Abstract: An epoxy formulation is provided with improved properties for electrical components exposed to a voltage differential. The improved electrical properties include increased glass transition temperature, increased breakdown strength and/or lower loss factor. Electrical components may be formed from the epoxy formulation by 3D printing the epoxy formulation and curing the formulation with UV radiation. The epoxy formulation includes epoxy, a photoinitiator and an accelerator.

Abstract: Novel compositions and methods are provided for effective clinical management of central nervous system (CNS) cancers in mammalian subjects, including humans. The anti-CNS cancer compositions and methods employ lucanthone, alone or in combination with other anti-CNS cancer drugs or methods (including chemotherapy, such as with temozolomide, and radiation), to prevent or reduce CNS cancer, including gliomas. In certain embodiments, lucanthone compositions and methods effectively treat glioblastomas, including high grade glioblastomas. In other embodiments, lucanthone compositions and methods effectively target and control CNS cancer stem cells, for example to reduce or prevent recurrence of glioblastomas unresolved by conventional treatments.

Abstract: Disclosed herein are compositions and methods employing AMPA Receptor (AMPR) antagonist compounds to treat AMPAR positive cancers in mammalian subjects. In certain detailed embodiments the AMPAR antagonist is a Perampanel compound, effective to mediate potent oncolytic effects to prevent or reduce the severity or recurrence of a variety of cancer forms, including central nervous system (CNS) cancers.

Abstract: Technologies for non-contact displacement control are disclosed. An additive manufacturing system may include a dispenser having a tip configured to deposit an additive material onto a substrate, a transducer coupled to the dispenser and configured to transmit an emitted signal from the dispenser to the substrate, and a sensor coupled to the dispenser and configured to detect a return signal from the substrate to the dispenser, where the return signal is indicative of a distance between the tip of the dispenser and the substrate.

Abstract: A system includes a tool for installing a cable material around a set of elongate members. The tool includes a housing; a cartridge detachably connected to the housing; and a jaw detachably connected to the housing. The cartridge has a length of cable material. The jaw is configured to extend around the set of elongate members to install the length of cable around the set of elongate members. A welding horn is detachably connected to the housing. At least one processor is configured to read a programmable chip. The programmable chip stores a set of parameters for at least one of the cartridge, the jaw, or the welding horn.

Abstract: Electrically resistive devices, such as voltage dividers, and methods of making the same are disclosed. An illustrative voltage divider may include a substrate having an axis, an electrically resistive path applied to the substrate, and at least one terminal positioned around the substrate and in contact with the electrically resistive path. The electrically resistive path may include a primary resistor and a secondary resistor, with the primary resistor having a higher electrical resistance than the secondary resistor. An adjustable displacement of the at least one terminal along the axis of the substrate may allow adjustment of at least one electrical resistance associated with the at least one terminal. An adjustable tightness of the at least one terminal around the substrate may allow adjustment of the at least one electrical resistance associated with the at least one terminal.

Abstract: A push-lock coupler includes an annular metal insert with a coaxial profile complementary to a conduit; a cylindrical polymeric housing molded over the annular metal insert and having a first and second end and an inner surface; and wherein the first and second end are capable of deforming to the coaxial profile of the conduit inserted into either the first or second end, and the inner surface of the cylindrical polymeric housing has at least one groove disposed between the annular metal insert and the first end.

Abstract: A system of additive manufacturing of a high-voltage electronic component is provided. The system includes a dispenser and a height control assembly. The dispenser has a tip configured to deposit an additive material onto a surface of a substrate. The height control assembly is coupled to the dispenser and configured to detect a distance change of the tip of the dispenser from the surface of the substrate, wherein the height control assembly is further configured to adjust the dispenser based on the detected distance change.

Abstract: A system of additive manufacturing of an electronic component is provided. The system includes a deposition control computing device, the deposition control computing device including at least one processor in communication with at least one memory device. The at least one processor is programmed to generate control instructions of additive manufacturing of the electronic component, interpret the control instructions into controls of the system, and output the controls.

Abstract: A system includes a tool for installing a cable material around a set of elongate members. The tool includes a housing; a cartridge detachably connected to the housing; and a jaw detachably connected to the housing. The cartridge has a length of cable material. The jaw is configured to extend around the set of elongate members to install the length of cable around the set of elongate members. A welding horn is detachably connected to the housing. At least one processor is configured to read a programmable chip. The programmable chip stores a set of parameters for at least one of the cartridge, the jaw, or the welding horn.

