Abstract: Embodiments of the present invention provide an improved vascular occlusion device for occlusion of a passageway, cavity, or the like. According to one embodiment, a medical device for occluding a left atrial appendage is provided. The medical device includes a first portion having at least one plane of occlusion that is configured to be positioned outside of the left atrial appendage, and a second portion having at least one plane of occlusion that is configured to be at least partially positioned within a cavity defined by the left atrial appendage.

Abstract: A method is provided for manufacturing a container. During this method, a baffle is provided. The baffle is configured from or otherwise includes baffle thermoplastic material. A sidewall is formed using an additive manufacturing device. The sidewall is bonded to the baffle during the forming of the sidewall. The sidewall circumscribes the baffle. The sidewall is configured from or otherwise includes sidewall thermoplastic material. The container includes an internal chamber, the baffle and the sidewall. The sidewall forms an outer peripheral boundary of the internal chamber. The baffle is arranged within the internal chamber.

Abstract: A thermoplastic part for an aircraft includes a thermoplastic skin, a conductive metal layer, a thermoplastic resin film, and a paint coating. The thermoplastic skin includes an inner skin side and an outer skin side. The conductive metal layer includes an inner layer side and an outer layer side. The inner layer side is disposed at the outer skin side of the thermoplastic skin. The thermoplastic resin film including an inner film side and an outer film side. The inner film side is disposed at the outer layer side of the conductive metal layer. The thermoplastic resin film includes a sulfonated thermoplastic resin material forming a sulfonated region of the thermoplastic resin film at the outer film side. The paint coating is disposed on the outer film side of the thermoplastic resin film coincident with the sulfonated region.

Abstract: A method for applying a sulfonation treatment to a thermoplastic part includes forming a sulfonation barrier on the thermoplastic part by applying a sealant tape onto the thermoplastic part, applying a sulfonation fluid to a portion of a thermoplastic surface of the thermoplastic part to sulfonate the thermoplastic part at the thermoplastic surface, removing the sulfonation fluid from the portion of the thermoplastic surface, applying a neutralizing agent to the portion of the thermoplastic surface, washing the portion of the thermoplastic surface, and applying at least one coating to the portion of the thermoplastic surface.

Abstract: A method for applying a sulfonation treatment to a thermoplastic part includes installing a gas sulfonation assembly on one or more surfaces of the thermoplastic part by forming a vacuum bag on the one or more surfaces. The vacuum bag forms a sealed cavity between the vacuum bag and a treatment portion of the one or more surfaces. The method further includes drawing a vacuum in the sealed cavity with the gas sulfonation assembly, directing a sulfonating gas into the sealed cavity with the gas sulfonation assembly to sulfonate the treatment portion, removing the sulfonating gas from the sealed cavity with the gas sulfonation assembly, removing the gas sulfonation assembly from the thermoplastic part, applying a neutralizing agent to the treatment portion, and applying at least one coating to the treatment portion.

Abstract: A process for identifying improvements in a plant may include obtaining operating data associated with multiple devices in the plant. The process may also include performing at least one calculation relative to the operating data using one or more algorithms. The process may further include normalizing the at least one calculation to obtain normalized values. The process may also include identifying a first device of the plurality of devices that has an issue using the normalized values. The process may further include presenting at least one action for a user to undertake to address the issue via a user interface.

Abstract: Systems and methods for using machine learning to assess thermal endurance characteristics, such as relative thermal indices (RTIs), for materials are disclosed. According to certain aspects, an electronic device may train a machine learning model using a set of training data that comprises coordinates indicative of a plurality of characteristics for a plurality of materials, and is labeled with at least one thermal endurance characteristic for each of the plurality of materials. The trained machine learning model may analyze a set of coordinates associated with a candidate material, and output at least one thermal endurance characteristic for that candidate material. The machine learning model may also be continuously updated and used in subsequent analyses.

Abstract: Embodiments of the present invention provide an improved vascular occlusion device for occlusion of a passageway, cavity, or the like. According to one embodiment, a medical device for occluding a left atrial appendage is provided. The medical device includes a first portion having at least one plane of occlusion that is configured to be positioned outside of the left atrial appendage, and a second portion having at least one plane of occlusion that is configured to be at least partially positioned within a cavity defined by the left atrial appendage.

Abstract: A manufacturing method for manufacturing a welded thermoplastic composite and honeycomb core structure is provided. A thermoplastic composite and honeycomb structure is generated by positioning a first thermoplastic composite skin on a support structure, positioning a first thermoplastic film over the first thermoplastic composite skin, positioning a honeycomb core over the first thermoplastic film, positioning a second thermoplastic film is positioned over the honeycomb core, and positioning a second thermoplastic composite skin over the second thermoplastic film. The second thermoplastic composite skin is ultrasonically welded to the honeycomb core. The thermoplastic composite and honeycomb structure is then flipped over, and the first thermoplastic composite skin is then ultrasonically welded to the honeycomb core.

Abstract: In accordance with at least one aspect of this disclosure, there is provided, an artificial intelligence/machine learning (AI/ML) data aggregation module configured to aggregate and parse electronic data from a plurality of systems (e.g., which system(s) may be based on a site location/building) each including a plurality of assets/devices, for determining one or more analytics (e.g., trends) for the assets/devices. In certain embodiments, the AI/ML aggregation module can be configured to receive system data directly and in real time from each of the plurality of systems through one or more communication channels and media formats.

