Patents by Inventor Daniel P. Kolk
Daniel P. Kolk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11976337Abstract: This disclosure concerns amplification primers, hybridization assay probes, compositions containing such primers and probes, and associated reagents, kits, and methods, that can be used to analyze samples for the presence of Influenza A virus, Influenza B virus, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B target nucleic acids.Type: GrantFiled: March 23, 2018Date of Patent: May 7, 2024Assignee: GEN-PROBE INCORPORATEDInventors: Matthias Jost, Pamela Douglass, Daniel P. Kolk, Mehrdad R. Majlessi
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Patent number: 10745767Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.Type: GrantFiled: January 25, 2018Date of Patent: August 18, 2020Assignee: GEN-PROBE INCORPORATEDInventors: Jeffrey M. Linnen, Daniel P. Kolk, Janel M. Dockter, Damon K. Getman, Tadashi Yoshimura, Martha K. Ho-Sing-Loy, Reinhold B. Pollner, Leslie A. Stringfellow
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Publication number: 20200048721Abstract: This disclosure concerns amplification primers, hybridization assay probes, compositions containing such primers and probes, and associated reagents, kits, and methods, that can be used to analyze samples for the presence of Influenza A virus, Influenza B virus, Respiratory Syncytial Virus A, and/or Respiratory Syncytial Virus B target nucleic acids.Type: ApplicationFiled: March 23, 2018Publication date: February 13, 2020Applicant: GEN-PROBE INCORPORATEDInventors: Matthias JOST, Pamela DOUGLASS, Daniel P. KOLK, Mehrdad R. MAJLESSI
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Publication number: 20180195136Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.Type: ApplicationFiled: January 25, 2018Publication date: July 12, 2018Inventors: Jeffrey M. LINNEN, Daniel P. KOLK, Janel M. DOCKTER, Damon K. GETMAN, Tadashi YOSHIMURA, Martha K. HO-SING-LOY, Reinhold B. POLLNER, Leslie A. STRINGFELLOW
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Patent number: 9914982Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.Type: GrantFiled: August 14, 2015Date of Patent: March 13, 2018Assignee: GEN-PROBE INCORPORATEDInventors: Jeffrey M. Linnen, Daniel P. Kolk, Janel M. Dockter, Damon K. Getman, Tadashi Yoshimura, Martha K. Ho-Sing-Loy, Reinhold B. Pollner, Leslie A. Stringfellow
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Publication number: 20170130280Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.Type: ApplicationFiled: August 14, 2015Publication date: May 11, 2017Inventors: Jeffrey M. LINNEN, Daniel P. KOLK, Janel M. DOCKTER, Damon K. GETMAN, Tadashi YOSHIMURA, Martha K. HO-SING-LOY, Reinhold B. POLLNER, Leslie A. STRINGFELLOW
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Patent number: 9109264Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.Type: GrantFiled: July 6, 2010Date of Patent: August 18, 2015Assignee: Gen-Probe IncorporatedInventors: Jeffrey M. Linnen, Daniel P. Kolk, Janel M. Dockter, Damon K. Getman, Tadashi Yoshimura, Martha K. Ho-Sing-Loy, Reinhold B. Pollner, Leslie A. Stringfellow
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Patent number: 8541171Abstract: Nucleic acid oligomers specific for human parvovirus B19 genomic DNA are disclosed. An assay for amplifying and detecting human parvovirus B19 nucleic acid in biological specimens is disclosed. Compositions for detecting the presence of parvovirus B19 genomic DNA in human biological specimens are disclosed.Type: GrantFiled: December 12, 2012Date of Patent: September 24, 2013Assignee: Gen-Probe IncorporatedInventors: Steven T. Brentano, Margarita Batranina-Kaminsky, Cynthia S. Hasselkus-Light, Daniel P. Kolk
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Patent number: 8354226Abstract: Nucleic acid oligomers specific for human parvovirus B19 genomic DNA are disclosed. An assay for amplifying and detecting human parvovirus B19 nucleic acid in biological specimens is disclosed. Compositions for detecting the presence of parvovirus B19 genomic DNA in human biological specimens are disclosed.Type: GrantFiled: July 25, 2006Date of Patent: January 15, 2013Assignee: Gen-Probe IncorporatedInventors: Steven T. Brentano, Margarita Batranina-Kaminsky, Cynthia S. Hasselkus-Light, Daniel P. Kolk
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Publication number: 20120115125Abstract: Method of detecting HIV-1 nucleic acids using nucleic acid amplification and a molecular torch hybridization probe. The invented method is characterized by high levels of precision in the quantitation of HIV-1 targets at low copy numbers, and by accurate detection of different HIV-1 subtypes, including M group and O group variants.Type: ApplicationFiled: September 26, 2011Publication date: May 10, 2012Applicant: GEN-PROBE INCORPORATEDInventors: Astrid R.W. SCHRODER, Glenn J. SAWYER, Daniel P. KOLK
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Publication number: 20110081645Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.Type: ApplicationFiled: July 6, 2010Publication date: April 7, 2011Applicant: GEN-PROBE INCORPORATEDInventors: Jeffrey M. LINNEN, Daniel P. KOLK, Janel M. DOCKTER, Damon K. GETMAN, Tadashi YOSHIMURA, Martha K. HO-SING-LOY, Reinhold B. POLLNER, Leslie A. STRINGFELLOW
