Abstract: Methods described herein are useful for evaluating whether cells, that have previously undergone genetic modification, were successfully modified. Methods for determining whether a cell is a genetically modified cell involves a cell calling step and a dynamic normalization step that takes into consideration the variation of sequencing depth and number of working amplicons. Thus, the disclosed methods are able to more accurately and consistently identify successfully modified cells, even in situations where limited reads are available for analysis.

Abstract: An integrated magnetic shield and bearing holder useable with electric motors includes a shaft portion and a cover portion extending radially outward from the shaft portion. The shaft portion includes an inner wall defining a channel and a ledge extending radially inward from the inner wall. The cover portion includes a first layer, a second layer extending substantially parallel to the first layer, a magnetic shield extending between the first layer and the second layer, and an outer wall extending from the first layer and/or the second layer such that a space is defined between the outer wall and the shaft portion. The cover portion includes one or more retainers coupled to the magnetic shield to restrict movement of the magnetic shield relative to the first layer and/or the second layer.

Abstract: Cleavable primers are incorporated into single cell analysis workflows to reduce and/or eliminate misprimed nucleic acid amplicons. Specifically, cleavable primers can introduce restriction endonuclease cleavage sites into misprimed nucleic acid amplicons. For example, cleavable primers can introduce a restriction endonuclease cleavage site into an amplicon comprising DNA misprimed by an RNA primer. As another example, cleavable primers can introduce a restriction endonuclease cleavage site into an amplicon comprising cDNA misprimed by a DNA primer. Such amplicons can then be cleaved by a restriction endonuclease to remove them from identification and association in subsequent nucleic acid sequencing.

Abstract: An integrated magnetic shield and bearing holder useable with electric motors includes a shaft portion and a cover portion extending radially outward from the shaft portion. The shaft portion includes an inner wall defining a channel and a ledge extending radially inward from the inner wall. The cover portion includes a first layer, a second layer extending substantially parallel to the first layer, a magnetic shield extending between the first layer and the second layer, and an outer wall extending from the first layer and/or the second layer such that a space is defined between the outer wall and the shaft portion. The cover portion includes one or more retainers coupled to the magnetic shield to restrict movement of the magnetic shield relative to the first layer and/or the second layer.

Abstract: An apparatus includes a clip mounted to a base that pivots about a first pivot axis between a first position and a second position. An abutment surface of the clip is spaced from a path of a carrier structure when the clip is in the first position. The abutment surface engages the carrier structure to secure the carrier structure and a device to the apparatus when the clip is in the second clip position. A cam includes a first surface that pivots the clip to the first clip position when the cam is in the first cam position. The cam includes a second surface that extends into an opening of the base when the cam is in a first position to allow a stop plate pin to engage the cam to rotate the cam from the first position to a second position when a stop plate is installed.

Abstract: A deform lead-retract removal track is provided which is configured to convey non-defective integrated circuit packages and remove integrated circuit packages having a lead-retract defect. The distance between the outside walls of the track is less than the distance between leads of the non-defective integrated circuit packages and greater than the distance between the leads of the integrated circuit packages having a lead-retract defect. The defective integrated circuit packages having a lead-retract defect are unable to enter the track or will become stuck on the track.

Abstract: An apparatus includes a clip mounted to a base that pivots about a first pivot axis between a first position and a second position. An abutment surface of the clip is spaced from a path of a carrier structure when the clip is in the first position. The abutment surface engages the carrier structure to secure the carrier structure and a device to the apparatus when the clip is in the second clip position. A cam includes a first surface that pivots the clip to the first clip position when the cam is in the first cam position. The cam includes a second surface that extends into an opening of the base when the cam is in a first position to allow a stop plate pin to engage the cam to rotate the cam from the first position to a second position when a stop plate is installed.

Abstract: A tray loading system for tested electronic components including a tray loading bin adapted to prevent trays of a first configuration from being operably received in a first bin operating mode and to operably receive trays of the first configuration in a second bin operating mode. The system also includes an operating mode switching assembly adapted to automatically change from the second operating mode to the first operating mode in response to an operation associated with removal of loaded trays of the first configuration from the tray loading bin.

Abstract: A tray loading system for tested electronic components including a tray loading bin adapted to prevent trays of a first configuration from being operably received in a first bin operating mode and to operably receive trays of the first configuration in a second bin operating mode. The system also includes an operating mode switching assembly adapted to automatically change from the second operating mode to the first operating mode in response to an operation associated with removal of loaded trays of the first configuration from the tray loading bin.

Abstract: Fibered particles combine microscale spheroid particles and nanoscale fibers in an integrated body. Fibered particles may be combined with a matrix precursor to form syntactic foams incorporating both particles and fibers.

Abstract: Fibered particles combine microscale spheroid particles and nanoscale fibers in an integrated body. Fibered particles may be combined with a matrix precursor to form syntactic foams incorporating both particles and fibers.

Abstract: Method for producing metal oxide nanoparticles. The method includes generating an aerosol of solid metallic microparticles, generating plasma with a plasma hot zone at a temperature sufficiently high to vaporize the microparticles into metal vapor, and directing the aerosol into the hot zone of the plasma. The microparticles vaporize in the hot zone into metal vapor. The metal vapor is directed away from the hot zone and into the cooler plasma afterglow where it oxidizes, cools and condenses to form solid metal oxide nanoparticles.

Abstract: Method for producing metal oxide nanoparticles. The method includes generating an aerosol of solid metallic microparticles, generating plasma with a plasma hot zone at a temperature sufficiently high to vaporize the microparticles into metal vapor, and directing the aerosol into the hot zone of the plasma. The microparticles vaporize in the hot zone into metal vapor. The metal vapor is directed away from the hot zone and into the cooler plasma afterglow where it oxidizes, cools and condenses to form solid metal oxide nanoparticles.