Abstract: A quick-release fire hose clamp for securing a fire hose in place on a fire-fighter's shoulder includes a strap attachment assembly which is releasably fastenable to a backpack strap disposed over the fire-fighter's shoulder. The clamp includes a clamp mechanism that extends upwardly from the strap attachment assembly and has a semi-cylindrically shaped lower hose support body, and a confronting semi-cylindrically shaped upper clamp shell that is pivotable upwardly to enable a length of hose to be laid on the lower hose support body, pivotable downwardly to exert a compressive clamping force on the hose, and pivotable upwardly to release the hose. The clamp mechanism includes a pivotable clasp lever that has a cammed lower surface for exerting a compressive force on the upper surface of the upper clamp shell, the clasp lever being threadingly movable up and down to accommodate larger and smaller hoses, respectively.