Abstract: An oscillator and method for maintaining a phase lock is provided. The oscillator may include an oscillator input port for receiving a reference signal, an oscillator output port for outputting an oscillator output, an unlocked oscillator oscillating in an unlocked state and outputting at a resonance frequency configured to drift in response to changes in an operating environment, and a phase locked loop (PLL) including a mixer having an output port configured to output the unlocked oscillator output mixed with a local oscillator output, the mixer output port in communication with a phase frequency detector and the oscillator output port, and the phase frequency detector generating a control signal based on a detected phase difference between the reference signal and the mixer output wherein the control signal adjusts the local oscillator output to compensate for the resonance frequency drift of the unlocked oscillator when mixed with the unlocked oscillator output.

Abstract: A method for determining an edge profile of a custom decorative article to be installed in an installation area is disclosed, the installation area having a perimeter having a plurality of corners. A computing device receives data indicative of a plurality of coordinates corresponding to the plurality of corners of the perimeter of the installation area. Based on at least first, second, and third coordinates respectively corresponding to first, second, and third corners of the plurality of corners of the perimeter of the installation area, the computing device determines dimensional and/or geometric characteristics of a pair of opposed portions of the edge profile that, in an installed position, are configured to meet to form a corner of the custom decorative article when installed at the second corner of the perimeter of the installation area.

Abstract: A method for determining an edge profile of a custom decorative article to be installed in an installation area is disclosed, the installation area having a perimeter having a plurality of corners. A computing device receives data indicative of a plurality of coordinates corresponding to the plurality of corners of the perimeter of the installation area. Based on at least first, second, and third coordinates respectively corresponding to first, second, and third corners of the plurality of corners of the perimeter of the installation area, the computing device determines dimensional and/or geometric characteristics of a pair of opposed portions of the edge profile that, in an installed position, are configured to meet to form a corner of the custom decorative article when installed at the second corner of the perimeter of the installation area.

Abstract: A vehicle thermal management system includes a vehicle heat pump system, a battery system coolant loop, a drive train coolant loop, and control electronics. The vehicle heat pump system includes a compressor, a cabin condenser, a cabin evaporator, a cabin blower, and a chiller. The battery system coolant loop is in thermal communication with a battery system and with the chiller and selectively in thermal communication with the drive train coolant loop. The control electronics control the components of the vehicle thermal management system to heat the cabin, cool the cabin, heat the battery system, cool the battery system, and cool the drive train. The control electronics may control the compressor to operate in an efficient mode or a lossy mode in which the compressor generates heat. The control electronics may also control the components of the vehicle thermal management system to precondition the battery.

Abstract: A group definition is received via a network interface. Communications are transmitted to destinations, the communications comprising an invitation to associate with the a content sharing group. Authentication data associated with users that accept the invention is encrypted. The accepting users are associated with the content sharing group. A content gallery definition is received. A communication is received that the content gallery is to be shared with the content sharing group. The content gallery is caused to be instantiated on devices of users associated with the group. A content request for the content sharing group is received and the content request is transmitted accordingly to users associated with the group. A content item is received in response the request and the content item is transmitted to user devices associated with the group and enabled to appear in instantiations of the content gallery on the user devices.

Abstract: An apparatus is disclosed comprising a first device for generating aerosol, smoke or vapour from one or more regions of a target, an inlet conduit to an ion analyser or mass spectrometer, the inlet conduit having an inlet through which the aerosol, smoke or vapour passes, and a Venturi pump arrangement arranged and adapted to direct the aerosol, smoke or vapour towards the inlet.

Abstract: A method includes receiving, by a memory management unit (MMU) comprising a translation lookaside buffer (TLB) and a configuration register, a request from a processor core to directly modify an entry in the TLB. The method also includes, responsive to the configuration register having a first value, operating the MMU in a software-managed mode by modifying the entry in the TLB according to the request. The method further includes, responsive to the configuration register having a second value, operating the MMU in a hardware-managed mode by denying the request.

Abstract: Techniques including a memory controller with a set of memory channel queues, wherein memory channel queues of the set of memory channel queues correspond to memory channels to access a set of memory modules, a first arbitration module, and a second arbitration module. The memory controller is configured to receive a first memory request from the peripheral and place one or more portions of the first memory request in the memory channel queues of the set of memory channel queues. The first arbitration module is configured to determine an arbitration algorithm, select a first memory channel queue based on the arbitration algorithm, present the one or more portions of the first memory request in the selected first memory channel queue to the second arbitration module, and output the presented one or more portions of the first memory request based on a selection by the second arbitration module.

