Patents by Inventor Daniel Ortuno

Daniel Ortuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Producing Olfactory GPCRs
    Publication number: 20110177522
    Abstract: The subject invention provides a method for producing an olfactory GPCR in a cell. In general, the methods involve introducing an expression cassette containing a promoter operably linked to a nucleic acid encoding an olfactory PCR into a macroglial cell, e.g., a Schwann or oligodendritic cell, and maintaining the cell under conditions suitable for production of the olfactory GPCR. Also provided is a macroglial cell containing a recombinant nucleic acid encoding an olfactory GPCR, methods of screening for modulators of olfactory GPCR activity, and a kit for producing an olfactory GPCR in a macroglial cell. The invention finds most use in research on flavors and fragrances, and, consequently, has a variety of research and industrial applications.
    Type: Application
    Filed: August 20, 2010
    Publication date: July 21, 2011
    Inventors: GENE HUNG, DANIEL ORTUNO, DAVID J. UNETT, JOEL GATLIN
  • METHODS FOR PRODUCING OLFACTORY GPCRS
    Publication number: 20090280487
    Abstract: The subject invention provides a method for producing an olfactory GPCR in a cell. In general, the methods involve introducing an expression cassette containing a promoter operably linked to a nucleic acid encoding an olfactory PCR into a macroglial cell, e.g., a Schwann or oligodendritic cell, and maintaining the cell under conditions suitable for production of the olfactory GPCR. Also provided is a macroglial cell containing a recombinant nucleic acid encoding an olfactory GPCR, methods of screening for modulators of olfactory GPCR activity, and a kit for producing an olfactory GPCR in a macroglial cell. The invention finds most use in research on flavors and fragrances, and, consequently, has a variety of research and industrial applications.
    Type: Application
    Filed: October 22, 2008
    Publication date: November 12, 2009
    Inventors: GENE HUNG, Daniel Ortuno, David J. Unett, Joel Gatlin
  • Methods for Producing Olfactory Gpcrs
    Publication number: 20080009015
    Abstract: The subject invention provides a method for producing an olfactory GPCR in a cell. In general, the methods involve introducing an expression cassette containing a promoter operably linked to a nucleic acid encoding an olfactory PCR into a macroglial cell, e.g., a Schwann or oligodendritic cell, and maintaining the cell under conditions suitable for production of the olfactory GPCR. Also provided is a macroglial cell containing a recombinant nucleic acid encoding an olfactory GPCR, methods of screening for modulators of olfactory GPCR activity, and a kit for producing an olfactory GPCR in a macroglial cell. The invention finds most use in research on flavors and fragrances, and, consequently, has a variety of research and industrial applications.
    Type: Application
    Filed: November 15, 2004
    Publication date: January 10, 2008
    Applicant: Arena Pharmaceuticals, Inc.
    Inventors: Gene Hung, Daniel Ortuno, David Unett, Joel Gatlin
  • Endogenous and non-endogenous versions of human G protein-coupled receptors
    Publication number: 20060240523
    Abstract: The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor and to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.
    Type: Application
    Filed: June 30, 2006
    Publication date: October 26, 2006
    Applicant: Arena Pharmaceuticals, Inc.
    Inventors: Chen Liaw, Derek Chalmers, Dominic Behan, Dominique Maciejewski-Lenior, James Leonard, I-Lin Lin, Daniel Ortuno
  • Endogenous and non-endogenous versions of human G protein-coupled receptors
    Patent number: 7119190
    Abstract: The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor and to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: October 10, 2006
    Assignee: Arena Pharmaceuticals, Inc.
    Inventors: Chen W. Liaw, Derek T. Chalmers, Dominic P. Behan, Dominique Maciejewski-Lenior, James N. Leonard, I-Lin Lin, Daniel Ortuño
  • Endogenous and non-endogenous versions of human G protein-coupled receptors
    Publication number: 20030023069
    Abstract: The invention disclosed in this patent document relates to transmembrane receptors, more particularly to a human G protein-coupled receptor and to mutated (non-endogenous) versions of the human GPCRs for evidence of constitutive activity.
    Type: Application
    Filed: February 26, 2002
    Publication date: January 30, 2003
    Inventors: Chen W. Liaw, Derek T. Chalmers, Dominic P. Behan, Dominique Maciejewski-Lenior, James N. Leonard, I-Lin Lin, Daniel Ortuno