Patents by Inventor Daniel Osborne

Daniel Osborne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PROCESSING AND TRANSPORTING ORGANS
    Publication number: 20250057150
    Abstract: The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.
    Type: Application
    Filed: November 4, 2024
    Publication date: February 20, 2025
    Applicant: LifeNet Health
    Inventors: Roberto Bracone, Jingsong Chen, Silvia Chen, James A. Clagett, Marilyn Gatin, Daniel Osborne
  • Methods for collecting, processing and transporting tissue grafts
    Patent number: 12133522
    Abstract: The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.
    Type: Grant
    Filed: November 18, 2022
    Date of Patent: November 5, 2024
    Assignee: LifeNet Health
    Inventors: Roberto Bracone, Jingsong Chen, Marilyn Gatin, Silvia Chen, James A. Clagett, Daniel Osborne
  • Isoindolinone inhibitors of the MDM2-P53 interaction and process for making them
    Patent number: 12077526
    Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.
    Type: Grant
    Filed: January 25, 2023
    Date of Patent: September 3, 2024
    Assignees: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Steven Howard, Benjamin David Cons, Jeffrey David St. Denis, Rhian Sara Holvey, Guillaume François Parra, Kim Louise Hirst, Isabelle Anne Lemasson, David John Nash, James Daniel Osborne, Jonas Calleja Priede, Nicholas Paul Richards, Aaron Michael Dumas, Brian Christopher Bishop, David Parry-Jones, Meenakshi Sundaram Shanmugham, Darren James Dixon, Matthew James Gaunt
  • Isoindolinone inhibitors of the MDM2-P53 interaction having anticancer activity
    Patent number: 12071429
    Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: August 27, 2024
    Assignees: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Gianni Chessari, Steven Howard, Ildiko Maria Buck, Benjamin David Cons, Christopher Norbert Johnson, Rhian Sara Holvey, David Charles Rees, Jeffrey David St. Denis, Emiliano Tamanini, Bernard Thomas Golding, Ian Robert Hardcastle, Celine Florence Cano, Duncan Charles Miller, Martin Edward Mäntylä Noble, Roger John Griffin, James Daniel Osborne, Joanne Peach, Arwel Lewis, Kim Louise Hirst, Benjamin Paul Whittaker, David Wyn Watson, Dale Robert Mitchell
  • METHODS FOR COLLECTING AND PROCESSING AUTOGRAFTS, PROCESSED AUTOGRAFTS, KITS FOR COLLECTING AND TRANSPORTING AUTOGRAFTS, AND TOOLS FOR PREPARING AUTOGRAFTS
    Publication number: 20230079283
    Abstract: The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.
    Type: Application
    Filed: November 18, 2022
    Publication date: March 16, 2023
    Applicant: LifeNet Health
    Inventors: Roberto Bracone, Jingsong Chen, Marilyn Gatin, Silvia Chen, James A. Clagett, Daniel Osborne
  • Isoindolinone inhibitors of the MDM2-P53 interaction and process for making them
    Patent number: 11603367
    Abstract: The invention relates to processes for preparing isoindolin-1-one derivatives, and in particular processes for preparing (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid. The invention also relates to crystalline forms of the compound (2S,3S)-3-(4-chlorophenyl)-3-[(1R)-1-(4-chlorophenyl)-7-fluoro-5-[(1S)-1-hydroxy-1-(oxan-4-yl)propyl]-1-methoxy-3-oxo-2,3-dihydro-1H-isoindol-2-yl]-2-methylpropanoic acid and its salts.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: March 14, 2023
    Assignees: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Steven Howard, Jeffrey David St. Denis, Charlotte Mary Griffiths-Jones, Steven Douglas Hiscock, Alan Richard Burns, David Cousin, Kim Louise Hirst, James Daniel Osborne, Jonas Calleja Priede, Aaron Michael Dumas, Brian Christopher Bishop, David Parry-Jones, Jeremy Peter Scott, Meenakshi Sundaram Shanmugham, Peter Richard Mullens, Darren James Dixon, Matthew James Gaunt
  • Methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts
    Patent number: 11533906
    Abstract: The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.
    Type: Grant
    Filed: November 23, 2020
    Date of Patent: December 27, 2022
    Assignee: LIFENET HEALTH
    Inventors: Roberto Bracone, Jingsong Chen, Marilyn Gatin, Silvia Chen, James A. Clagett, Daniel Osborne
  • Isoindolinone inhibitors of the MDM2-P53 interaction having anticancer activity
    Patent number: 11261171
    Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.
