Abstract: The present invention relates to compounds useful for degrading BTK via a ubiquitin proteolytic pathway. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders.

Abstract: Described herein are techniques are provided for enabling a security orchestration, automation, and response (SOAR) service to automatically manage apps used to interface with an integrated security operations service and other related devices and services. Further described herein is a SOAR app generator service or application used to automate the creation of apps for a SOAR service based on application programming interfaces (API) specifications for related devices or services, as well as visual playbook editor interfaces for a SOAR service that enable the configuration of complex action input parameters including arrays and objects.

Abstract: A layer-by-layer (LbL) system, which alternately ionically complexes anionic AuNPs to two unique cationic polymers (disulfide-reducible and hydrolytically degradable) and two anionic nucleic acids, is disclosed.

Abstract: Control and automation devices and systems for automatically and/or remotely controlling fixtures such as, for example, light fixtures and/or other electrical and/or electronic devices, by controlling, operating, and/or interacting with existing switches, controls, power sources, and/or other components already present in an environment of interest, and methods for their installation and use; conservation of power in wireless devices while providing capacity for power and bandwidth demanding applications such as, for example, video transmission.

Abstract: Control devices for automatically and/or remotely controlling fixtures such as, for example, light fixtures and/or other electrical and/or electronic devices, by controlling, operating, and/or interacting with existing switches, controls, power sources, and/or other components already present in an environment of interest, and methods for their installation and use.

Abstract: Embodiments are disclosed of methods, systems, devices, apparatus, compositions, articles of manufacture, and improvements thereof useful for automatically and/or remotely controlling fixtures such as, for example, light fixtures and/or other electrical and/or electronic devices, by controlling, operating, and/or interacting with existing switches, controls, power sources, and/or other components already present in an environment of interest.

Abstract: An automation device to control a pre-existing light switch is described which attaches to the light switch by internal magnets at locations corresponding to the magnetic screw heads of the light switch. This makes installation a simple process requiring no hand tools or electrical connections be made with the light switch. The automation device can be wired or wirelessly controlled and works with both toggle light switches and rocker light switches. Additional functionalities include various timed and automated operations as well as device and user location determinations.

Abstract: An automation device to control a pre-existing light switch is described which attaches to the light switch by internal magnets at locations corresponding to the magnetic screw heads of the light switch. This makes installation a simple process requiring no hand tools or electrical connections be made with the light switch. The automation device can be wired or wirelessly controlled and works with both toggle light switches and rocker light switches. Additional functionalities include various timed and automated operations as well as device and user location determinations.

Abstract: A layer-by-layer (LbL) system, which alternately ionically complexes anionic AuNPs to two unique cationic polymers (disulfide-reducible and hydrolytically degradable) and two anionic nucleic acids, is disclosed.

Abstract: An embodiment in accordance with the present invention provides a device and method for suturing the fascia or other tissue in a patient. The device includes a first arm and a second arm pivotally coupled to one another and housing a spring-based lever system that is configured to frictionally hold a portion of a needle within each of the first and second arms. A switch allows the spring-based lever system to be used to pass the needle between the first and second arms. When the switch is in a first position, the needle is frictionally held by the spring-based lever system within the first arm and released within the second arm. Likewise, when the switch is in a second position, the needle is frictionally held by the spring-based lever system within the second arm and released within the first arm.