Patents by Inventor Daniel P. Welch

Daniel P. Welch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240101952
    Abstract: Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.
    Type: Application
    Filed: November 30, 2023
    Publication date: March 28, 2024
    Inventors: Daniel P. WELCH, John R. WILSON
  • Patent number: 11891595
    Abstract: Improved cell culture devices and related methods that overcome the limitations of prior devices and methods, by creating devices that can integrate a variety of novel attributes. These various attributes include the use of gas permeable material and medium volumes that exceed conventional devices as well as compartments that can facilitate the long term study of high density cultures with reduced disruption of the culture environment, the ability to study the migration of items of interest including substances such as chemokine, track the movement of cells, and monitor cell to cell interactions.
    Type: Grant
    Filed: March 24, 2023
    Date of Patent: February 6, 2024
    Assignee: Wilson Wolf Manufacturing LLC
    Inventors: John R. Wilson, Daniel P. Welch
  • Patent number: 11873474
    Abstract: Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.
    Type: Grant
    Filed: September 16, 2021
    Date of Patent: January 16, 2024
    Assignee: Wilson Wolf Manufacturing
    Inventors: Daniel P. Welch, John R. Wilson
  • Publication number: 20230227762
    Abstract: Improved cell culture devices and related methods that overcome the limitations of prior devices and methods, by creating devices that can integrate a variety of novel attributes. These various attributes include the use of gas permeable material and medium volumes that exceed conventional devices as well as compartments that can facilitate the long term study of high density cultures with reduced disruption of the culture environment, the ability to study the migration of items of interest including substances such as chemokine, track the movement of cells, and monitor cell to cell interactions.
    Type: Application
    Filed: March 24, 2023
    Publication date: July 20, 2023
    Inventors: John R. Wilson, Daniel P. Welch
  • Patent number: 11613725
    Abstract: Improved cell culture devices and related methods that overcome the limitations of prior devices and methods, by creating devices that can integrate a variety of novel attributes. These various attributes include the use of gas permeable material and medium volumes that exceed conventional devices as well as compartments that can facilitate the long term study of high density cultures with reduced disruption of the culture environment, the ability to study the migration of items of interest including substances such as chemokine, track the movement of cells, and monitor cell to cell interactions.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: March 28, 2023
    Assignee: Wilson Wolf Manufacturing
    Inventors: John R. Wilson, Daniel P. Welch
  • Publication number: 20220002659
    Abstract: Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.
    Type: Application
    Filed: September 16, 2021
    Publication date: January 6, 2022
    Inventors: Daniel P. Welch, John R. Wilson
  • Patent number: 11155778
    Abstract: Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: October 26, 2021
    Assignee: Wilson Wolf Manufacturing
    Inventors: Daniel P. Welch, John R. Wilson
  • Publication number: 20180037864
    Abstract: Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.
    Type: Application
    Filed: October 5, 2017
    Publication date: February 8, 2018
    Inventors: Daniel P. Welch, John R. Wilson
  • Patent number: 9840692
    Abstract: Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: December 12, 2017
    Assignee: Wilson Wolf Manufacturing
    Inventors: Daniel P. Welch, John R. Wilson
  • Publication number: 20160326478
    Abstract: Improved cell culture devices and related methods that overcome the limitations of prior devices and methods, by creating devices that can integrate a variety of novel attributes. These various attributes include the use of gas permeable material and medium volumes that exceed conventional devices as well as compartments that can facilitate the long term study of high density cultures with reduced disruption of the culture environment, the ability to study the migration of items of interest including substances such as chemokine, track the movement of cells, and monitor cell to cell interactions.
    Type: Application
    Filed: May 9, 2016
    Publication date: November 10, 2016
    Inventors: John R. Wilson, Daniel P. Welch
  • Patent number: 8999703
    Abstract: This invention relates to methods and devices that improve the process of culturing cells and/or shipping cells from one location to another. They have the capacity to reduce the risk of contamination, regulate pressure in the medium surrounding cells, and maintain cells in a uniform distribution throughout transit. This leads to an improved level of process control relative to current methods.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: April 7, 2015
    Inventors: Daniel P. Welch, John R. Wilson
  • Publication number: 20140377739
    Abstract: Novel methods and apparatus are disclosed for cell culture and cell recovery. The methods and apparatus simplify the process of cell separation from media, minimize potential damage to gas permeable devices during fluid handling, and allow closed system automated cell culture and cell recovery from gas permeable devices.
    Type: Application
    Filed: June 24, 2014
    Publication date: December 25, 2014
    Inventors: Daniel P. Welch, John R. Wilson
  • Patent number: 8697443
    Abstract: Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture efficiency and scale up efficiency.
