase oligomers that hybridize to IAP polynucleotide, and methods for using them to enhance apoptosis and treat proliferative disorders.
    Type: Application
    Filed: June 30, 2006
    Publication date: March 1, 2007
    Inventors: Eric LaCasse, Daniel McManus, Jon Durkin
  • Antisense IAP nucleobase oligomers and uses thereof
    Publication number: 20070032445
    Abstract: The present invention features nucleobase oligomers that hybridize to IAP polynuclotides, and methods for using them to enhance apoptosis and treat proliferative diseases.
    Type: Application
    Filed: May 30, 2006
    Publication date: February 8, 2007
    Inventors: Eric LaCasse, Daniel McManus, Jon Durkin
  • Antisense IAP nucleobase oligomers and uses thereof
    Patent number: 7091333
    Abstract: The present invention features nucleobase oligomers that hybridize to IAP polynucleotides, and methods for using them to enhance apoptosis and treat proliferative diseases.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: August 15, 2006
    Assignee: Aegera Therapeutics, Inc.
    Inventors: Eric LaCasse, Daniel McManus, Jon P. Durkin
  • IAP nucleobase oligomers and oligomeric complexes and uses thereof
    Publication number: 20050148535
    Abstract: The present invention provides nucleobase oligomers and oligomer complexes that inhibit expression of an IAP polypeptide, and methods for using them to induce apoptosis in a cell. The nucleobase oligomers and oligomer complexes of the present invention may also be used to form pharmaceutical compositions. The invention also features methods for enhancing apoptosis in a cell by administering a nucleobase oligomer or oligomer complex of the invention in combination with a chemotherapeutic or chemosensitizing agent.
    Type: Application
    Filed: October 28, 2004
    Publication date: July 7, 2005
    Inventors: Eric LaCasse, Daniel McManus
  • Methods and reagents for the treatment of proliferative diseases
    Publication number: 20050119217
    Abstract: The invention features methods, compositions, and kits for treating a patient having a proliferative disease.
    Type: Application
    Filed: October 28, 2004
    Publication date: June 2, 2005
    Inventors: Eric LaCasse, Daniel McManus, Jon Durkin
  • Antisense IAP nucleobase oligomers and uses thereof
    Publication number: 20030190659
    Abstract: The present invention features nucleobase oligomers that hybridize to IAP polynucleotides, and methods for using them to enhance apoptosis and treat proliferative diseases.
    Type: Application
    Filed: March 27, 2003
    Publication date: October 9, 2003
    Inventors: Eric LaCasse, Daniel McManus, Jonathan P. Durkin