Abstract: The present invention relates to frameworks and methodologies configured to enable support and delivery of a multimedia messaging interface, including (but not limited to) automated content generation and classification, content search and prioritisation, and data analytics. Some embodiments relate to frameworks and methodologies configured to enable generation of and management of content items, which are optionally made available via a messaging interface, via media artefact identification (for example based on contextual data, audio, text and/or object recognition). Examples include technology that enables automated generation and categorisation of sub-clips from one or more media source files.

Abstract: Methods and materials are described for producing immortalized hybrid cells composed of a fusion of immortalized multi-lineage progenitor cells (MLPC) and primary hepatocytes. The hybrid cells express the biological activity of the primary hepatocytes and the immortality and expansion capacities of the immortalized MLPC. The methods of culture and expansion of the resultant hybrid cells and the methods to confirm the characteristics of the hybrid cells are described.

Abstract: Culture medium formulations are described that are capable of large-scale expansion of stem cell-derived hepatocyte-like cells while sustaining the activity of those cells to maintain the phenotype and biological characteristics of normal hepatocytes.

Abstract: The present invention generally relates to compositions, systems and methods that detect and/or remove cross-reactive antibodies from a biological sample. In many cases, the cross-reactive antibodies are human anti-animal antibodies. In certain cases, the cross-reactive antibodies are human anti-mouse antibodies.

Abstract: The invention provides systems, methods, compositions, and separation media for cell separation and for the concentration of therapeutically important cells from blood cell containing tissues. The systems, methods, reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover even rare cell types in high yield.

Abstract: Embodiments provide a cell separation composition and methods for separating and recovering desired therapeutic cells in a blood tissue sample.

Abstract: The present invention generally relates to compositions, systems and methods that detect and/or remove cross-reactive antibodies from a biological sample. In many cases, the cross-reactive antibodies are human anti-animal antibodies. In certain cases, the cross-reactive antibodies are human anti-mouse antibodies.