Patents by Inventor Daniel Roxbury

Daniel Roxbury has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Wearable optical microfibrous material with encapsulated nanosensors for wireless monitoring of chemical analytes
    Patent number: 12446804
    Abstract: An optical core-shell microfibrous textile incorporates single-walled carbon nanotubes (SWCNTs) for the real-time optical monitoring of hydrogen peroxide concentrations and other biochemicals in in vitro wounds. The environmentally sensitive and non-photo-bleachable fluorescence of SWCNTs enable continuous analyte monitoring without a decay in signal over time. The microfibrous textiles spatially resolve chemical indicator concentrations using a camera and are integrated into commercial wound bandages without significant degradation in their optical properties.
    Type: Grant
    Filed: February 1, 2022
    Date of Patent: October 21, 2025
    Assignee: University of Rhode Island Board of Trustees
    Inventors: Daniel Roxbury, Mohammad Moein Safaee, Mitchell Gravely
  • COMPOSITION AND METHOD FOR MONITORING LIPID
    Publication number: 20220276171
    Abstract: A method of detecting a condition in a subject comprises the steps of contacting cells of the subject with single-walled carbon nanotubes (SWCNTs), monitoring photoluminescence emitted by SWCNTs internalized into the cells and generating an SW-CNT emission profile, comparing the SWCNT emission profile to a control emission profile for the SWCNTs to produce a result, and determining a likelihood of having the condition in the subject based on the result from the comparing step. Also disclosed is a method for screening agents capable of changing endocytic environment using SWCNTs.
    Type: Application
    Filed: October 8, 2021
    Publication date: September 1, 2022
    Inventors: Prakrit JENA, Daniel A. HELLER, Daniel ROXBURY
  • WEARABLE OPTICAL MICROFIBROUS MATERIAL WITH ENCAPSULATED NANOSENSORS FOR WIRELESS MONITORING OF CHEMICAL ANALYTES
    Publication number: 20220248983
    Abstract: An optical core-shell microfibrous textile incorporates single-walled carbon nanotubes (SWCNTs) for the real-time optical monitoring of hydrogen peroxide concentrations and other biochemicals in in vitro wounds. The environmentally sensitive and non-photo-bleachable fluorescence of SWCNTs enable continuous analyte monitoring without a decay in signal over time. The microfibrous textiles spatially resolve chemical indicator concentrations using a camera and are integrated into commercial wound bandages without significant degradation in their optical properties.
    Type: Application
    Filed: February 1, 2022
    Publication date: August 11, 2022
    Applicant: University of Rhode Island Board of Trustees
    Inventors: Daniel Roxbury, Mohammad Moein Safaee, Mitchell Gravely
  • COMPOSITION AND METHOD FOR MONITORING LIPID
    Publication number: 20190383744
    Abstract: A method of detecting a condition in a subject comprises the steps of contacting cells of the subject with single-walled carbon nanotubes (SWCNTs), monitoring photoluminescence emitted by SWCNTs internalized into the cells and generating an SWCNT emission profile, comparing the SWCNT emission profile to a control emission profile for the SWCNTs to produce a result, and determining a likelihood of having the condition in the subject based on the result from the comparing step. Also disclosed is a method for screening agents capable of changing endocytic environment using SWCNTs.
    Type: Application
    Filed: August 22, 2019
    Publication date: December 19, 2019
    Inventors: Prakrit JENA, Daniel A. HELLER, Daniel ROXBURY
  • Composition and method for monitoring lipid
    Patent number: 10401295
    Abstract: A method of detecting a condition in a subject comprises the steps of contacting cells of the subject with single-walled carbon nanotubes (SWCNTs), monitoring photoluminescence emitted by SWCNTs internalized into the cells and generating an SWCNT emission profile, comparing the SWCNT emission profile to a control emission profile for the SWCNTs to produce a result, and determining a likelihood of having the condition in the subject based on the result from the comparing step. Also disclosed is a method for screening agents capable of changing endocytic environment using SWCNTs.
    Type: Grant
    Filed: May 28, 2015
    Date of Patent: September 3, 2019
    Assignee: Memorial Sloan Kettering Cancer Center
    Inventors: Prakrit Jena, Daniel A. Heller, Daniel Roxbury
  • COMPOSITION AND METHOD FOR MONITORING LIPID
    Publication number: 20170199126
    Abstract: A method of detecting a condition in a subject comprises the steps of contacting cells of the subject with single-walled carbon nanotubes (SWCNTs), monitoring photoluminescence emitted by SWCNTs internalized into the cells and generating an SWCNT emission profile, comparing the SWCNT emission profile to a control emission profile for the SWCNTs to produce a result, and determining a likelihood of having the condition in the subject based on the result from the comparing step. Also disclosed is a method for screening agents capable of changing endocytic environment using SWCNTs.
    Type: Application
    Filed: May 28, 2015
    Publication date: July 13, 2017
    Inventors: Prakrit Jena, Daniel A. Heller, Daniel Roxbury