Abstract: This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt, and/or hydrate, and/or cocrystal, and/or drug combination of the compound) that modulate (e.g., agonizes or partially agonizes) NLRP3 that are useful, e.g., for treating a condition, disease or disorder in which an increase in NLRP3 signaling may correct a deficiency in innate immune activity (e.g., a condition, disease or disorder associated with an insufficient immune response) that contributes to the pathology and/or symptoms and/or progression of the condition, disease or disorder (e.g., cancer) in a subject (e.g., a human). This disclosure also features compositions as well as other methods of using and making the same.

Abstract: A method is provided during which a thermoplastic rib is arranged with a thermoplastic spar. A first flange of the thermoplastic rib is abutted against the thermoplastic spar. The first flange of the thermoplastic rib is ultrasonic welded to the thermoplastic spar using a tilted ultrasonic horn. A centerline of the tilted ultrasonic horn is angularly offset from the first flange of the thermoplastic rib by an acute angle during the ultrasonic welding.

Abstract: The present invention provides compounds of Formula (I), (II) or (III): (I), (II), (III), wherein all of the variables are as defined herein. These compounds are modulators of NLRP3, which may be used as medicaments for the treatment of proliferative disorders, such as cancer in a subject (e.g., a human).

Abstract: Systems, methods, and non-transitory computer readable media may provide a view of geospatial information. A user's selection of a location may be obtained. Characteristic information describing characteristics of the location may be obtained. Activities information describing activities of the location may be obtained. An interface (e.g., user interface, API) enabling presentation of a geospatial view of the activities of the location with respect to the characteristics of the location may be provided.

Abstract: Disclosed herein is methods, systems, and aircraft for performing image analysis for aiding refueling operations. A tanker aircraft includes a camera, a refueling boom, a camera configured to generate a two-dimensional (2D) image of the refueling boom, a processor, and non-transitory computer readable storage media storing code. The code is executable by the processor to perform operations including receiving the two-dimensional (2D) image from the camera, determining 2D keypoints of the refueling boom located within the 2D image based on a predefined point model of the refueling boom, determining a 6 degree-of-freedom (6DOF) pose using the 2D keypoints and the corresponding three-dimensional (3D) space 3D keypoints, optimizing 3D keypoints associated with moveable components of the refueling boom in response to a plurality of boom control parameters to produce optimized 3D keypoints, and estimating a position of a tip of the refueling boom based on the 6DOF pose.

Abstract: Controllers for dry eye treatment apparatus and methods are described herein which generally comprise a patch or strip affixed to the skin of the upper and/or lower eyelids to deliver heat to the one or more meibomian glands contained within the underlying skin. The treatment strip or strips include one or more strips configured to adhere to an underlying region of skin in proximity to one or both eyes of a subject such that the one or more strips allow for the subject to blink naturally without restriction from the one or more patches. A controller is in communication with the one or more strips and is programmable to monitor a temperature of the one or more strips to provide a treatment therapy above a threshold temperature of, e.g., 39° C., and below a maximum temperature of, e.g., 48° C., over a treatment period of 12 minutes.

Abstract: Systems and methods of the present disclosure enable simulation of imaging of resident space objects (RSOs) by one or more space-based image sensors. The simulation includes obtaining a satellite constellation configuration having satellite configuration parameters for at least one satellite in a constellation of satellites. The simulation also includes obtaining an RSO configuration having RSO configuration parameters RSOs. The simulation may use the satellite and RSO configuration parameters to simulate constellation ephemeris data for each of the satellites and RSOs. Based on the position of each RSO and satellite, detectability of each RSO by each satellite is simulated based on a photometry simulation using the satellite configuration parameters, including sensor characteristics of a simulated sensor. Imagery may also be simulated based on an image generation model, the sensor configuration, the photometry simulation and at least one background model.

Abstract: An electronic device with a display and a fingerprint sensor displays a fingerprint enrollment interface and detects, on the fingerprint sensor, a plurality of finger gestures performed with a finger. The device collects fingerprint information from the plurality of finger gestures performed with the finger. After collecting the fingerprint information, the device determines whether the collected fingerprint information is sufficient to enroll a fingerprint of the finger. When the collected fingerprint information for the finger is sufficient to enroll the fingerprint of the finger, the device enrolls the fingerprint of the finger with the device. When the collected fingerprint information for the finger is not sufficient to enroll the fingerprint of the finger, the device displays a message in the fingerprint enrollment interface prompting a user to perform one or more additional finger gestures on the fingerprint sensor with the finger.

Abstract: In a described embodiment, a hybrid quantum-classical computing method including receiving time dependent input data of a dynamical system, transforming a first element of the input data using a plurality of transformation matrices to obtain a set of transformed data, and encoding the transformed data into a quantum circuit by performing a first set of quantum operations is implemented. The quantum circuit includes a plurality of layers, wherein the layers include data encoding layers, feedback layers, and a random transformation layer is implemented. Encoding a measurement feedback from a previous measurement vector into the quantum circuit is implemented by performing a second set of quantum operations. The quantum circuit operates to generate an updated measurement vector and a reservoir state is generated based on the updated measurement vector, a previous reservoir state vector and the input data.

Abstract: An electronic device with a display and a fingerprint sensor displays a fingerprint enrollment interface and detects, on the fingerprint sensor, a plurality of finger gestures performed with a finger. The device collects fingerprint information from the plurality of finger gestures performed with the finger. After collecting the fingerprint information, the device determines whether the collected fingerprint information is sufficient to enroll a fingerprint of the finger. When the collected fingerprint information for the finger is sufficient to enroll the fingerprint of the finger, the device enrolls the fingerprint of the finger with the device. When the collected fingerprint information for the finger is not sufficient to enroll the fingerprint of the finger, the device displays a message in the fingerprint enrollment interface prompting a user to perform one or more additional finger gestures on the fingerprint sensor with the finger.