Abstract: An equipment bag includes a shell comprising interior surfaces defining an interior volume defined by a first height, a first width, and a first length, where the shell comprises lengthwise portions forming a circumferential enclosure along the first length shell and two end portions positioned at opposite ends of the lengthwise portions enclosing the interior volume about the first height and the first width of the shell, a removable heating element, where the removable heating element includes heating panels defined by a second length and a second width, the second length corresponding to dimensions of a perimeter of the interior volume defined by the first width and the first height and the second width corresponding to the first length of the interior volume, and fasteners positioned at locations on interior surfaces of the shell such that the removable heating element is selectively attached to the interior surfaces of the shell.

Abstract: Provided herein are methods of administering ISIS 443139 for ameliorating Huntington's disease, reducing HTT RNA, reducing mHTT RNA, reducing HTT protein, or reducing mHTT protein in a human subject in need thereof. In certain instances, methods are useful for ameliorating at least one symptom of Huntington's disease. Such symptoms of Huntington's disease include, but are not limited to, brain atrophy, muscle atrophy, nerve degeneration, uncontrolled movement, difficulty swallowing, difficulty speaking, anxiety and depression.

Abstract: The field of this invention is technology that supports and enhances natural face-to-face communication. Throughout the recent Pandemic, people have been adversely affected by the loss of real face-to-face human contact. The invention provides one or more safe ‘meeting spaces’ through which persons can talk to each other normally, without the risk of airborne pathogens passing between them. The meeting space of the invention offers no physical barrier such as glass, which would reduce the quality of communication and diminish the user experience. Persons may see and hear each other through the meeting space but pathogens cannot substantially pass through it. Various ways are provided that substantially destroy/inactivate/remove pathogens from the meeting space(s). Some embodiments are sustainable, carbon neutral and solar powered. Others are highly energy efficient. Further refinements create a pleasant environment for conversation and enhance the user experience.

Abstract: Example embodiments relate to a network-based vulnerability detection system configured to access a database of customer transaction data corresponding to a set of card readers that includes transaction codes, receive an identification of a set of compromised card readers among the set of card readers, identify common transaction codes within the transaction data of the set of compromised card readers, and correlate the common transaction codes to one or more instances of fraud associated with the compromised set of card readers. In some example embodiments, the vulnerability detection system may be applied to monitor one or more card readers, receive transaction data corresponding to transaction conducted through the card readers, identify the common transaction codes correlated to the instances of fraud, and cause display of a notification that includes an indication of the instance of fraud at a client device.

Abstract: A submersible sieve apparatus provided with an exoskeletal frame enveloping a filter element and a detached post-filter backing; positioned to strain a lotic stream of entrained sediment prior to or upon being deposited. The frame can positioned and manipulated for greater efficiency. The filter and backing will take the shape of the frame and the backing may or may not be attached.

Abstract: Dosage regimens for SOD1-targeting antisense oligonucleotides, and salts thereof, are provided. These dosage regimens find use in the treatment of subjects having or at risk of developing amyotrophic lateral sclerosis.

Abstract: An equipment bag includes a shell comprising interior surfaces defining an interior volume defined by a first height, a first width, and a first length, where the shell comprises lengthwise portions forming a circumferential enclosure along the first length shell and two end portions positioned at opposite ends of the lengthwise portions enclosing the interior volume about the first height and the first width of the shell, a removable heating element, where the removable heating element includes heating panels defined by a second length and a second width, the second length corresponding to dimensions of a perimeter of the interior volume defined by the first width and the first height and the second width corresponding to the first length of the interior volume, and fasteners positioned at locations on interior surfaces of the shell such that the removable heating element is selectively attached to the interior surfaces of the shell.

Abstract: Example embodiments relate to a network-based vulnerability detection system configured to access a database of customer transaction data corresponding to a set of card readers that includes transaction codes, receive an identification of a set of compromised card readers among the set of card readers, identify common transaction codes within the transaction data of the set of compromised card readers, and correlate the common transaction codes to one or more instances of fraud associated with the compromised set of card readers. In some example embodiments, the vulnerability detection system may be applied to monitor one or more card readers, receive transaction data corresponding to transaction conducted through the card readers, identify the common transaction codes correlated to the instances of fraud, and cause display of a notification that includes an indication of the instance of fraud at a client device.

Abstract: A communications system and method structures and coordinates face-to-face communication and face-to-face networking, providing new functionality, a better user experience, new commercial uses and new business methods for its monetization. Pathway versions of the system and method are a more dynamic variant, structuring user conversations as they move from one location to another, while tracking the mutation of discussion topics from one subject to another. A configurable version of the system and method enables it to be built in any business place, customized and configured to that specific location. New features of the system and method now combine face-to-face communication with online communication in ways that were not previously possible.

Abstract: Example embodiments relate to a network-based vulnerability detection system configured to access a database of customer transaction data corresponding to a set of card readers that includes transaction codes, receive an identification of a set of compromised card readers among the set of card readers, identify common transaction codes within the transaction data of the set of compromised card readers, and correlate the common transaction codes to one or more instances of fraud associated with the compromised set of card readers. In some example embodiments, the vulnerability detection system may be applied to monitor one or more card readers, receive transaction data corresponding to transaction conducted through the card readers, identify the common transaction codes correlated to the instances of fraud, and cause display of a notification that includes an indication of the instance of fraud at a client device.

