Abstract: A blood circulation assist system includes a ventricular assist device (VAD) and a controller. The VAD is attachable to a heart of a patient to pump blood from a ventricle of the heart into a blood vessel of the patient. The VAD includes an impeller, a motor stator operable to rotate the impeller, and an accelerometer generating an accelerometer output indicative of accelerations of the VAD. The controller is configured to process the accelerometer output to generate patient monitoring data for the patient.

Abstract: Disclosed are sulfonamide compounds with GPR17 modulating properties, which are useful for treating or preventing a variety of CNS and other diseases, in particular for preventing and treating myelinating diseases or disorders.

Abstract: A blood circulation assist system includes a ventricular assist device (VAD) and a controller. The VAD is attachable to a heart of a patient to pump blood from a ventricle of the heart into a blood vessel of the patient. The VAD includes an impeller, a motor stator operable to rotate the impeller, and an accelerometer generating an accelerometer output indicative of accelerations of the VAD. The controller controls operation of the motor stator to control rotational speed of the impeller based on the accelerometer output.

Abstract: One embodiment of the present invention sets forth a technique for validating a set of input data used by a software application, the method comprising: determining a first validation class for a first portion of the set of input data; determining a first validation operation to be performed on the first portion of the set of input data based on the first validation class; causing the first validation operation to be performed on the first portion of the set of input data; determining that the first validation operation is unsuccessful; and generating a validation report indicating that the set of input data includes an error.

Abstract: A watercraft has a retractable lift-propulsion system including a mast connected to a buoyant body of the watercraft and movable between retracted and deployed positions. A distance between a distal end of the mast and a lower surface of the buoyant body is greater in the deployed position than in the retracted position. A lift-propulsion assembly includes a hydrofoil for providing lift to the watercraft at least in the deployed position of the mast and a propulsion unit for providing thrust to the watercraft in the retracted and deployed positions of the mast. The lift-propulsion assembly is connected to the distal end of the mast such that, in the deployed position of the mast, the lift-propulsion assembly is distanced from the buoyant body of the watercraft and, in the retracted position of the mast, the lift-propulsion assembly is proximate the buoyant body of the watercraft.

Abstract: A front suspension assembly for a vehicle having a connector adapted for connection to a front ground engaging member of the vehicle, a lower swing arm adapted for pivotal connection to a frame of the vehicle about a lower swing axis and being pivotally connected to the connector, an upper swing arm adapted for pivotal connection to the frame about an upper swing axis and being pivotally connected to the connector, the upper swing arm being above the lower swing arm, and a shock absorber assembly having a first end adapted for pivotal connection to the frame above the upper swing axis and a second end pivotally connected to the upper swing arm. The connector is pivotable relative to the lower and upper swing arms about a steering axis. A vehicle having the front suspension assembly is also disclosed.

Abstract: One embodiment of the present invention sets forth a technique for validating a set of input data used by a software application, the method comprising: determining a first validation class for a first portion of the set of input data; determining a first validation operation to be performed on the first portion of the set of input data based on the first validation class; causing the first validation operation to be performed on the first portion of the set of input data; determining that the first validation operation is unsuccessful; and generating a validation report indicating that the set of input data includes an error.

Abstract: One embodiment of the present invention sets forth a technique for validating a set of input data used by a software application, the method comprising: determining a first validation class for a first portion of the set of input data; determining a first validation operation to be performed on the first portion of the set of input data based on the first validation class; causing the first validation operation to be performed on the first portion of the set of input data; determining that the first validation operation is unsuccessful; and generating a validation report indicating that the set of input data includes an error.

Abstract: A wheel for a vehicle is provided. The wheel has a rim configured for mounting a tire thereto. The wheel also has a rotary drive member that is integrally connected to the rim. The drive member is configured to be operatively connected to a motor of the vehicle.

Abstract: A vehicle has a driver module and a propulsion module selectively connected to the driver module. The modules are separable from each other as independent units. The driver module has a driver module frame, at least one front wheel operatively connected to the driver module frame, at least one front suspension assembly operatively connecting the at least one front wheel to the driver module frame, and a seat connected to the frame. The propulsion module has a propulsion module frame, at least one rear wheel operatively connected to the propulsion module frame, at least one rear suspension assembly operatively connecting the at least one rear wheel to the propulsion module frame, a motor operatively connected to the at least one rear wheel, and an energy storage device operatively connected to the motor.

Abstract: One embodiment of the present invention sets forth a technique for validating a set of input data used by a software application, the method comprising: determining a first validation class for a first portion of the set of input data; determining a first validation operation to be performed on the first portion of the set of input data based on the first validation class; causing the first validation operation to be performed on the first portion of the set of input data; determining that the first validation operation is unsuccessful; and generating a validation report indicating that the set of input data includes an error.

