Patents by Inventor Daniel P. Magparangalan

Daniel P. Magparangalan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic route to 14-hydroxyl opiates through 1-halo-thebaine or analogs
    Patent number: 8067597
    Abstract: Novel methods of synthesis of known and novel 14-hydroxyl opiates through 1-halothebaine and derivatives are described.
    Type: Grant
    Filed: May 22, 2006
    Date of Patent: November 29, 2011
    Assignee: Mallinckrodt LLC
    Inventors: Peter X. Wang, Frank W. Moser, Gary L. Cantrell, Daniel P. Magparangalan, Jian Bao
  • Opiate intermediates and methods of synthesis
    Patent number: 7834184
    Abstract: Novel opiate intermediate compositions and methods of synthesis that include changing the substitution pattern on the aromatic ring of the pre-Grewe intermediate are provided. The intermediates are morphinane derivatives of formula (10), wherein X is a F or Cl and R is selected from the group consisting of an H, alkyl, aryl, acyl, formyl, COR?, CONHR?, COOR, Bn(benzyl), alkyl(methyl), and sulfonamide SO2CH2COPh.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: November 16, 2010
    Assignee: Mallinckrodt Inc.
    Inventors: Peter Xianqi Wang, Frank W. Moser, Gary L. Cantrell, Daniel P. Magparangalan
  • Synthetic Route to 14-Hydroxyl Opiates Through 1-Halo-Thebaine or Analogs
    Publication number: 20080207906
    Abstract: Novel methods of synthesis of known and novel 14-hydroxyl opiates through 1-halothebaine and derivatives are described.
    Type: Application
    Filed: May 22, 2006
    Publication date: August 28, 2008
    Inventors: Peter X. Wang, Frank W. Moser, Gary L. Cantrell, Daniel P. Magparangalan, Jian Bao
  • Method for the catalytic production of hydrocodone, hydromorphone, and derivatives thereof
    Patent number: 7399858
    Abstract: A method for the catalytic production of hydrocodone derivatives and hydromorphone derivatives, respectively, utilizing a transition metal catalyst of the formula [M(PR4R5R6)nXm]p; wherein M is a Group VIII transition metal; R4, R5 and R6 are selected from the group consisting of alkyl, aryl, alkoxyl, phenoxy and combinations thereof; X is a halide or an anion; n is 1, 2, 3 or 4; m is 1 or 2; and p is at least 1.
    Type: Grant
    Filed: March 7, 2006
    Date of Patent: July 15, 2008
    Assignee: Mallinckrodt Inc.
    Inventors: Peter X. Wang, Frank W. Moser, Gary L. Cantrell, Daniel P. Magparangalan, Jian Bao