Abstract: According to the invention, a piston fit filter/dispenser vial and method of using same is provided. The vial comprises a conventional filter, for example a piston fit serum filter closing the lower end of the vial and a closure having a pressure source fitting closing off the upper end of the vial. The vial also includes a transfer tube having a first end inside the vial adjacent to the filter and a second end outside vial. Filtrate, for example filtered blood serum, within the vial may be transferred in predetermined aliquots to one or more awaiting sample containers from the vial by applying a predetermined volume of air from a pressure source via the pressure source fitting whereby displaced serum is forced up the transfer tube and out of the vial.