    Type: Grant
    Filed: November 12, 2019
    Date of Patent: March 1, 2022
    Assignees: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Gianni Chessari, Steven Howard, Ildiko Maria Buck, Benjamin David Cons, Christopher Norbert Johnson, Rhian Sara Holvey, David Charles Rees, Jeffrey David St. Denis, Emiliano Tamanini, Bernard Thomas Golding, Ian Robert Hardcastle, Celine Florence Cano, Duncan Charles Miller, Martin Edward Mäntylä Noble, Roger John Griffin, James Daniel Osborne, Joanne Peach, Arwel Lewis, Kim Louise Hirst, Benjamin Paul Whittaker, David Wyn Watson, Dale Robert Mitchell
  • Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity
    Patent number: 10981898
    Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.
    Type: Grant
    Filed: August 8, 2019
    Date of Patent: April 20, 2021
    Assignees: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Gianni Chessari, Steven Howard, Ildiko Maria Buck, Benjamin David Cons, Christopher Norbert Johnson, Rhian Sara Holvey, David Charles Rees, Jeffrey David St. Denis, Emiliano Tamanini, Bernard Thomas Golding, Ian Robert Hardcastle, Celine Florence Cano, Duncan Charles Miller, Martin Edward Mäntylä Noble, Roger John Griffin, James Daniel Osborne, Joanne Peach, Arwel Lewis, Kim Louise Hirst, Benjamin Paul Whittaker, David Wyn Watson, Dale Robert Mitchell
  • METHODS FOR COLLECTING AND PROCESSING AUTOGRAFTS, PROCESSED AUTOGRAFTS, KITS FOR COLLECTING AND TRANSPORTING AUTOGRAFTS, AND TOOLS FOR PREPARING AUTOGRAFTS
    Publication number: 20210084890
    Abstract: The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.
    Type: Application
    Filed: November 23, 2020
    Publication date: March 25, 2021
    Inventors: Roberto Bracone, Jingsong Chen, Marilyn Gatin, Silvia Chen, James A. Clagett, Daniel Osborne
  • Methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts
    Patent number: 10856545
    Abstract: The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: December 8, 2020
    Assignee: LifeNet Health
    Inventors: Roberto Bracone, Jingsong Chen, Marilyn Gatin, Silvia Chen, James A. Clagett, Daniel Osborne
  • Isoindolinone inhibitors of the MDM2-p53 interaction having anticancer activity
    Patent number: 10544132
    Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: January 28, 2020
    Assignees: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Gianni Chessari, Steven Howard, Ildiko Maria Buck, Benjamin David Cons, Christopher Norbert Johnson, Rhian Sara Holvey, David Charles Rees, Jeffrey David St. Denis, Emiliano Tamanini, Bernard Thomas Golding, Ian Robert Hardcastle, Celine Florence Cano, Duncan Charles Miller, Martin Edward Mäntylä Noble, Roger John Griffin, James Daniel Osborne, Joanne Peach, Arwel Lewis, Kim Louise Hirst, Benjamin Paul Whittaker, David Wyn Watson, Dale Robert Mitchell
  • Isoindolinone inhibitors of the MDM2-P53 interaction having anticancer activity
    Patent number: 10526311
    Abstract: The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: January 7, 2020
    Assignees: ASTEX THERAPEUTICS LIMITED, CANCER RESEARCH TECHNOLOGY LIMITED
    Inventors: Gianni Chessari, Steven Howard, Ildiko Maria Buck, Benjamin David Cons, Christopher Norbert Johnson, Rhian Sara Holvey, David Charles Rees, Jeffrey David St. Denis, Emiliano Tamanini, Bernard Thomas Golding, Ian Robert Hardcastle, Celine Florence Cano, Duncan Charles Miller, Martin Edward Mäntylä Noble, Roger John Griffin, James Daniel Osborne, Joanne Peach, Arwel Lewis, Kim Louise Hirst, Benjamin Paul Whittaker, David Wyn Watson, Dale Robert Mitchell
  • Methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts
    Patent number: 10368542
    Abstract: The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.
