Abstract: The present invention relates to the (S)-enantiomer of mepazine, its applicability in therapy, a pharmacological composition comprising (S)-mepazine, and processes for the preparation of (S)-mepazine and one of its intermediates.

Abstract: A television screen protector assembly for mounting to a conventional television and protecting the screen panel of the television on which it is mounting. The television screen protector assembly includes a pair of holding brackets, each having an attaching surface for attaching to the television and a receiving slot for slidingly receiving a removable protecting screen (or “removable screen”) and a pair of impact brackets, each having an attaching surface, impact pads for preventing the protecting screen from impacting the television and a swinging closure for enabling selective control of the insertion and removal of the removable screen in the receiving slots. The removable screen defines a rigid, transparent rectangular member that while held in place by the brackets, shields the screen panel of a conventional television.

Abstract: The invention relates to a compound for use in treating a cancer, wherein the cancer depends on the proteolytic activity of the MALT1 protease, and wherein the compound has the general formula (I) wherein X is N or C; Y is S, O, SO2, SO, NH, CO, CH2, CH?CH, or CH2—CH2; ( )z is a C1-C5 linear or branched alkyl chain; A is NR3R4, or OR5, or HET; R1 and R2 in each occurrence are independently selected from —H, —CH3, —OH, —OCH3, —SCH3, —F, —Cl, —CF3, —NH2, and —COOH; R3, R4, and R5 are H, or C1-C5 linear or branched alkyl groups, and HET is a heterocyclic ring of 5, 6, or 7 members, wherein the ring atoms can be C, O, N, or S, the ring can be saturated or aromatic, and the ring can be substituted with H or C1-C5 linear or branched alkyl groups; or a pharmaceutically acceptable salt, prodrug, enantiomer, diastereomer, racemic mixture, crystalline form, amorphous form, unsolvated form or solvate of said compound.

Abstract: The present invention relates to the (S)-enantiomer of mepazine, its applicability in therapy, a pharmacological composition comprising (S)-mepazine, and processes for the preparation of (S)-mepazine and one of its intermediates.

Abstract: The invention relates to a compound for use in treating a cancer, wherein the cancer depends on the proteolytic activity of the MALT1 protease, and wherein the compound has the general formula (I) wherein X is N or C; Y is S, O, SO2, SO, NH, CO, CH2, CH?CH, CH2?CH2; ( )z is a C1-C5 linear or branched alkyl chain; A is NR3R4, or OR5, or HET; R1 and R2 in each occurrence are independently selected from —H, —CH3, —OH, —OCH3, —SCH3, —F, —Cl, —CF3, —NH2, and —COOH; R3, R4, and R5 are H, or C1-C5 linear or branched alkyl groups, and HET is a heterocyclic ring of 5, 6, or 7 members, wherein the ring atoms can be C, O, N, or S, the ring can be saturated or aromatic, and the ring can be substituted with H or C1-C5 linear or branched alkyl groups; or a pharmaceutically acceptable salt, prodrug, enantiomer, diastereomer, racemic mixture, crystalline form, amorphous form, unsolvated form or solvate of said compound. The compound of the invention may further be used in the treatment of MALT1-dependent immune diseases.

Abstract: A multi-stage odor scrubber comprising a first stage odor scrubber comprising a first contact chamber, a first sump for collecting liquids and a first recirculation pump. The multi-stage scrubber further comprises a second stage odor scrubber, the second stage odor scrubber comprising a venturi chamber with one or more venturi adjacent the first contact chamber, and a third contact chamber. The venturi chamber is positioned between the first and third contact chambers. A unitary housing contains the first and second stage odor scrubbers. The second stage odor scrubber further comprises a second sump for collecting liquids from the venturi chamber and the third contact chamber, and a second recirculation pump for re-circulating liquid. A method for removing contaminants from a gas stream comprises propelling a contaminated gas stream through the multi-stage odor scrubber.