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Patent number: 7785844Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.Type: GrantFiled: October 15, 2007Date of Patent: August 31, 2010Assignee: Gen-Probe IncorporatedInventors: Jeffrey M. Linnen, Daniel P. Kolk, Janel M. Dockter, Damon K. Getman, Tadashi Yoshimura, Martha K. Ho-Sing-Loy, Reinhold B. Pollner, Leslie A. Stringfellow
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Patent number: 7696337Abstract: The present invention is directed to novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength and using the product of one cycle in the next one). In particular, the present invention discloses a method of nucleic acid amplification which is robust and efficient, while reducing the appearance of side products. The method uses only one primer, the “priming oligonucleotide,” a 3?blocked promoter oligonucleotide and optionally, a means for terminating a primer extension reaction, to amplify RNA or DNA molecules in vitro, while reducing or eliminating the formation of side products. The method of the present invention minimizes or eliminates the emergence of side products, thus providing a high level of specificity.Type: GrantFiled: August 26, 2005Date of Patent: April 13, 2010Assignee: Gen-Probe IncorporatedInventors: Michael M. Becker, Steven T. Brentano, Daniel P. Kolk, Wai-Chung Lam, Kristin W. Livezey, Norman C. Nelson, Astrid R. W. Schroder, Gary P. Schroth
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Publication number: 20080274449Abstract: Nucleic acid oligomers specific for human parvovirus B19 genomic DNA are disclosed. An assay for amplifying and detecting human parvovirus B19 nucleic acid in biological specimens is disclosed. Compositions for detecting the presence of parvovirus B19 genomic DNA in human biological specimens are disclosed.Type: ApplicationFiled: July 25, 2006Publication date: November 6, 2008Applicant: GEN-PROBE INCORPORATEDInventors: Steven T. Brentano, Margarita Batranina-Kaminsky, Cynthia S. Hasselkus-Light, Daniel P. Kolk
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Patent number: 7374885Abstract: The present invention is directed to novel methods of synthesizing multiple copies of a target nucleic acid sequence which are autocatalytic (i.e., able to cycle automatically without the need to modify reaction conditions such as temperature, pH, or ionic strength and using the product of one cycle in the next one). In particular, the present invention discloses a method of nucleic acid amplification which is robust and efficient, while reducing the appearance of side-products. The method uses only one primer, the “priming oligonucleotide,” a promoter oligonucleotide modified to prevent polymerase extension from its 3?-terminus and, optionally, a means for terminating a primer extension reaction, to amplify RNA or DNA molecules in vitro, while reducing or substantially eliminating the formation of side-products. The method of the present invention minimizes or substantially eliminates the emergence of side-products, thus providing a high level of specificity.Type: GrantFiled: August 26, 2005Date of Patent: May 20, 2008Assignee: Gen-Probe IncorporatedInventors: Michael M. Becker, Wai-Chung Lam, Kristin W. Livezey, Steven T. Brentano, Daniel P. Kolk, Astrid R. W. Schroder
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Patent number: 7094541Abstract: Nucleic acid oligomers specific for human parvovirus B19 genomic DNA are disclosed. An assay for amplifying and detecting human parvovirus B19 nucleic acid in biological specimens is disclosed. Compositions for detecting the presence of parvovirus B19 genomic DNA in human biological specimens are disclosed.Type: GrantFiled: August 30, 2002Date of Patent: August 22, 2006Assignee: Gen-Probe IncorporatedInventors: Steven T. Brentano, Margarita Batranina-Kaminsky, Cynthia S. Hasselkus-Light, Daniel P. Kolk
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Publication number: 20040029111Abstract: Compositions, methods and kits for detecting viral nucleic acids. Targets that can be detected in accordance with the invention include HBV and/or HIV-1 and/or HCV nucleic acids. Particularly described are oligonucleotides that are useful as hybridization probes and amplification primers that facilitate detection of very low levels of HBV nucleic acids.Type: ApplicationFiled: June 13, 2003Publication date: February 12, 2004Inventors: Jeffrey M. Linnen, Daniel P. Kolk, Janel M. Dockter, Damon K. Getman, Tadashi Yoshimura, Martha K. Ho-Sing-Loy, Reinhold B. Pollner, Leslie A. Stringfellow
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Publication number: 20030124578Abstract: Nucleic acid oligomers specific for human parvovirus B19 genomic DNA are disclosed. An assay for amplifying and detecting human parvovirus B19 nucleic acid in biological specimens is disclosed. Compositions for detecting the presence of parvovirus B19 genomic DNA in human biological specimens are disclosed.Type: ApplicationFiled: August 30, 2002Publication date: July 3, 2003Inventors: Steven T. Brentano, Margarita Batranina-Kaminsky, Cynthia S. Hasselkus-Light, Daniel P. Kolk