Abstract: The disclosure relates to block copolymer nanoparticles for in vivo therapeutic delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticles, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, for encapsulation and for delivery of large nucleic acids.

Abstract: Magnetic field sensors and methods for 3D-printing of the same are disclosed. The magnetic field sensor includes a monolithic body with a plurality of coils 3D-printed therein by successive printing of layers along a printing direction; the coils include longitudinally oriented coil(s) whose magnetic axe(s) are parallel to the printing direction and transversely oriented coil(s) whose magnetic axe(s) are perpendicular to the printing direction. The transversely oriented coil(s) is each 3D-printed with a magnetic channel that curves between a pair of opposite flux collection facets being perpendicular to its magnetic axis, such that it includes a magnetic core section extending along the printing direction. Each of the longitudinally and transversely oriented coils is 3D-printed with respective arrangement of conductive windings including a plurality of turns 3D-printed in planes of the 3D-printed layers.

Abstract: Electric components including coils and methods to fabricate the same by 3D-printing are disclosed. The method includes: 3D printing a magnetic material to form a magnetic channel comprising a magnetic core of the coil device; 3D printing a conductive material to form a conductive channel, including conductive windings of the coil device with turns surrounding the magnetic core; and 3D printing a non-magnetic electrically insulating material to form electrical insulation between the turns of the conductive windings of the coil device. In some embodiments functional structures of the electric component, including the turns of the conductive windings of the coil and the electrical insulation between the turns, are each printed with minimal in-layer feature size of at least two voxels of the 3D-printing. Some embodiments facilitate 3D-printing of flattened coil devices having low aspect ratio between their lengths along their magnetic axes and their widths perpendicular thereto.

Abstract: An electric component having electric coils, the component formed by 3D printing of at least three different 3D-printed materials with spatial distributions yielding open magnetic circuit configuration of one of the electric coils. The electric component having a bulk formed by non-magnetic and dielectric 3D printed material; and an electric coil of the open magnetic circuit configuration, 3D-printed in the bulk. A magnetic channel of magnetic material 3D-printed in the bulk forming magnetic core of the electric coil; and an electric channel forming an inductor of the electric coil having conductive material 3D-printed in the bulk with a coil/helical geometry having electrically connected conductive windings arranged to circumference the magnetic channel, which is configured and operable with the open magnetic circuit configuration and has magnetic material occupying a central region of the coil/helical geometry of the inductor while not enclosing the windings with a closed loop of the magnetic material.

Abstract: An optical measurement system and apparatus for carrying out cataract diagnostics in an eye of a patient includes a Corneal Topography Subsystem, a wavefront aberrometer subsystem, and an eye structure imaging subsystem, wherein the subsystems have a shared optical axis, and each subsystem is operatively coupled to the others via a controller. The eye structure imaging subsystem is preferably a fourierdomain optical coherence tomographer, and more preferably, a swept source OCT.

Abstract: An optical measurement system and apparatus for carrying out cataract diagnostics in an eye of a patient includes a Corneal Topography Subsystem, a wavefront aberrometer subsystem, and an eye structure imaging subsystem, wherein the subsystems have a shared optical axis, and each subsystem is operatively coupled to the others via a controller. The eye structure imaging subsystem is preferably a fourierdomain optical coherence tomographer, and more preferably, a swept source OCT.

Abstract: An optical measurement system and apparatus for carrying out cataract diagnostics in an eye of a patient includes a Corneal Topography Subsystem, a wavefront aberrometer subsystem, and an eye structure imaging subsystem, wherein the subsystems have a shared optical axis, and each subsystem is operatively coupled to the others via a controller. The eye structure imaging subsystem is preferably a fourierdomain optical coherence tomographer, and more preferably, a swept source OCT.

