Patents by Inventor Daniel Neems
Daniel Neems has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11848107Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: GrantFiled: December 21, 2021Date of Patent: December 19, 2023Assignee: Tempus Labs, Inc.Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Patent number: 11532397Abstract: A system, method, and mobile device application are configured to capture, with a mobile device, a document such as a next generation sequencing (NGS) report that includes NGS medical information about a genetically sequenced patient. The method includes receiving, from a mobile device, an image of a medical document comprising NGS medical information of the patient, extracting a first region from the image, extracting NGS medical information of the patient from the first region into a structured dataset, the extracted NGS medical information including at least one RNA expression, correlating a portion of the extracted NGS medical information that includes the at least one RNA expression with summarized medical information from a cohort of patients similar to the patient, and generating, for display on the mobile device, a clinical decision support report comprising the summarized medical information.Type: GrantFiled: January 25, 2021Date of Patent: December 20, 2022Assignee: Tempus Labs, Inc.Inventors: Michael Ryan Lucas, Jonathan Ozeran, Jason L. Taylor, Louis E. Fernandes, Daniel Neems, Hunter Lane, Eric Lefkofsky
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Publication number: 20220148736Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: ApplicationFiled: December 21, 2021Publication date: May 12, 2022Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Patent number: 11244763Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: GrantFiled: July 12, 2021Date of Patent: February 8, 2022Assignee: Tempus Labs, Inc.Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Publication number: 20210343419Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: ApplicationFiled: July 12, 2021Publication date: November 4, 2021Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Publication number: 20210319906Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: ApplicationFiled: April 9, 2021Publication date: October 14, 2021Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Patent number: 11145416Abstract: Systems and methods are provided for predicting metastasis of a cancer in a subject. A plurality of data elements for the subject's cancer is obtained, including sequence features comprising relative abundance values for gene expression in a cancer biopsy of the subject, optional personal characteristics about the subject, and optional clinical features related to the stage, histopathological grade, diagnosis, symptom, comorbidity, and/or treatment of the cancer in the subject, and/or a temporal element associated therewith. One or more models are applied to the plurality of data elements, determining one or more indications of whether the cancer will metastasize. A clinical report comprising the one or more indications is generated.Type: GrantFiled: April 9, 2021Date of Patent: October 12, 2021Assignee: Tempus Labs, Inc.Inventors: Ashraf Hafez, Martin Christian Stumpe, Nike Beaubier, Daniel Neems, Caroline Epstein, Adrian William George Lange
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Publication number: 20210151192Abstract: A system, method, and mobile device application are configured to capture, with a mobile device, a document such as a next generation sequencing (NGS) report that includes NGS medical information about a genetically sequenced patient. The method includes receiving, from a mobile device, an image of a medical document comprising NGS medical information of the patient, extracting a first region from the image, extracting NGS medical information of the patient from the first region into a structured dataset, the extracted NGS medical information including at least one RNA expression, correlating a portion of the extracted NGS medical information that includes the at least one RNA expression with summarized medical information from a cohort of patients similar to the patient, and generating, for display on the mobile device, a clinical decision support report comprising the summarized medical information.Type: ApplicationFiled: January 25, 2021Publication date: May 20, 2021Inventors: Michael Ryan Lucas, Jonathan Ozeran, Jason L. Taylor, Louis E. Fernandes, Daniel Neems, Hunter Lane, Eric Lefkofsky
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Patent number: 10902952Abstract: A system, method, and mobile device application are configured to capture, with a mobile device, a document such as a next generation sequencing (NGS) report that includes NGS medical information about a genetically sequenced patient. At least some of the information is extracted from the document using an entity linking engine, and the extracted information is provided into a structured data repository where it is accessible to provide information regarding the patient specifically as well as collectively as part of a cohort of patients with similar genetic variants, medical histories, or other commonalities. In one aspect, the document is matched to a template model, and the document is processed using one or more masks segregating the template model, and therefore the document, into a series of distinct subregions.Type: GrantFiled: August 2, 2019Date of Patent: January 26, 2021Assignee: Tempus Labs, Inc.Inventors: Michael Ryan Lucas, Jonathan Ozeran, Jason L Taylor, Louis E. Fernandes, Daniel Neems, Hunter Lane, Eric Lefkofsky
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Publication number: 20200126663Abstract: A system, method, and mobile device application are configured to capture, with a mobile device, a document such as a next generation sequencing (NGS) report that includes NGS medical information about a genetically sequenced patient. At least some of the information is extracted from the document using an entity linking engine, and the extracted information is provided into a structured data repository where it is accessible to provide information regarding the patient specifically as well as collectively as part of a cohort of patients with similar genetic variants, medical histories, or other commonalities. In one aspect, the document is matched to a template model, and the document is processed using one or more masks segregating the template model, and therefore the document, into a series of distinct subregions.Type: ApplicationFiled: August 2, 2019Publication date: April 23, 2020Inventors: Michael Ryan Lucas, Jonathan Ozeran, Jason L. Taylor, Louis E. Fernandes, Daniel Neems, Hunter Lane, Eric Lefkofsky
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Patent number: 10395772Abstract: A system, method, and mobile device application are configured to capture, with a mobile device, a document such as a next generation sequencing (NGS) report that includes NGS medical information about a genetically sequenced patient. At least some of the information is extracted from the document using an entity linking engine, and the extracted information is provided into a structured data repository where it is accessible to provide information regarding the patient specifically as well as collectively as part of a cohort of patients with similar genetic variants, medical histories, or other commonalities. In one aspect, the document is matched to a template model, and the document is processed using one or more masks segregating the template model, and therefore the document, into a series of distinct subregions.Type: GrantFiled: February 28, 2019Date of Patent: August 27, 2019Assignee: Tempus LabsInventors: Michael Ryan Lucas, Jonathan Ozeran, Jason L. Taylor, Louis E. Fernandes, Daniel Neems, Hunter Lane, Eric Lefkofsky