Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: A system and method of monitoring sobriety using a hand-held breath testing device that, on receipt of a user's breath, generates a breath test signal comprising substance content data and user identification data, and wirelessly transmits the breath test signal to a breath test signal receiving station.

Abstract: A method for assessing imagination includes providing, to each of a plurality of assessment subjects, at a first time, a first assessment prompt. The method includes receiving, from each of the assessment subjects, a first response to the first assessment prompt. The method includes safeguarding each of the received first responses. The method includes providing, to each of the assessment subjects, at a second time subsequent to the first time, a second assessment prompt. The method includes receiving, from each of the assessment subjects, a second response to the second assessment prompt. The method includes safeguarding each of the second responses. The method includes receiving, from each of the assessment subjects, a self-evaluation of the first response and the second response. The method includes analyzing the received responses and self-evaluations. The method includes generating a recommendation for a modification to a resource available to the plurality of assessment subjects.

Abstract: Systems, methods and devices are disclosed for monitoring sobriety of a first user by a second user which can be discrete, wirelessly linked via a communications network and can provide various forms of alerts to the first and second users.

Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: A method of manufacturing a variable focus fluid lens assembly which includes mounting a membrane assembly within a recess formed in a lens housing said assembly including a distensible transparent membrane supported round its periphery by a supporting member and a flexible tubular wall having first and second opposite ends one of said ends being joined to the supporting member to form a cavity within the wall that is closed at the one end by the membrane; filling the cavity with a transparent fluid and fitting a transparent cover plate to the housing across the other end of the wall. The other end being joined sealingly to the cover plate or to the housing thereby to seal the cavity to form a compressible fluid-filled envelope. The cover plate may include a fixed lens selected from a stock of lenses having the same shape for fitting to the lens assembly, but different other optical properties, such for example as different base curves and/or decentration distances.

Abstract: The disclosure provides gene fusions, gene variants, and novel associations with disease states, as well as kits, probes, and methods of using the same.

Abstract: The disclosure provides compositions, kits, and methods for detecting a plurality of genes and associated variants in a sample from a subject with cancer. The compositions, kits, and methods include a set of oligonucleotides, typically primers and/or probes that can hybridize to identify a gene variant. The methods disclosed herein provide for a mutation status of a tumor to be determined and subsequently associated with a report comprising an actionable treatment recommendation.

Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: The disclosure provides gene fusion variants and novel associations with disease states, as well as kits, probes, and methods of using the same.

Abstract: A system and method of monitoring sobriety using a hand-held breath testing device that, on receipt of a user's breath, generates a breath test signal comprising substance content data and user identification data, and wirelessly transmits the breath test signal to a breath test signal receiving station.

Abstract: The disclosure provides gene fusions, gene variants, and novel associations with disease states, as well as kits, probes, and methods of using the same.

Abstract: A method for sorting particles in a fluid. The method involves generating an optical landscape using an acousto-optic device. Preferably, the optical landscape is arranged to sort particles based on size or refractive index or shape.

Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: Recurrent gene fusions of androgen regulated genes and ETS family member genes in prostate cancer are described. Compositions and methods having utility in prostate cancer diagnosis, research, and therapy are also provided.

Abstract: An antenna for communicating with mobile devices in a land-based cellular communication system via an antenna beam having a width, azimuth angle and downtilt angle. The antenna includes: a two dimensional array of radiating elements (31-34); and a feed network (35-39) from a feed line to the radiating elements. The feed network includes: downtilt phase shifting means (35,36) for varying the phase of signals supplied to or received from the radiating elements so as to vary the downtilt angle of the antenna beam; azimuth phase shifting (38,39) means for varying the phase of signals supplied to or received from the radiating elements so as to vary the azimuth angle of the antenna beam; and beam width adjustment means (37) for varying the power or phase of signals supplied to or received from the radiating elements so as to vary the width of the antenna beam.