Abstract: Compounds of formula (A) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6:

Abstract: Compounds of formula (I) are provided which are useful in the treatment of diseases or conditions modulated at least in part by CCR6:

Abstract: A photoelectric sensor system includes a photoelectric sensor and a retroreflector that is positioned to reflect light emitted by the photoelectric sensor. The photoelectric sensor includes a polarized light source that emits p-polarized light. The photoelectric sensor further includes a Brewster polarizer that is oriented at a Brewster's angle to further polarize the emitted light. The emitted light beam emitted by the photoelectric sensor is reflected off the retroreflector and polarized ninety degrees by the retroreflector to have s-polarization. The reflected light beam is reflected off the Brewster polarizer to a laterally offset light detector.

Abstract: This focus sensor is readily usable in a system using pupil obscuration to measure the state of focus of a light beam. A scattering volumetric filter modifies a three-dimensional wavefront so that focus can be detected by a two-dimensional detector for conversion to a one-dimensional signal having values of plus, zero and minus. This diffusing filter comprises sub wavelength particles having a high index of refraction suspended in an adhesive to produce a solid diffuser. This focus sensor enables a well-behaved focus curve having a constant slope near best focus, while maintaining a slope that is either constant or monotonic at a minimal rate over an extended distance to support a long capture-range over which a focus-controlling servo-mechanism can acquire and maintain focus in the presence of corrupting target surface topography or optical defects.

Abstract: An autofocus system adaptable for use in microscopes or other optical systems incorporates an auxiliary photodetector that measures light only from a reference light source. An outgoing reference beam, incident upon a target to be inspected, is reflected to become an incoming reference beam incident on a photodetector. The photodetector generates a focus error signal proportional to the displacement of the target from the ideal focal point. The auxiliary photodetector generates a correction signal proportional to the output of the reference light source. The correction signal is used to compensate the focus error signal for stray light generated by the reference light source. The compensated focus error signal may be used to drive a servomechanism to displace either the target or the microscope objective lens to bring the target into focus. The correction signal may also be used to compensate the reference light source gain to control the reference light source output.

Abstract: An autofocus system adaptable for use in microscopes or other optical systems incorporates an auxiliary photodetector that measures light only from a reference light source. An outgoing reference beam, incident upon a target to be inspected, is reflected to become an incoming reference beam incident on a photodetector. The photodetector generates a focus error signal proportional to the displacement of the target from the ideal focal point. The auxiliary photodetector generates a correction signal proportional to the output of the reference light source. The correction signal is used to compensate the focus error signal for stray light generated by the reference light source. The compensated focus error signal may be used to drive a servomechanism to displace either the target or the microscope objective lens to bring the target into focus. The correction signal may also be used to compensate the reference light source gain to control the reference light source output.

Abstract: Substituted amide and urea derivatives useful as inhibitors of Rho kinase are described, which inhibitors can be useful in the treatment of various disorders such as cardiovascular diseases, cancer, neurological diseases, renal diseases, bronchial asthma, erectile dysfunction and glaucoma.

Abstract: Substituted amide and urea derivatives useful as inhibitors of Rho kinase are described, which inhibitors can be useful in the treatment of various disorders such as cardiovascular diseases, cancer, neurological diseases, renal diseases, bronchial asthma, erectile dysfunction and glaucoma.

Abstract: A focus sensing system adaptable for use in microscopes or other optical systems incorporates a selective beam block. An outgoing reference beam, incident upon a target to be inspected, is reflected to become an incoming reference beam. A beam block inserted within the optical system selectively rejects unwanted reflections from surfaces other than the target allowing the desired incoming reference beam to be photodetected without interference from reflections off of surfaces that are not of interest. The photodetector generates an electronic signal corresponding to the displacement of the target from the ideal focal point. The electrical signal may be used to drive a servomechanism to displace either the target or the microscope objective lens to bring the target into focus.

