Patents by Inventor Daniel Rajadavid Premkumar

Daniel Rajadavid Premkumar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein-Protein Interaction Biosensors and Methods of Use Thereof
    Publication number: 20100112602
    Abstract: The invention provides methods and reagents for identifying an agent, such as by screening a library of agents, that modulates the interaction of two or more polypeptides, the method comprising: introducing into a cell at least a first polypeptide, each comprising a binding domain, wherein the first polypeptide comprises a localization domain of the second polypeptide; and detecting the cellular location of the first polypeptide, the second polypeptide or a combination thereof, wherein a change in the cellular location of the first polypeptide, the second polypeptide or a combination thereof indicates that the agent modulates the interaction of the two or more polypeptides. The invention also provides methods and reagents for identifying the binding domains of one or more polypeptides.
    Type: Application
    Filed: November 9, 2007
    Publication date: May 6, 2010
    Inventors: Lansing D. Taylor, Kenneth A. Giuliano, Daniel Rajadavid Premkumar
  • Fusion proteins and assays for molecular binding
    Patent number: 7244614
    Abstract: The present invention provides novel recombinant fusion proteins for detecting binding of a molecule of interest containing a detection domain, a first and optionally a second localization domain, and a binding domain. The invention also provides recombinant nucleic acid molecules and recombinant expression vectors encoding these novel fusion proteins, genetically engineered host cells containing these expression vectors, and kits for the use of these fusion proteins, nucleic acid molecules, expression vectors, and host cells. Additionally, the present invention provides methods for identifying compounds that alter the binding of a molecule of interest in a cell.
    Type: Grant
    Filed: August 1, 2002
    Date of Patent: July 17, 2007
    Assignee: Cellomics, Inc.
    Inventors: Gary Bright, Daniel Rajadavid Premkumar, Yih-Tai Chen
  • Novel fusion proteins and assays for molecular binding
    Publication number: 20030104479
    Abstract: The present invention provides novel recombinant fusion proteins for detecting binding of a molecule of interest containing a detection domain, a first and optionally a second localization domain, and a binding domain. The invention also provides recombinant nucleic acid molecules and recombinant expression vectors encoding these novel fusion proteins, genetically engineered host cells containing these expression vectors, and kits for the use of these fusion proteins, nucleic acid molecules, expression vectors, and host cells. Additionally, the present invention provides methods for identifying compounds that alter the binding of a molecule of interest in a cell.
    Type: Application
    Filed: August 1, 2002
    Publication date: June 5, 2003
    Applicant: Cellomics, Inc.
    Inventors: Gary Bright, Daniel Rajadavid Premkumar, Yih-Tai Chen