Abstract: A vehicle has a driver module and a propulsion module selectively connected to the driver module. The modules are separable from each other as independent units. The driver module has a driver module frame, at least one front wheel operatively connected to the driver module frame, at least one front suspension assembly operatively connecting the at least one front wheel to the driver module frame, and a seat connected to the frame. The propulsion module has a propulsion module frame, at least one rear wheel operatively connected to the propulsion module frame, at least one rear suspension assembly operatively connecting the at least one rear wheel to the propulsion module frame, a motor operatively connected to the at least one rear wheel, and an energy storage device operatively connected to the motor.

Abstract: An electrosurgical instrument includes a housing including an elongated shaft. A stationary actuation member is axially disposed within the elongated shaft and includes a cam pin. An actuating mechanism is operably coupled to the elongated shaft and is moveable relative to the housing to selectively cause movement of the elongated shaft. An end effector includes a pair of opposing first and second jaw members operably coupled about a common pivot. One or both of the jaw members includes a camming slot configured to engage the cam pin. Each jaw member includes an electrically conductive tissue sealing surface adapted to connect to a source of electrosurgical energy. A knife blade is supported in the elongated shaft and moveable in a longitudinal direction to cut tissue disposed between the jaw members. A wire retention unit is supported within the housing and includes a plurality of wire clasps and a plurality of guide ribs configured to define at least one wire path.

Abstract: A wheel for a vehicle is provided. The wheel has a rim configured for mounting a tire thereto. The wheel also has a rotary drive member that is integrally connected to the rim. The drive member is configured to be operatively connected to a motor of the vehicle.

Abstract: A leaning vehicle has a frame; a shock tower pivotally connected to the frame; front left and right ground engaging members; front left and right suspension assemblies; portions of the front left suspension assembly, the front left ground engaging member and other components of the vehicle suspended by the front left suspension assembly have a first unsprung mass; portions of the front right suspension assembly, the front right ground engaging member and other components of the vehicle suspended by the front right suspension assembly have a second unsprung mass; a moment of inertia of the shock tower being at least twenty-five percent of a combined moment of inertia of the first and second unsprung masses; a steering assembly; a rear suspension assembly; at least one rear ground engaging; and a motor.

Abstract: A leaning vehicle has a frame; a shock tower pivotally connected to the frame; front left and right ground engaging members; front left and right suspension assemblies; portions of the front left suspension assembly, the front left ground engaging member and other components of the vehicle suspended by the front left suspension assembly have a first unsprung mass; portions of the front right suspension assembly, the front right ground engaging member and other components of the vehicle suspended by the front right suspension assembly have a second unsprung mass; a moment of inertia of the shock tower being at least twenty-five percent of a combined moment of inertia of the first and second unsprung masses; a steering assembly; a rear suspension assembly; at least one rear ground engaging; and a motor.

Abstract: A leaning vehicle has a frame, a motor, a shock tower pivotally connected to the frame about a frame leaning axis, front left and right ground engaging members connected to the shock tower via front left and right suspension assemblies, a steering assembly, a rear suspension assembly, and at least one rear ground engaging member. The front left and right suspension assemblies each include a lower suspension arm having a first end pivotally connected about a pivoting axis to the lower end of the shock tower and a second end pivotally connected about a tilting axis to its corresponding front ground engaging member, and a shock absorber having an upper end connected to the upper end of the shock tower and a lower end connected to the lower suspension arm. The frame is pivotable about the frame leaning axis relative to the pivoting axes.

Abstract: A leaning vehicle has a frame, a motor, a shock tower pivotally connected to the frame about a frame leaning axis, front left and right ground engaging members connected to the shock tower via front left and right suspension assemblies, a steering assembly, a rear suspension assembly, and at least one rear ground engaging member. The front left and right suspension assemblies each include a lower suspension arm having a first end pivotally connected about a pivoting axis to the lower end of the shock tower and a second end pivotally connected about a tilting axis to its corresponding front ground engaging member, and a shock absorber having an upper end connected to the upper end of the shock tower and a lower end connected to the lower suspension arm. The frame is pivotable about the frame leaning axis relative to the pivoting axes.

Abstract: A method for enhancing stability of a three wheel vehicle having a pair of front wheels and a single rear wheel, each of the wheels having a tire with a tire grip threshold. The method including deploying an electronic stability system (ESS) on the vehicle, providing the ESS with input from various vehicle sensors related to the longitudinal and lateral acceleration of the vehicle, causing the ESS to determine whether (i) a precursory condition indicative of a wheel lift exists and (ii) the tire grip threshold of any of the tires has been exceeded; and when a precursory condition indicative of a wheel lift exists and the tire grip threshold of none of the tires has been exceeded, causing the ESS to reduce the longitudinal acceleration of the vehicle by a first amount less than that which would cause the tire grip threshold of any of the tires to be exceeded.

Abstract: A ski and front track assembly has a track assembly including: an endless track, and at least two wheels disposed inside the track. At least one of the at least two wheels is disposed forwardly of at least one other of the at least two wheels. The ski and front track assembly also has a front ski element connected to the track assembly and extending forwardly therefrom. The front ski element is pivotable about a steering axis together with the track assembly. A snowmobile having the ski and front track assembly is also disclosed. A track assembly having a braking system and a snowmobile having the track assembly are also disclosed.