Abstract: A distance measuring device capable of being used in microscopes or other optical systems. Embodiments of the invention employ one or more scanning mirrors to scan a reference beam over a target to be inspected. The reference beam is returned and detected by a photodetector. The reference beam may be created by using a knife-edge element which allows the outgoing reference beam and incoming reference beam to follow the same path so that the apparent motion of the spot on the target surface is not detected by the photodetector. The photodetector generates an electronic signal corresponding to the displacement of the target away from the ideal focal point. The electrical signal may be used to drive a servomechanism to displace either the target or the microscope objective lens to bring the target in focus.

Abstract: An X-ray generating apparatus comprises a semiconductor structure, an emitter formed on the semiconductor structure, with the emitter to emit electrons. The apparatus further comprises an element to generate X-rays in response to impact by the electrons on the element.

Abstract: A storage device including many field emitters in close proximity to a storage medium, and a micromover, all in a partial vacuum. Each field emitter can generate an electron beam current. The storage medium has many storage areas on it, with each field emitter responsible for a number of storage areas. Also, each storage area can be in a number of different states to represent the information stored in that area. In storing information to the storage device, the power density of an electron beam current is increased to change the state of the storage area bombarded by the electron beam current. In reading information from the device, the power density of the electron beam current is reduced to generate a signal current from the storage area bombarded by the electron beam current. During reading, the power density is selected to be low enough so that no writing occurs. The magnitude of the signal current depends on the state of the storage area.

Abstract: A data storage device is provided, such data storage device including a storage medium having a data storage location, and at least one emitter adapted to emit an electron beam generally aligned with the data storage location. The data storage device also includes a beam deflector including plural steering electrodes configured to selectively adjust positional alignment of the electron beam relative the data storage location.

Abstract: A focus-detecting emitter for a data storage device is provided, such focus-detecting emitter including a first emission zone configured to selectively produce a first electron beam portion, and a second emission zone configured to selectively produce a second electron beam portion. The first electron beam portion generates a first spot on a storage medium and the second electron beam portion generates a second spot on the storage medium such that a position of at least one of the first spot and the second spot is indicative of a focus state of at least one of the first electron beam portion and the second electron beam portion.

Abstract: Embodiments of emitter clusters for a data storage device are provided, each such emitter cluster including a plurality of electron sources. Each electron source is configured to emit an electron beam to form a collective spot on a storage medium.

Abstract: A swallowable data recorder medical device includes a capsule including a sensing module for sensing a biologic condition within a body. A recording module is provided including an atomic resolution storage device. The recording module is electrically coupled to the sensing module for recording data representative of the sensed biologic condition in the atomic resolution storage device. A power supply is coupled to the recording module.

Abstract: Compounds of Formula (I) 1

Abstract: A storage device including many field emitters in close proximity to a storage medium, and a micromover, all in a partial vacuum. Each field emitter can generate an electron beam current. The storage medium has many storage areas on it, with each field emitter responsible for a number of storage areas. Also, each storage area can be in a number of different states to represent the information stored in that area. In storing information to the storage device, the power density of an electron beam current is increased to change the state of the storage area bombarded by the electron beam current. In reading information from the device, the power density of the electron beam current is reduced to generate a signal current from the storage area bombarded by the electron beam current. During reading, the power density is selected to be low enough so that no writing occurs. The magnitude of the signal current depends on the state of the storage area.

Abstract: The present invention provides a swallowable data recorder medical device. The swallowable data recorder medical device includes a capsule including a sensing module for sensing a biologic condition within a body. A recording module is provided including an atomic resolution storage device. The recording module is electrically coupled to the sensing module for recording data representative of the sensed biologic condition in the atomic resolution storage device. A power supply is coupled to the recording module.

Abstract: The present invention provides a swallowable data recorder medical device. The swallowable data recorder medical device includes a capsule including a sensing module for sensing a biologic condition within a body. A recording module is provided including an atomic resolution storage device. The recording module is electrically coupled to the sensing module for recording data representative of the sensed biologic condition in the atomic resolution storage device. A power supply is coupled to the recording module.