    Type: Grant
    Filed: September 18, 2013
    Date of Patent: August 6, 2019
    Assignee: LifeNet Health
    Inventors: Roberto Bracone, Jingsong Chen, Silvia Chen, James A. Clagett, Marilyn Gatin, Daniel Osborne
  • System for recognizing an open or closed hand
    Patent number: 8929612
    Abstract: A system and method are disclosed relating to a pipeline for generating a computer model of a target user, including a hand model of the user's hands, captured by an image sensor in a NUI system. The computer model represents a best estimate of the position of a user's hand or hands and whether the hand or hand is in an open or closed state. The generated hand model may be used by a gaming or other application to determine such things as user gestures and control actions.
    Type: Grant
    Filed: November 18, 2011
    Date of Patent: January 6, 2015
    Assignee: Microsoft Corporation
    Inventors: Anthony Ambrus, Kyungsuk David Lee, Andrew Campbell, David Haley, Brian Mount, Albert Robles, Daniel Osborn, Shawn Wright, Nahil Sharkasi, Dave Hill, Daniel McCulloch, Alexandru Balan
  • System for finger recognition and tracking
    Patent number: 8897491
    Abstract: A system and method are disclosed relating to a pipeline for generating a computer model of a target user, including a hand model of the user's hands and fingers, captured by an image sensor in a NUI system. The computer model represents a best estimate of the position and orientation of a user's hand or hands. The generated hand model may be used by a gaming or other application to determine such things as user gestures and control actions.
    Type: Grant
    Filed: October 19, 2011
    Date of Patent: November 25, 2014
    Assignee: Microsoft Corporation
    Inventors: Anthony Ambrus, Kyungsuk David Lee, Andrew Campbell, David Haley, Brian Mount, Albert Robles, Daniel Osborn, Shawn Wright, Nahil Sharkasi, Dave Hill, Daniel McCulloch
  • Methods for Collecting and Processing Autografts, Processed Autografts, Kits for Collecting and Transporting Autografts, and Tools for Preparing Autografts
    Publication number: 20140017785
    Abstract: The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.
    Type: Application
    Filed: September 18, 2013
    Publication date: January 16, 2014
    Applicant: LifeNet Health
    Inventors: Roberto Bracone, Jingsong Chen, Silvia Chen, James A. Clagett, Marilyn Gatin, Daniel Osborne
  • Methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts
    Patent number: 8541233
    Abstract: The present invention is directed to methods for collecting and processing autografts, processed autografts, kits for collecting and transporting autografts, and tools for preparing autografts. It is also directed to autologous bone grafts, and methods of preparing them.
    Type: Grant
    Filed: June 28, 2010
    Date of Patent: September 24, 2013
    Assignee: LifeNet Health
    Inventors: Roberto Bracone, Jingsong Chen, Silvia Chen, James A. Clagett, Marilyn Gatin, Daniel Osborne
  • SYSTEM FOR FINGER RECOGNITION AND TRACKING
    Publication number: 20120309532
    Abstract: A system and method are disclosed relating to a pipeline for generating a computer model of a target user, including a hand model of the user's hands and fingers, captured by an image sensor in a NUI system. The computer model represents a best estimate of the position and orientation of a user's hand or hands. The generated hand model may be used by a gaming or other application to determine such things as user gestures and control actions.
    Type: Application
    Filed: October 19, 2011
    Publication date: December 6, 2012
    Applicant: MICROSOFT CORPORATION
    Inventors: Anthony Ambrus, Kyungsuk David Lee, Andrew Campbell, David Haley, Brian Mount, Albert Robles, Daniel Osborn, Shawn Wright, Nahil Sharkasi, Dave Hill, Daniel McCulloch
  • SYSTEM FOR RECOGNIZING AN OPEN OR CLOSED HAND
    Publication number: 20120308140
    Abstract: A system and method are disclosed relating to a pipeline for generating a computer model of a target user, including a hand model of the user's hands, captured by an image sensor in a NUI system. The computer model represents a best estimate of the position of a user's hand or hands and whether the hand or hand is in an open or closed state. The generated hand model may be used by a gaming or other application to determine such things as user gestures and control actions.
    Type: Application
    Filed: November 18, 2011
    Publication date: December 6, 2012
    Applicant: MICROSOFT CORPORATION
    Inventors: Anthony Ambrus, Kyungsuk David Lee, Andrew Campbell, David Haley, Brian Mount, Albert Robles, Daniel Osborn, Shawn Wright, Nahil Sharkasi, Dave Hill, Daniel McCulloch, Alexandru Balan