Patents by Inventor Daniel P. UCCELLO

Daniel P. UCCELLO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl sulfone-based conjugation handles, methods for their preparation, and their use in synthesizing antibody drug conjugates
    Patent number: 11712480
    Abstract: The present invention is directed to novel heteroaryl sulfone-based conjugation handles of the formula: (wherein R1, R2, Het, D, E, X, Y, Z, m, n, p, q, r, s and t are as defined herein), methods for their preparation, their use in synthesizing antibody drug conjugates, and the resulting antibody drug conjugates made with components having heteroaryl sulfone-based conjugation handles.
    Type: Grant
    Filed: July 31, 2017
    Date of Patent: August 1, 2023
    Assignee: Pfizer Inc.
    Inventors: Russell George Dushin, Daniel P. Uccello, Jeremy Starr, Ye Che, Mark Flanagan, Jeffrey M. Casavant, Christopher John O'Donnell, Gary Frederick Filzen, Jennifer Young, Joseph A. Abramite, Lawrence N. Tumey, Ludivine Moine, Adam Matthew Gilbert, Lee R. Roberts
  • HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES
    Publication number: 20210308276
    Abstract: The present invention is directed to novel heteroaryl sulfone-based conjugation handles of the formula: (wherein R1, R2, Het, D, E, X, Y, Z, m, n, p, q, r, s and t are as defined herein), methods for their preparation, their use in synthesizing antibody drig conjugates, and the resulting antibody drig conjugates made with components having heteroaryl sulfone-based conjugation handles.
    Type: Application
    Filed: July 31, 2017
    Publication date: October 7, 2021
    Applicant: PFIZER INC.
    Inventors: Russell George DUSHIN, Daniel P. UCCELLO, Jeremy STARR, Ye CHE, Mark FLANAGAN, Jeffrey M. CASAVANT, Christopher John O'DONNELL, Gary Frederick FILZEN, Jennifer YOUNG, Joseph A. ABRAMITE, Lawrence N. TUMEY, Ludivine MOINE, Adam Matthew GILBERT, Lee R. ROBERTS