Abstract: A cartridge for pharmaceutical dispensing system, wherein the system is configured to dispense pouches containing medicaments, the pouches provided as a strip of a plurality of pouches, the strip provided in coiled form, includes: a main receptacle having a floor, a ceiling, a front wall, a rear wall, and a first side wall, wherein the front wall includes a slot for dispensing pouches; a cover that engages the main receptacle and provides a second side wall opposite the first side wall; and a guide system disposed in the main receptacle, the guide system defining an interior space configured to hold the strip of pouches in coiled form, and further defining a pathway between the guide system and the ceiling, rear wall, and floor.