Abstract: A backpack with an improved load adjustment system includes a body, a frame, a pair of shoulder straps, a load lifting strap extending from each of the first shoulder strap and the second shoulder strap and suspended by the frame, a yoke attached to the first shoulder strap and the second shoulder strap, a back panel attached to a hip belt having a first hip pad and a second hip pad, and a torso length adjustment strap extending from a first lower side portion of the frame to a second lower side portion of the frame opposite the first lower side portion of the frame and passing through a strap receiving member fixed to the yoke. The improved load adjustment system allows for quick adjustment while wearing the backpack and increased freedom of movement.

Abstract: Multi-climate sleeping bags and methods of making the same are described. One sleeping bag may comprise a bottom panel comprising a head end and a foot end, wherein the bottom panel is formed from an inner shell, an outer shell, and an insulating material disposed between the inner shell and the outer shell, a first top panel comprising an inner shell, an outer shell, and an insulating material disposed between the inner shell and the outer shell, a first fastening mechanism configured to detachably couple an edge of the first top panel to an edge of the bottom panel, a second top panel comprising an inner shell, an outer shell, and an insulating material disposed between the inner shell and the outer shell, and a second fastening mechanism configured to detachably couple an edge of the second top panel to the edge of the bottom panel.

Abstract: A submersible sieve apparatus provided with an exoskeletal frame enveloping a filter element and a detached post-filter backing; positioned to strain a lotic stream of entrained sediment prior to or upon being deposited. The frame can positioned and manipulated for greater efficiency. The filter and backing will take the shape of the frame and the backing may or may not be attached.

Abstract: Example embodiments relate to a network-based vulnerability detection system configured to access a database of customer transaction data corresponding to a set of card readers that includes transaction codes, receive an identification of a set of compromised card readers among the set of card readers, identify common transaction codes within the transaction data of the set of compromised card readers, and correlate the common transaction codes to one or more instances of fraud associated with the compromised set of card readers. In some example embodiments, the vulnerability detection system may be applied to monitor one or more card readers, receive transaction data corresponding to transaction conducted through the card readers, identify the common transaction codes correlated to the instances of fraud, and cause display of a notification that includes an indication of the instance of fraud at a client device.

Abstract: Example embodiments relate to a network-based vulnerability detection system configured to access a database of customer transaction data corresponding to a set of card readers that includes transaction codes, receive an identification of a set of compromised card readers among the set of card readers, identify common transaction codes within the transaction data of the set of compromised card readers, and correlate the common transaction codes to one or more instances of fraud associated with the compromised set of card readers. In some example embodiments, the vulnerability detection system may be applied to monitor one or more card readers, receive transaction data corresponding to transaction conducted through the card readers, identify the common transaction codes correlated to the instances of fraud, and cause display of a notification that includes an indication of the instance of fraud at a client device.

Abstract: A backpack with an improved load adjustment system includes a body, a frame, a pair of shoulder straps, a load lifting strap extending from each of the first shoulder strap and the second shoulder strap and suspended by the frame, a yoke attached to the first shoulder strap and the second shoulder strap, a back panel attached to a hip belt having a first hip pad and a second hip pad, and a torso length adjustment strap extending from a first lower side portion of the frame to a second lower side portion of the frame opposite the first lower side portion of the frame and passing through a strap receiving member fixed to the yoke. The improved load adjustment system allows for quick adjustment while wearing the backpack and increased freedom of movement.

Abstract: Multi-climate sleeping bags and methods of making the same are described. One sleeping bag may comprise a bottom panel comprising a head end and a foot end, wherein the bottom panel is formed from an inner shell, an outer shell, and an insulating material disposed between the inner shell and the outer shell, a first top panel comprising an inner shell, an outer shell, and an insulating material disposed between the inner shell and the outer shell, a first fastening mechanism configured to detachably couple an edge of the first top panel to an edge of the bottom panel, a second top panel comprising an inner shell, an outer shell, and an insulating material disposed between the inner shell and the outer shell, and a second fastening mechanism configured to detachably couple an edge of the second top panel to the edge of the bottom panel.

Abstract: Example embodiments relate to a network-based vulnerability detection system configured to access a database of customer transaction data corresponding to a set of card readers that includes transaction codes, receive an identification of a set of compromised card readers among the set of card readers, identify common transaction codes within the transaction data of the set of compromised card readers, and correlate the common transaction codes to one or more instances of fraud associated with the compromised set of card readers. In some example embodiments, the vulnerability detection system may be applied to monitor one or more card readers, receive transaction data corresponding to transaction conducted through the card readers, identify the common transaction codes correlated to the instances of fraud, and cause display of a notification that includes an indication of the instance of fraud at a client device.

Abstract: Approaches for determining a potential merchant breach are described. A system can acquire card transaction data from one or more sources such as merchants or financial institutions, in some instances at a predetermined time interval. Cards associated with the card transaction data can be analyzed to determine the health of a particular card, including the likelihood that the particular card has been compromised. A set of cards are accumulated, and their associated health data is stored. Based on the information obtained from a source, and the health associated with a set of cards, a potential date where a merchant was breached can be determined and fraudulent purchases can be prevented.

Abstract: Approaches for determining a potential merchant breach are described. A system can acquire card transaction data from one or more sources such as merchants or financial institutions, in some instances at a predetermined time interval. Cards associated with the card transaction data can be analyzed to determine the health of a particular card, including the likelihood that the particular card has been compromised. A set of cards are accumulated, and their associated health data is stored. Based on the information obtained from a source, and the health associated with a set of cards, a potential date where a merchant was breached can be determined and fraudulent purchases can be prevented.