Abstract: A novel gRNA-ligand binding complex is provided. This complex may be used to bring Type V Cas proteins and additional effectors to DNA for base editing. The design of the systems allows for the production of efficient modular components that provide flexibility when editing DNA.

Abstract: A novel gRNA-ligand binding complex is provided. This complex may be used to bring Type V Cas proteins and additional effectors to DNA for base editing. The design of the systems allows for the production of efficient modular components that provide flexibility when editing DNA.

Abstract: Systems and methods relate to a Self-Organizing Network (SON) that makes changes to operating parameters for the purpose of load balancing, to increase data communication throughput and capacity. A device may determine load balancing ratios and unused throughput for a first frequency band and a second frequency band for a cell site. The device may also determine, based on the load balancing ratios and the unused throughputs, whether a load balancing procedure for the cell site should be performed to increase a traffic throughput at the cell site.

Abstract: A method, a device, and a non-transitory storage medium provide a node placement service. The node placement service may generate geo-bins pertaining to a radio access network device, a sector of the radio access network device, or a sub-sector. The node placement service may generate time values for the geo-bins based on network information associated with end devices and the geo-bins. The node placement service may also generate return on investment values for the geo-bins based on the network information. The node placement service may use the time values, the return on investment values, or both for radio frequency design of a geo-bin.

Abstract: A method for user equipment (UE) based network capability scoring for wireless wide area network management includes receiving parameters associated with a performance of a network, user equipment devices network utilization, and/or user application requirements. The method further includes determining throughput evaluations of data exchanges between UEs and sectors associated with cell sites within the network, and identifying device performance scores based on the throughput evaluations. The device performance scores may be adjusted based on at least one independent metric. The method may evaluate sectors based on the identified device performance scores.

Abstract: Systems and methods relate to a Self-Organizing Network (SON) that makes changes to operating parameters for the purpose of load balancing, to increase data communication throughput and capacity. A device may determine load balancing ratios and unused throughput for a first frequency band and a second frequency band for a cell site. The device may also determine, based on the load balancing ratios and the unused throughputs, whether a load balancing procedure for the cell site should be performed to increase a traffic throughput at the cell site.

Abstract: Systems and methods relate to a Self-Organizing Network (SON) that makes changes to operating parameters for the purpose of load balancing, to increase data communication throughput and capacity. A device may determine load balancing ratios and unused throughput for a first frequency band and a second frequency band for a cell site. The device may also determine, based on the load balancing ratios and the unused throughputs, whether a load balancing procedure for the cell site should be performed to increase a traffic throughput at the cell site.

Abstract: A method, a device, and a non-transitory storage medium provide a node placement service. The node placement service may generate geo-bins pertaining to a radio access network device, a sector of the radio access network device, or a sub-sector. The node placement service may generate time values for the geo-bins based on network information associated with end devices and the geo-bins. The node placement service may also generate return on investment values for the geo-bins based on the network information. The node placement service may use the time values, the return on investment values, or both for radio frequency design of a geo-bin.

Abstract: A method for user equipment (UE) based network capability scoring for wireless wide area network management includes receiving parameters associated with a performance of a network, user equipment devices network utilization, and/or user application requirements. The method further includes determining throughput evaluations of data exchanges between UEs and sectors associated with cell sites within the network, and identifying device performance scores based on the throughput evaluations. The device performance scores may be adjusted based on at least one independent metric. The method may evaluate sectors based on the identified device performance scores.

Abstract: A method, a device, and a non-transitory storage medium provide a node placement service. The node placement service may generate geo-bins pertaining to a radio access network device, a sector of the radio access network device, or a sub-sector. The node placement service may generate time values for the geo-bins based on network information associated with end devices and the geo-bins. The node placement service may also generate return on investment values for the geo-bins based on the network information. The node placement service may use the time values, the return on investment values, or both for radio frequency design of a geo-bin.

Abstract: Systems and methods relate to a Self-Organizing Network (SON) that makes changes to operating parameters for the purpose of load balancing, to increase data communication throughput and capacity. A device may determine load balancing ratios and unused throughput for a first frequency band and a second frequency band for a cell site. The device may also determine, based on the load balancing ratios and the unused throughputs, whether a load balancing procedure for the cell site should be performed to increase a traffic throughput at the cell site.

Abstract: A method, a device, and a non-transitory storage medium provide a node placement service. The node placement service may generate geo-bins pertaining to a radio access network device, a sector of the radio access network device, or a sub-sector. The node placement service may generate time values for the geo-bins based on network information associated with end devices and the geo-bins. The node placement service may also generate return on investment values for the geo-bins based on the network information. The node placement service may use the time values, the return on investment values, or both for radio frequency design of a geo-bin.