Abstract: A push-lock coupler includes an annular metal insert with a coaxial profile complementary to a conduit; a cylindrical polymeric housing molded over the annular metal insert and having a first and second end and an inner surface; and wherein the first and second end are capable of deforming to the coaxial profile of the conduit inserted into either the first or second end, and the inner surface of the cylindrical polymeric housing has at least one groove disposed between the annular metal insert and the first end.

Abstract: A system includes a body having a pair of cable jaws. The pair of cable jaws further includes a dispensing track on an inner circumference of the pair of cable jaws to retain a segment of a thermoplastic cable material. The system includes a piston. The piston is configured to secure an overlapping segment of the thermoplastic cable material at the weld area. An induction coil is configured to apply an electromagnetic field. The system includes a power supply.

Abstract: A system and method for forming electrical devices via additive manufacturing processes that utilize starting materials that are in a solid state at least prior to, as well as after, the formation of the electrical device. A first solid starting material can be configured to form one or more insulator layers of the electrical device, while another solid starting material can be applied to form one or more electrically conductive layers. The starting materials canbe applied layer-by-layer during formation of the electrical device such that the electrically conductive layers can become automatically embedded within the insulating layers, and vice versa. The additive manufacturing process(es) utilized to form the electrically conductive layers from solid starting materials can be different than the additive manufacturing process(es) utilized to form the insulator layers.

Abstract: An epoxy formulation is provided with improved properties for electrical components exposed to a voltage differential. The improved electrical properties include increased glass transition temperature, increased breakdown strength and/or lower loss factor. Electrical components may be formed from the epoxy formulation by 3D printing the epoxy formulation and curing the formulation with UV radiation. The epoxy formulation includes epoxy, a photoinitiator and an accelerator.

Abstract: Technologies for non-contact displacement control are disclosed. An additive manufacturing system may include a dispenser having a tip configured to deposit an additive material onto a substrate, a transducer coupled to the dispenser and configured to transmit an emitted signal from the dispenser to the substrate, and a sensor coupled to the dispenser and configured to detect a return signal from the substrate to the dispenser, where the return signal is indicative of a distance between the tip of the dispenser and the substrate.

Abstract: Electrically resistive devices, such as voltage dividers, and methods of making the same are disclosed. An illustrative voltage divider may include a substrate having an axis, an electrically resistive path applied to the substrate, and at least one terminal positioned around the substrate and in contact with the electrically resistive path. The electrically resistive path may include a primary resistor and a secondary resistor, with the primary resistor having a higher electrical resistance than the secondary resistor. An adjustable displacement of the at least one terminal along the axis of the substrate may allow adjustment of at least one electrical resistance associated with the at least one terminal. An adjustable tightness of the at least one terminal around the substrate may allow adjustment of the at least one electrical resistance associated with the at least one terminal.

Abstract: According to embodiments of the present invention, methods, systems and computer readable media are provided, in a cognitive data processing system, for implementing a predictive analytics system that utilizes entity and non-entity information. A collection of content is processed to extract defined entities pertaining to one or more domains. Semantic relationships are determined between objects within the collection of content, wherein the objects include undefined entities. The defined entities and objects are resolved based on entity definitions and the semantic relationships to determine defined entities and undefined entities for a resulting data set. The resulting data set is processed to identify one or more relationships between a defined entity and an undefined entity.

Abstract: Disclosed herein are compositions and methods employing AMPA Receptor (AMPR) antagonist compounds to treat AMPAR positive cancers in mammalian subjects. In certain detailed embodiments the AMPAR antagonist is a Perampanel compound, effective to mediate potent oncolytic effects to prevent or reduce the severity or recurrence of a variety of cancer forms, including central nervous system (CNS) cancers.

Abstract: According to embodiments of the present invention, methods, systems and computer readable media are provided, in a cognitive data processing system, for implementing a predictive analytics system that utilizes entity and non-entity information. A collection of content is processed to extract defined entities pertaining to one or more domains. Semantic relationships are determined between objects within the collection of content, wherein the objects include undefined entities. The defined entities and objects are resolved based on entity definitions and the semantic relationships to determine defined entities and undefined entities for a resulting data set. The resulting data set is processed to identify one or more relationships between a defined entity and an undefined entity.

Abstract: Provided herein are formulations and methods of use of 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide or a stereoisomer or mixture of stereoisomers, pharmaceutically acceptable salt, tautomer, prodrug, solvate, hydrate, co-crystal, clathrate, or polymorph thereof.