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: April 15, 2014
    Assignee: Wilson Wolf Manufacturing Corporation
    Inventors: John R. Wilson, Douglas A. Page, Daniel P. Welch, Alison Robeck
  • Patent number: 8501468
    Abstract: A versatile compartmentalized cell culture device, with a selectively permeable membrane separating the compartments, provides many attributes relative to traditional devices. It can be configured for high-density cell culture, co-culture, and sample dialysis while rolling or standing still. It can also be configured for continuous movement of liquid between compartments. The wide combination of attributes not found in other membrane based cell culture and bioprocessing devices includes more cell capacity, more cell secreted product capacity, higher cell and product density, increased medium capacity, minimized use of exogenous growth factors, compatibility with standard cell culture equipment and protocols, increased scale up efficiency, capacity to function when rolling or standing still, capacity for perfusion without the need for pumps, and more efficient sample dialysis.
    Type: Grant
    Filed: March 1, 2010
    Date of Patent: August 6, 2013
    Assignee: Wheaton Industries, Inc.
    Inventors: John R. Wilson, Daniel P. Welch, Alison Robeck, Douglas A. Page
  • Publication number: 20110212519
    Abstract: A versatile compartmentalized cell culture device, with a selectively permeable membrane separating the compartments, provides many attributes relative to traditional devices. It can be configured for high-density cell culture, co-culture, and sample dialysis while rolling or standing still. It can also be configured for continuous movement of liquid between compartments. The wide combination of attributes not found in other membrane based cell culture and bioprocessing devices includes more cell capacity, more cell secreted product capacity, higher cell and product density, increased medium capacity, minimized use of exogenous growth factors, compatibility with standard cell culture equipment and protocols, increased scale up efficiency, capacity to function when rolling or standing still, capacity for perfusion without the need for pumps, and more efficient sample dialysis.
    Type: Application
    Filed: March 1, 2010
    Publication date: September 1, 2011
    Inventors: John R. Wilson, Daniel P. Welch, Alison Robeck, Douglas A. Page
  • Publication number: 20110008877
    Abstract: An apparatus for shipping, storing, and viewing a cornea. The device offers an improvement to cornea health relative to conventional cornea containers.
    Type: Application
    Filed: June 17, 2010
    Publication date: January 13, 2011
    Applicant: WILSON WOLF MANUFACTURING
    Inventors: Debra Skelnik, Roger Wilson, Daniel P. Welch, John R. Wilson
  • Publication number: 20100255576
    Abstract: Gas permeable devices and methods are disclosed for cell culture, including cell culture devices and methods that contain medium at heights, and certain gas permeable surface area to medium volume ratios. These devices and methods allow improvements in cell culture efficiency and scale up efficiency.
    Type: Application
    Filed: April 2, 2010
    Publication date: October 7, 2010
    Inventors: John R. Wilson, Douglas A. Page, Daniel P. Welch, Alison Robeck
  • Patent number: 7799560
    Abstract: A versatile compartmentalized cell culture device, with a selectively permeable membrane separating the compartments, provides many attributes relative to traditional devices. It can be configured for high-density cell culture, co-culture, and sample dialysis while rolling or standing still. It can also be configured for continuous movement of liquid between compartments. The wide combination of attributes not found in other membrane based cell culture and bioprocessing devices includes more cell capacity, more cell secreted product capacity, higher cell and product density, increased medium capacity, minimized use of exogenous growth factors, compatibility with standard cell culture equipment and protocols, increased scale up efficiency, capacity to function when rolling or standing still, capacity for perfusion without the need for pumps, and more efficient sample dialysis.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: September 21, 2010
    Assignee: Wilson Wolf Manufacturing Corporation
    Inventors: John R. Wilson, Daniel P. Welch, Alison Robeck, Douglas A. Page
  • Publication number: 20090272748
    Abstract: This invention relates to methods and devices that improve the process of culturing cells and/or shipping cells from one location to another. They have the capacity to reduce the risk of contamination, regulate pressure in the medium surrounding cells, and maintain cells in a uniform distribution throughout transit. This leads to an improved level of process control relative to current methods.
    Type: Application
    Filed: May 5, 2008
    Publication date: November 5, 2009
    Inventors: Daniel P. Welch, John R. Wilson, Klearchos K. Papas, Efstathios S. Avgoustiniatos
  • Patent number: D596476
    Type: Grant
    Filed: July 27, 2007
    Date of Patent: July 21, 2009
    Inventor: Daniel P. Welch