Patents by Inventor Daniel Prows

Daniel Prows has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Apparatus for aseptic vortex flow concentration
    Patent number: 5968355
    Abstract: An apparatus is provided having a rotor inside a membrane for the aseptic vortex flow concentration of a liquid or semisolid dispersion which has a shed-resistant bearing interface so that unwanted bearing material does not contaminate the substances, e.g., pharmaceutical and biological materials, that are being processed.
    Type: Grant
    Filed: November 23, 1998
    Date of Patent: October 19, 1999
    Assignee: Matrix Pharmaceutical, Inc.
    Inventors: Richard Lee, Daniel Prows, Louis Fries
  • Apparatus for aseptic vortex flow concentration
    Patent number: 5925246
    Abstract: An apparatus is provided having a rotor inside a membrane for the aseptic vortex flow concentration of a liquid or semisolid dispersion which has a shed-resistant bearing interface so that unwanted bearing material does not contaminate the substances, e.g., pharmaceutical and biological materials, that are being processed.
    Type: Grant
    Filed: October 31, 1996
    Date of Patent: July 20, 1999
    Assignee: Matrix Pharmaceutical, Inc.
    Inventors: Richard Lee, Daniel Prows, Louis Fries
  • Aseptic collagen concentration process
    Patent number: 5874006
    Abstract: A process for the aseptic concentration of collagen from about 0.25% (w/w) suspensions to gels of 15% using vortex flow filtration with a variety of membrane types--ultrafiltration and microfiltration and polymeric and stainless steel is provided. The resulting gels are suitable for use in medical products and/or pharmaceutical formulations. This process achieves high degree of concentration in a closed system and at high flux with minimal trans-membrane pressure drop.
    Type: Grant
    Filed: October 31, 1996
    Date of Patent: February 23, 1999
    Assignee: Matrix Pharmaceutical, Inc.
    Inventors: Richard Lee, Daniel Prows, Louis Fries
  • Gamma irradiation of collagen/mineral mixtures
    Patent number: 5123925
    Abstract: The present invention is a method for treating bony defects. The method involves contacting the bony defect with a formable composition and allowing the formable composition to solidify. The formable composition is comprised of 2-40% of reconstituted fibrillar atelopeptide collagen and 60-98% calcium phosphate mineral by weight exclusive of moisture. After the formable composition is placed in intimate contact with the bony defect, it is allowed to solidify until it acquires an additional characteristic selected from the group consisting of a compressive modulus of at 10 N/cm.sup.2 or a tensile strength of at least 1 N/cm.sup.2. The method can be used to repair a variety of bony defects such as bone non-union, fresh fractures, periodontal bony pockets, tooth extraction sockets and jaw cysts. Further, the composition can be used to augment an alveolar ridge.
    Type: Grant
    Filed: January 29, 1991
    Date of Patent: June 23, 1992
    Assignee: Collagen Corporation
    Inventors: Thomas L. Smestad, Daniel Prows, George H. Chu, Diana M. Hendericks, Debera Brown
  • Gamma irradiation of collagen/mineral mixtures
    Patent number: 4865602
    Abstract: A process for sterilization of collagen/mineral compositions using .gamma. radiation is conducted under conditions which produce a product of desired handling and biocompatibility properties.
    Type: Grant
    Filed: November 6, 1986
    Date of Patent: September 12, 1989
    Assignee: Collagen Corporation
    Inventors: Thomas L. Smestad, Daniel Prows, George H. Chu, Diana M. Hendricks