Patents by Inventor Daniel Roa

Daniel Roa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PRMT5 INHIBITORS AND USES THEREOF
    Publication number: 20250388585
    Abstract: The present disclosure relates generally to compounds that inhibit PRMT5. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting PRMT5. The disclosure further relates to the use of the compounds for the treatment of a disease or condition associated with chromosome 9p21 deletion, MTAP null, or any other MTAP deficiency. The disclosure further relates to the use of the compounds for the treatment of cancers.
    Type: Application
    Filed: June 4, 2025
    Publication date: December 25, 2025
    Inventors: Megan K. Armstrong, Elbert Chin, Chienhung Chou, Laurent P. Debien, Yifan Deng, Joshua D. Farr, Pancham Lal Gupta, Chao-I Hung, Benjamin J. June, Prasenjit K. Mukherjee, Shaina V. Nguyen, Gregory T. Notte, Daniel Roa, Adam J. Schrier, Katie A. Spence, Zheng-Yu Yang
  • PRMT5 inhibitors and uses thereof
    Patent number: 12448388
    Abstract: The present disclosure relates generally to compounds that inhibit PRMT5. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting PRMT5. The disclosure further relates to the use of the compounds for the treatment of a disease or condition associated with chromosome 9p21 deletion, MTAP null, or any other MTAP deficiency. The disclosure further relates to the use of the compounds for the treatment of cancers.
    Type: Grant
    Filed: May 14, 2024
    Date of Patent: October 21, 2025
    Assignee: Gilead Sciences, Inc.
    Inventors: Megan K. Armstrong, Elbert Chin, Chienhung Chou, Laurent P. Debien, Yifan Deng, Joshua D. Farr, Pancham Lal Gupta, Chao-I Hung, Benjamin J. June, Prasenjit K. Mukherjee, Shaina V. Nguyen, Gregory T. Notte, Daniel Roa, Adam J. Schrier, Katie A. Spence, Zheng-Yu Yang
  • PRMT5 INHIBITORS AND USES THEREOF
    Publication number: 20250154172
    Abstract: The present disclosure relates generally to compounds that inhibit PRMT5. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting PRMT5. The disclosure further relates to the use of the compounds for the treatment of a disease or condition associated with chromosome 9p21 deletion or MTAP null. The disclosure further relates to the use of the compounds for the treatment of cancers.
    Type: Application
    Filed: October 30, 2024
    Publication date: May 15, 2025
    Inventors: Megan K. Armstrong, Elbert Chin, Chienhung Chou, Laurent P. Debien, Yifan Deng, Joshua D. Farr, Chao-I Hung, Benjamin J. June, Shaina V. Nguyen, Daniel Roa, Katie A. Spence, Zheng-Yu Yang
  • PRMT5 INHIBITORS AND USES THEREOF
    Publication number: 20240376110
    Abstract: The present disclosure relates generally to compounds that inhibit PRMT5. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting PRMT5. The disclosure further relates to the use of the compounds for the treatment of a disease or condition associated with chromosome 9p21 deletion, MTAP null, or any other MTAP deficiency. The disclosure further relates to the use of the compounds for the treatment of cancers.
    Type: Application
    Filed: May 14, 2024
    Publication date: November 14, 2024
    Inventors: Megan K. Armstrong, Elbert Chin, Chienhung Chou, Laurent P. Debien, Yifan Deng, Joshua D. Farr, Pancham Lal Gupta, Chao-I Hung, Benjamin J. June, Prasenjit K. Mukherjee, Shaina V. Nguyen, Gregory T. Notte, Daniel Roa, Adam J. Schrier, Katie A. Spence, Zheng-Yu Yang
  • PRMT5 INHIBITORS AND USES THEREOF
    Publication number: 20240254118
    Abstract: The present disclosure relates generally to compounds that inhibit PRMT5. The disclosure further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through inhibiting PRMT5. The disclosure further relates to the use of the compounds for the treatment of a disease or condition associated with chromosome 9p21 deletion or MTAP null. The disclosure further relates to the use of the compounds for the treatment of cancers.
    Type: Application
    Filed: December 20, 2023
    Publication date: August 1, 2024
    Inventors: Megan K. Armstrong, Elbert Chin, Chienhung Chou, Laurent P. Debien, Joshua D. Farr, Pancham Lal Gupta, Chao-I Hung, Michael L. Mitchell, Prasenjit K. Mukherjee, Shaina V. Nguyen, Gregory T. Notte, Daniel Roa, Adam J. Schrier, Zheng-Yu Yang