Abstract: Various implementations include adaptive masking of environmental sound. Particular implementations are configured to adjust a masking sound based on one or more detected environmental sound sources. An example method includes: measuring environmental sound proximate to an audio device, outputting a masking sound at the audio device, and adjusting at least one of: a volume of the masking sound, a spectrum of the masking sound, or content of the masking sound based on the measured environmental sound.

Abstract: Methods and systems of enabling a non-interfering mode in a telematics device are provided. The method may be used to prevent interference between a telematics device and a diagnostic tool connected to the same vehicle communications bus. When a diagnostic tool is detected, the telematics device enables a non-interfering mode. Advantageously, the operation of diagnostic tools such as emissions testing diagnostic tools, is not disrupted.

Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating cystic fibrosis, e.g., in subjects having a mutation resulting in F508del, are described.

Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating phenylketonuria (PKU) are described.

Abstract: Systems and methods are provided for dynamically modeling and depicting overall emissions of the aviation industry and changes thereto when taking into account, for example, traffic growth and introduction of sustainability strategies, such as new and/or improved technologies, an increase in operational efficiency, and carbon offsets. Using the dynamic tool described herein, users can define scenarios on how to reduce emissions through the introduction of different sustainability strategies, both statically and over time, analyze the impact of those strategies on emissions, and understand the dependencies between select strategies.

Abstract: The disclosure provides, e.g., compositions, systems, and methods for targeting, editing, modifying, or manipulating a host cell's genome at one or more locations in a DNA sequence in a cell, tissue, or subject. Gene modifying systems for treating alpha-1 antitrypsin deficiency (AATD) are described.

Abstract: Instrument control and data acquisition in advanced analytic systems that utilize optical pulses for sample analysis are described. Clocking signals for data acquisition, data processing, communication, and/or other data handling functionalities can be derived from an on-board pulsed optical source, such as a passively mode-locked laser. The derived clocking signals can operate in combination with one or more clocking signals from a stable oscillator, so that instrument operation and data handling can tolerate interruptions in operation of the pulsed optical source.

Abstract: An internal combustion engine system is described herein. The internal combustion engine system uses one or more fuels that may be hydrophilic. The system uses a water measuring sensor to determine the concentration of water in the hydrophilic fuel. To meet power demands, the system uses the measured water concentration to modify data stored in a fuel map. The fuel map provides a controller the pump speeds and mixing ratio of the fuels for a given power level. The system receives that data and modifies it based on the measured concentration of water.

Abstract: A fuel delivery system for an internal combustion engine system is described herein. The fuel delivery system uses one or more bidirectional purge components to provide for bidirectional purging of a fuel from at least a portion of the fuel delivery system. The bidirectional purge components provide for a fuel delivered using the fuel delivery system to be purged into the directional purge component in more than one fluid flow direction. When a differential pressure is applied across the bidirectional purge component, the fuel is purged into an inlet and an outlet of the bidirectional purge component, leaving the component through a purge outlet and into a tank. The differential pressure can be generated using a pressured fluid such as nitrogen or a pump downstream of the purge outlet.

Abstract: An eye measurement system includes an optical system. The eye measurement system is disposed in a housing which includes an aperture for providing light to and from the optical system and a subject's eye while the subject is separated and spaced apart from the housing, and the eye is not maintained in a fixed positional relationship with respect to the housing. An optical system movement arrangement moves the optical system. An automatic eye tracking arrangement ascertains a current positional relationship of the eye with respect to the optical system without human assistance, and in response thereto controls the optical system movement arrangement to move the optical system into a predetermined positional relationship with respect to the eye, for measurement of the eye, without human assistance. The eye measurement system can make objective, and/or subjective, refraction measurements of the eye.

Abstract: Provided is a method for designing a patient-specific surgical device for performing knee surgery, which includes determining a first alignment axis and/or a second alignment axis from a knee joint in extension and/or flexion respectively and subsequently designing said surgical device based on the first and/or second alignment axes. Also provided is a method of manufacturing a patient-specific surgical device designed by the aforementioned method. A patient-specific surgical device designed and/or manufactured by the above methods and a method of performing knee surgery with said patient-specific surgical device is further provided.

Abstract: Systems for enabling or disabling a non-interfering mode in a telematics device are provided. The system is comprised of a telematics server and a telematics device. The telematics server determines that a telematics device coupled to an asset communications bus of an asset may enter or exit a non-interfering mode.