Abstract: An optical measurement system and apparatus for carrying out cataract diagnostics in an eye of a patient includes a Corneal Topography Subsystem, a wavefront aberrometer subsystem, and an eye structure imaging subsystem, wherein the subsystems have a shared optical axis, and each subsystem is operatively coupled to the others via a controller. The eye structure imaging subsystem is preferably a fourierdomain optical coherence tomographer, and more preferably, a swept source OCT.

Abstract: Devices, systems, and methods for administering therapy to restore limb motion to patients in need are disclosed. The system may include a motion capture device to capture an exercise performed by a therapist. The exercise may be retrieved by the patient and used to generate a visual display used to guide the patient through the exercise in real time.

Abstract: Disclosed herein is a digital processing system for transferring data for remote access across a multicomputer data network. In one embodiment, the digital processing system is configured to receive user input, analyze the data input, assign a reference tag to the data input based on contextual information associated with the data input, and store the reference tag within a memory device that may be accessed by one or more users of the multicomputer data network.

Abstract: An optical measurement system and apparatus for carrying out cataract diagnostics in an eye of a patient includes a Corneal Topography Subsystem, a wavefront aberrometer subsystem, and an eye structure imaging subsystem, wherein the subsystems have a shared optical axis, and each subsystem is operatively coupled to the others via a controller. The eye structure imaging subsystem is preferably a fourierdomain optical coherence tomographer, and more preferably, a swept source OCT.

Abstract: Disclosed herein is a digital processing system for transferring data for remote access across a multicomputer data network. In one embodiment, the digital processing system is configured to receive user input, analyze the data input, assign a reference tag to the data input based on contextual information associated with the data input, and store the reference tag within a memory device that may be accessed by one or more users of the multicomputer data network.

Abstract: Devices, systems, and methods for administering therapy to restore limb motion to patients in need are disclosed. The system may include a motion capture device to capture an exercise performed by a therapist. The exercise may be retrieved by the patient and used to generate a visual display used to guide the patient through the exercise in real time.

Abstract: Embodiments of this invention generally relate to systems and methods for wavefront interactive refraction display and more particularly to systems and methods for capturing and displaying eye wavefront interactive refraction data based on the desired refractive state of the patient's eye.

Abstract: A method of assembling an enclosure of a gas turbine is provided. The method includes disposing gas turbine equipment in an interior of a frame at a first site, connecting wall panels to the frame to form a pre-assembled module at the first site, shipping the pre-assembled module from the first site to a second site and disposing the pre-assembled module proximate to the gas turbine such that the gas turbine equipment is exposed for connection to the gas turbine and a portion of the wall panels form a portion of an outer enclosure of the gas turbine and the gas turbine equipment.

Abstract: A gas turbine enclosure apparatus is provided and includes a frame defining an interior, gas turbine equipment disposed in the interior, the gas turbine equipment being pre-assembled at a first site and connectable with a gas turbine disposed at a second site and wall panels connectable with the frame. The apparatus being disposable proximate to the gas turbine such that the gas turbine equipment is exposed to the gas turbine and a portion of the wall panels form a portion of an outer enclosure of the gas turbine and the gas turbine equipment.

Abstract: Embodiments of this invention generally relate to systems and methods for wavefront interactive refraction display and more particularly to systems and methods for capturing and displaying eye wavefront interactive refraction data based on the desired refractive state of the patient's eye.

Abstract: A method of performing refractive laser eye surgery on a human eye is provided wherein the ablation pattern is centered along the visual axis, rather than along the line of sight. First, a wavefront, either ocular, corneal or a combination thereof, is generated by a wavefront sensor centered along the line of sight. This measured wavefront is centered on and encompasses a patient's pupil. Then, an analysis pupil is determined which encompasses the measured pupil. The analysis pupil is centered along the visual axis at the point of intersection with the cornea. Consequently, the measured wavefront is reconstructed over the analysis pupil only using data taken over the area covered by the measured pupil. This reconstruction is done through a least squares fit of a series of slopes from the measured wavefront and/or through the transformation of aberration coefficients.