Patents by Inventor Daniel Pan

Daniel Pan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for drug delivery
    Patent number: 11123441
    Abstract: Compositions comprising a red blood cell (RBC) having non-toxically coupled thereto a nanoparticle having a low shear modulus or low Young's modulus of less than 10 MPa and containing a drug are provided. In one embodiment, the nanoparticles are optionally coated with protein. In another embodiment, the nanoparticle has no cell-specific targeting moiety or tissue-specific targeting moiety or organ-specific targeting moiety associated therewith. Methods of delivering selected drugs to target organs use these compositions both in vivo and ex vivo treatment of disease and for imaging.
    Type: Grant
    Filed: October 2, 2017
    Date of Patent: September 21, 2021
    Assignees: The Trustees of the University of Pennsylvania, The Regents of the University of California
    Inventors: Vladimir Muzykantov, Jacob Brenner, Jacob Myerson, Daniel Pan, Samir Suresh Mitragotri
  • METHODS AND COMPOSITIONS FOR DRUG DELIVERY
    Publication number: 20180243440
    Abstract: Compositions comprising a red blood cell (RBC) having non-toxically coupled thereto a nanoparticle having a low shear modulus or low Young's modulus of less than 10 MPa and containing a drug are provided. In one embodiment, the nanoparticles are optionally coated with protein. In another embodiment, the nanoparticle has no cell-specific targeting moiety or tissue-specific targeting moiety or organ-specific targeting moiety associated therewith. Methods of delivering selected drugs to target organs use these compositions both in vivo and ex vivo treatment of disease and for imaging.
    Type: Application
    Filed: October 2, 2017
    Publication date: August 30, 2018
    Inventors: Vladimir Muzykantov, Jacob Brenner, Jacob Myerson, Daniel Pan