Patents by Inventor Daniel Patrick Walker

Daniel Patrick Walker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Positive allosteric modulators of the nicotinic acetylcholine receptor
    Publication number: 20040249150
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: June 29, 2004
    Publication date: December 9, 2004
    Applicant: Pfizer Inc
    Inventors: David W. Piotrowski, Bruce N. Rogers, William W. McWhorter, Daniel Patrick Walker, Jeffrey W. Corbett, Vincent E. Groppi, Daniel G. Rudmann
  • Quinuclidine-substituted hetero-bicyclic aromatic compounds for the treatment of disease
    Patent number: 6828330
    Abstract: The invention provides compounds of Formula I: wherein W0 is a bicyclic moiety and is These compounds may be in the form of pharmaceutical salts or compositions, may be in pure enantiomeric form or racemic mixtures, and are useful to treat diseases or conditions in which &agr;7 is known to be involved.
    Type: Grant
    Filed: June 6, 2002
    Date of Patent: December 7, 2004
    Assignee: Pharmacia & Upjohn Company
    Inventors: Daniel Patrick Walker, Donn G. Wishka, David W. Piotrowski, Vincent E. Groppi, Jr.
  • Azabicyclic compounds for the treatment of disease
    Publication number: 20040224976
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: June 15, 2004
    Publication date: November 11, 2004
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Vincent E. Groppi
  • Quinuclidine-substituted hetero-bicyclic aromatic compounds for the treatment of disease
    Publication number: 20040224977
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: June 10, 2004
    Publication date: November 11, 2004
    Inventors: Daniel Patrick Walker, Donn G. Wishka, Jeffrey W. Corbett, Mark R. Rauckhorst, David W. Piotrowski, Vincent E. Groppi
  • Compounds as radioligands for the diagnosis of disease
    Publication number: 20040157878
    Abstract: Radiolabeled ligands useful as probes for determining the relative abundance, receptor occupancy, and/or function of nicotinic acetylcholine receptors. The compounds of Formula I as described herein are labeled with a radioactive isotopic moiety such as 11C, 18F, 76Br, 123I or 125I. Disorders are diagnosed by administering to a mammal a detectably labeled compound and detecting the binding of that compound to the nAChR. The compounds that have been administered are detected using methods including, but not limited to, position emission topography and single-photon emission computed tomography. The present invention is useful in diagnosing a wide variety of diseases and disorders as discussed herein.
    Type: Application
    Filed: December 5, 2003
    Publication date: August 12, 2004
    Inventors: Bruce Nelson Rogers, David W. Piotrowski, Vincent Edward Groppi, Eric Jon Jacobsen, Jason Kenneth Myers, Daniel Patrick Walker, Donn Gregory Wishka, Marc Bradley Skaddan
  • Compounds having both alpha7 nicotinic agonist activity and 5HT3 antagonist activity for the treatment of CNS diseases
    Publication number: 20040147522
    Abstract: The invention discloses compounds that are selective &agr;7 nAChR agonists and 5-HT3 antagonists. The compounds are useful for treating many CNS diseases.
    Type: Application
    Filed: October 31, 2003
    Publication date: July 29, 2004
    Inventors: Erik Ho Fong Wong, Luz A. Cortes-Burgos, Bruce Nelson Rogers, David W. Piotrowski, Daniel Patrick Walker, Eric Jon Jacobsen, Brad A. Acker, Donn G. Wishka
  • 1H-pyrazole and 1H-pyrrole-azabicyclic compounds for the treatment of disease
    Publication number: 20040087616
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: July 25, 2003
    Publication date: May 6, 2004
    Inventors: David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Daniel Patrick Walker, Donn G. Wishka, Vincent E. Groppi
  • Positive allosteric modulators of the nicotinic acetylcholine receptor
    Publication number: 20030236287
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: April 25, 2003
    Publication date: December 25, 2003
    Inventors: David W. Piotrowski, Bruce N. Rogers, William W. McWhorter, Daniel Patrick Walker, Jeffrey W. Corbett, Vincent E. Groppi, Daniel G. Rudmann
  • Substituted-aryl compounds for treatment of disease
    Publication number: 20030236279
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 10, 2003
    Publication date: December 25, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Jason K. Myers, Vincent E. Groppi
  • Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease
    Publication number: 20030236264
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 14, 2003
    Publication date: December 25, 2003
    Inventors: Bruce N. Rogers, David W. Piotrowski, Daniel Patrick Walker, Eric Jon Jacobsen, Brad A. Acker, Donn G. Wishka, Vincent E. Groppi
  • Azabicyclic compounds for the treatment of disease
    Publication number: 20030236270
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 14, 2003
    Publication date: December 25, 2003
    Inventors: Eric Jon Jacobsen, Jason K. Myers, Daniel Patrick Walker, Donn G. Wishka, Steven Charles Reitz, David W. Piotrowski, Brad A. Acker, Vincent E. Groppi
  • Azabicyclic compounds for the treatment of disease
    Publication number: 20030232853
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: February 13, 2003
    Publication date: December 18, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Vincent E. Groppi
  • Azabicyclic-substituted-heteroaryl compounds for the treatment of disease
    Publication number: 20030207913
    Abstract: The invention provides compounds of Formula I:
    Type: Application
    Filed: November 6, 2002
    Publication date: November 6, 2003
    Inventors: David W. Piotrowski, Jason K. Myers, Bruce N. Rogers, Eric Jon Jacobsen, Alice L. Bodnar, Vincent E. Groppi, Daniel Patrick Walker, Brad A. Acker
  • N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
    Publication number: 20030176702
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: October 17, 2002
    Publication date: September 18, 2003
    Inventors: Daniel Patrick Walker, Eric Jon Jacobsen, David W. Piotrowski, Brad A. Acker, Donn G. Wishka, Jeffrey W. Corbett, Mark R. Rauckhorst, Vincent E. Groppi
  • Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease
    Publication number: 20030153595
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: October 1, 2002
    Publication date: August 14, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Donn G. Wishka, Steven Charles Reitz, Vincent E. Groppi
  • Azabicyclic-phenyl-fused-heterocyclic compounds for treatment of disease
    Publication number: 20030130305
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: November 1, 2002
    Publication date: July 10, 2003
    Inventors: Daniel Patrick Walker, David W. Piotrowski, Eric Jon Jacobsen, Brad A. Acker, Vincent E. Groppi
  • Substituted 7-aza[2.2.1]bicycloheptanes for the treatment of disease
    Publication number: 20030105089
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: September 4, 2002
    Publication date: June 5, 2003
    Inventors: Donn G. Wishka, Daniel Patrick Walker, Jeffrey W. Corbett, Steven Charles Reitz, Mark R. Rauckhorst, Vincent E. Groppi
  • Quinuclidine-substituted hetero-bicyclic aromatic compounds for the treatment of disease
    Publication number: 20030073707
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: June 6, 2002
    Publication date: April 17, 2003
    Inventors: Daniel Patrick Walker, Donn G. Wishka, Jeffrey W. Corbett, Mark R. Rauckhorst, David W. Piotrowski, Vincent E. Groppi
  • Substituted azabicyclic moieties for the treatment of disease
    Publication number: 20030055043
    Abstract: The invention provides compounds of Formula I: 1
    Type: Application
    Filed: April 17, 2002
    Publication date: March 20, 2003
    Inventors: Eric Jon Jacobsen, Daniel Patrick Walker, Jason K. Myers, David W. Piotrowski, Vincent E. Groppi