Patents by Inventor Daniel Paone

Daniel Paone has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MRGX2 ANTAGONISTS
    Publication number: 20220112174
    Abstract: This invention relates to novel compounds according to Formula (I) which are antagonists of MrgX2, to pharmaceutical compositions containing them, and to their use in therapy for the treatment of MrgX2-mediated diseases and disorders.
    Type: Application
    Filed: October 4, 2021
    Publication date: April 14, 2022
    Inventors: Edward BRNARDIC, Michael BURY, Rodolfo CADILLA, Jon COLLINS, Yu GUO, Anthony HANDLON, Huijie LI, Yue LI, Daniel PAONE, Christie SCHULTE, Barry SHEARER, Guosen YE, Maben YING, Huichang ZHANG
  • P2X3 RECEPTOR ANTAGONISTS FOR TREATMENT OF PAIN
    Publication number: 20110003822
    Abstract: The subject invention relates to novel P2X3 receptor antagonists that play a critical role in treating disease states associated with pain, in particular peripheral pain, inflammatory pain, or tissue injury pain that can be treated using a P2X3 receptor subunit modulator.
    Type: Application
    Filed: October 29, 2008
    Publication date: January 6, 2011
    Inventors: Christopher S. Burgey, Diem N. Nguyen, Daniel Paone, Craig M. Potteiger, Joseph P. Vacca
  • Cgrp Receptor Antagonists
    Publication number: 20080090806
    Abstract: The present invention is directed to compounds of Formula (I) and Formula (II) (where variables R1, R2, R3, R4, A, B, G, J, Q, T, U, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: October 18, 2005
    Publication date: April 17, 2008
    Inventors: Daniel Paone, Diem Nguyen, Christopher Burgey, James Deng
  • Cgrp Receptor Antagonists
    Publication number: 20070287696
    Abstract: Compounds of Formula I: and Formula II: (where variables R1, R2, R3, R4, A, B, D, G, J, Q, T, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, pharmaceutical compositions comprising these compounds, use of these compounds and compositions to prevent or treat diseases involving CGRP.
    Type: Application
    Filed: January 25, 2005
    Publication date: December 13, 2007
    Inventors: Christopher Burgey, Daniel Paone, Anthony Shaw, Craig Stump, Theresa Williams
  • Cgrp Receptor Antagonists
    Publication number: 20070287697
    Abstract: Compounds of Formula (I) and Formula (II) (where variables R1, R2, R4, A, B, W, X, Y and Z are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: October 12, 2005
    Publication date: December 13, 2007
    Inventors: Daniel Paone, Anthony Shaw, Craig Potteiger
  • CGRP receptor antagonists
    Publication number: 20070225272
    Abstract: The present invention is directed to compounds of Formula I: and Formula II: (where variables R1, R2, R3, R4, A, B, G, J, Q, T, U, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: March 14, 2007
    Publication date: September 27, 2007
    Inventors: Christopher Burgey, Zhengwu Deng, Diem Nguyen, Daniel Paone, Anthony Shaw, Theresa Williams
  • Cgrp receptor antagonists
    Publication number: 20060194783
    Abstract: The present invention is directed to compounds of Formula I and Formula II: (where variables R1, R2, R3, R4, R6, A, B, G, J, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: April 9, 2004
    Publication date: August 31, 2006
    Inventors: Christopher Burgey, Daniel Paone, Anthony Shaw, Theresa Williams
  • CGRP receptor antagonists
    Publication number: 20050256098
    Abstract: The present invention is directed to compounds of Formula I: and Formula II: (where variables R1, R2, R3, R4, A, B, G, J, Q, T, U, V, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
    Type: Application
    Filed: June 14, 2005
    Publication date: November 17, 2005
    Inventors: Christopher Burgey, Zhengwu Deng, Diem Nguyen, Daniel Paone, Anthony Shaw, Theresa Williams