Abstract: An enclosure may be secured to an enclosure frame by a fastener that continuously extends through a first aperture of the enclosure and a second aperture of an isolator. The isolator may contact the first aperture, enclosure frame, and fastener. The second aperture can be shaped to dampen vibration frequencies between the enclosure frame and the enclosure.

Abstract: Disclosed herein are compounds of Formula I wherein R1, R2, X, and Y are defined herein. These compounds are type II topoisomerase inhibitors and can be used in methods for treating infections caused by gram-positive pathogens, gram-negative pathogens, and drug-resistant strains thereof.

Abstract: A modular fan assembly for use in a multi-device storage enclosure. In some embodiments, the fan assembly has a rigid open frame with opposing first and second ends. A first fan is connected to the first end and a second fan is connected to the second end. The first and second fans are configured to establish a fluidic airflow through the frame. An airflow diverter positioned in an intermediate portion of the frame between the first and second ends divert at least a portion of the fluidic airflow through a first aperture of the frame to cool an active element outside the frame.

Abstract: An enclosure may be secured to an enclosure frame by a fastener that continuously extends through a first aperture of the enclosure and a second aperture of an isolator. The isolator may contact the first aperture, enclosure frame, and fastener. The second aperture can be shaped to dampen vibration frequencies between the enclosure frame and the enclosure.

Abstract: This invention provides novel 4-oxoquinolizine compounds and their uses for a series of broad-spectrum antibiotics having no cross-resistance to existing or emerging classes of antibiotics. In addition the novel 4-oxoquinolizine compounds are useful against CDC Category A and B pathogens The invention also provides pharmaceutical compositions comprising certain 4-oxoquinolizines in combination with subinhibitory concentrations of polymyxin B against clinical isolates which are resistant to quinolones, carbapenems and other antimicrobial agents.

Abstract: This invention provides novel 4-oxoquinolizine compounds and their uses for a series of broad-spectrum antibiotics having no cross-resistance to existing or emerging classes of antibiotics. In addition the novel 4-oxoquinolizine compounds are useful against CDC Category A and B pathogens. The invention also provides pharmaceutical compositions comprising certain 4-oxoquinolizines in combination with subinhibitory concentrations of polymyxin B against clinical isolates which are resistant to quinolones, carbapenems and other antimicrobial agents.

Abstract: Disclosed herein are compounds of Formula I wherein R1, R2, X, and Y are defined herein. These compounds are type II topoisomerase inhibitors and can be used in methods for treating infections caused by gram-positive pathogens, gram-negative pathogens, and drug-resistant strains thereof.

Abstract: A data storage enclosure may house at least two data storage devices and consist of a first electrical connector and a latch feature. The first electrical connector may be aligned with a second electrical connector of a data storage rack. The latch feature can be configured to contact a frame of the data storage rack to prevent the first and second electrical connectors from contacting until a lever of the latch feature is activated.

Abstract: A modular fan assembly for use in a multi-device storage enclosure. In some embodiments, the fan assembly has a rigid open frame with opposing first and second ends. A first fan is connected to the first end and a second fan is connected to the second end. The first and second fans are configured to establish a fluidic airflow through the frame. An airflow diverter positioned in an intermediate portion of the frame between the first and second ends divert at least a portion of the fluidic airflow through a first aperture of the frame to cool an active element outside the frame.

Abstract: This invention provides novel 4-oxoquinolizine compounds and their uses for a series of broad-spectrum antibiotics having no cross-resistance to existing or emerging classes of antibiotics. In addition the novel 4-oxoquinolizine compounds are useful against CDC Category A and B pathogens The invention also provides pharmaceutical compositions comprising certain 4-oxoquinolizines in combination with subinhibitory concentrations of polymyxin B against clinical isolates which are resistant to quinolones, carbapenems and other antimicrobial agents.

Abstract: Disclosed herein are compounds of Formula I wherein R1, R2, X, and Y are defined herein. These compounds are type II topoisomerase inhibitors and can be used in methods for treating infections caused by gram-positive pathogens, gram-negative pathogens, and drug-resistant strains thereof.

Abstract: A modular fan assembly for use in a multi-device storage enclosure. In some embodiments, the fan assembly has a rigid open frame with opposing first and second ends. A first fan is connected to the first end and a second fan is connected to the second end. The first and second fans are configured to establish a fluidic airflow through the frame. An airflow diverter positioned in an intermediate portion of the frame between the first and second ends divert at least a portion of the fluidic airflow through a first aperture of the frame to cool an active element outside the frame.

Abstract: This invention provides novel 4-oxoquinolizine compounds and their uses for a series of broad-spectrum antibiotics having no cross-resistance to existing or emerging classes of antibiotics. In addition the novel 4-oxoquinolizine compounds are useful against CDC Category A and B pathogens The invention also provides pharmaceutical compositions comprising certain 4-oxoquinolizines in combination with subinhibitory concentrations of polymyxin B against clinical isolates which are resistant to quinolones, carbapenems and other antimicrobial agents.

Abstract: An apparatus as associated method contemplating a housing and a midplane supported by the housing having a midplane connector. A printed circuit board (PCB) having a PCB connector is selectively connectable to the midplane connector. A plurality of data storage devices are arranged on the printed circuit board in a staggered pattern, each electrically connected to the PCB connector via a respective electrical trace in the PCB.

Abstract: This invention provides novel 4-oxoquinolizine compounds and their uses for a series of broad-spectrum antibiotics having no cross-resistance to existing or emerging classes of antibiotics. In addition the novel 4-oxoquinolizine compounds are useful against CDC Category A and B pathogens The invention also provides pharmaceutical compositions comprising certain 4-oxoquinolizines in combination with subinhibitory concentrations of polymyxin B against clinical isolates which are resistant to quinolones, carbapenems and other antimicrobial agents.

Abstract: A data storage enclosure may house at least two data storage devices and consist of a first electrical connector and a latch feature. The first electrical connector may be aligned with a second electrical connector of a data storage rack. The latch feature can be configured to contact a frame of the data storage rack to prevent the first and second electrical connectors from contacting until a lever of the latch feature is activated.

Abstract: An enclosure may be secured to an enclosure frame by a fastener that continuously extends through a first aperture of the enclosure and a second aperture of an isolator. The isolator may contact the first aperture, enclosure frame, and fastener. The second aperture can be shaped to dampen vibration frequencies between the enclosure frame and the enclosure.

Abstract: An apparatus as associated method contemplating a housing and a midplane supported by the housing having a midplane connector. A printed circuit board (PCB) having a PCB connector is selectively connectable to the midplane connector. A plurality of data storage devices are arranged on the printed circuit board in a staggered pattern, each electrically connected to the PCB connector via a respective electrical trace in the PCB.

Abstract: Disclosed herein are compounds of Formula I wherein R1, R2, X, and Y are defined herein. These compounds are type II topoisomerase inhibitors and can be used in methods for treating infections caused by gram-positive pathogens, gram-negative pathogens, and drug-resistant strains thereof.

Abstract: Described are a series of 2-pyridone compounds as a potent and selective new class of type II topoisomerase inhibitors with broad-spectrum antimicrobial activity having the general formula (I); where R1, R2, X, and Y are defined herein Such compounds can be used in methods for treating an infection caused by a gram-positive pathogen, a gram-negative pathogen, or a drug-resistant strains thereof.