Patents by Inventor Daniel Orton

Daniel Orton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9651563
    Abstract: Methods and systems for diagnosing or prognosing liver fibrosis in a subject are provided. In some examples, such methods and systems can include detecting liver fibrosis-related molecules in a sample obtained from the subject, comparing expression of the molecules in the sample to controls representing expression values expected in a subject who does not have liver fibrosis or who has non-progressing fibrosis, and diagnosing or prognosing liver fibrosis in the subject when differential expression of the molecules between the sample and the controls is detected. Kits for the diagnosis or prognosis of liver fibrosis in a subject are also provided which include reagents for detecting liver fibrosis related molecules.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: May 16, 2017
    Assignee: Battelle Memorial Institute
    Inventors: Jon M. Jacobs, Kristin E. Burnum-Johnson, Erin M. Baker, Richard D. Smith, Marina A. Gritsenko, Daniel Orton
  • Publication number: 20150323551
    Abstract: Methods and systems for diagnosing or prognosing liver fibrosis in a subject are provided. In some examples, such methods and systems can include detecting liver fibrosis-related molecules in a sample obtained from the subject, comparing expression of the molecules in the sample to controls representing expression values expected in a subject who does not have liver fibrosis or who has non-progressing fibrosis, and diagnosing or prognosing liver fibrosis in the subject when differential expression of the molecules between the sample and the controls is detected. Kits for the diagnosis or prognosis of liver fibrosis in a subject are also provided which include reagents for detecting liver fibrosis related molecules.
    Type: Application
    Filed: July 14, 2015
    Publication date: November 12, 2015
    Applicant: Battelle Memorial Institute
    Inventors: Jon M. Jacobs, Kristin E. Burnum-Johnson, Erin M. Baker, Richard D. Smith, Marina A. Gritsenko, Daniel Orton
  • Patent number: 9134326
    Abstract: Methods and systems for diagnosing or prognosing liver fibrosis in a subject are provided. In some examples, such methods and systems can include detecting liver fibrosis-related molecules in a sample obtained from the subject, comparing expression of the molecules in the sample to controls representing expression values expected in a subject who does not have liver fibrosis or who has non-progressing fibrosis, and diagnosing or prognosing liver fibrosis in the subject when differential expression of the molecules between the sample and the controls is detected. Kits for the diagnosis or prognosis of liver fibrosis in a subject are also provided which include reagents for detecting liver fibrosis related molecules.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 15, 2015
    Assignee: Battelle Memorial Institute
    Inventors: Jon M. Jacobs, Kristin E. Burnum-Johnson, Erin M. Baker, Richard D. Smith, Marina A. Gritsenko, Daniel Orton