Patents by Inventor Daniel S. Johnston

Daniel S. Johnston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11961974
    Abstract: A battery cell capable of self-priming with molten metal produced within the battery cell includes a cathode compartment configured to contain a catholyte that releases metal ions, an anode compartment at least partially containing an anode current collector that receives electrons from an external power supply, an ion-selective membrane positioned between the cathode compartment and the anode compartment and configured to selectively transport the metal ions from the cathode compartment to the anode compartment when self-priming the battery cell, and an electron transport structure extending between the anode current collector and the ion-selective membrane within the anode compartment and configured to transport the electrons from the anode current collector to the ion-selective membrane when self-priming the battery cell.
    Type: Grant
    Filed: April 21, 2023
    Date of Patent: April 16, 2024
    Assignee: Enlighten Innovations Inc.
    Inventors: Sai V. Bhavaraju, Daniel S. Taggart, Mykola Makowsky, Joshua D. Johnston, Steven W. Hughes
  • Publication number: 20240102993
    Abstract: A method for optimal selection of cytotoxic agents for organ or region specific therapy that includes extracorporeal filtration of the cytotoxic agent from blood drained from the organ or region being treated and return of the filtered blood to a mammal is disclosed.
    Type: Application
    Filed: November 29, 2023
    Publication date: March 28, 2024
    Applicant: Delcath Systems, Inc.
    Inventors: Eamonn P. Hobbs, Daniel S. Johnston
  • Patent number: 11867686
    Abstract: A method for optimal selection of cytotoxic agents for organ or region specific therapy that includes extracorporeal filtration of the cytotoxic agent from blood drained from the organ or region being treated and return of the filtered blood to a mammal is disclosed.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: January 9, 2024
    Assignee: Delcath Systems, Inc.
    Inventors: Eamonn P. Hobbs, Daniel S. Johnston
  • Publication number: 20230211063
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: March 10, 2023
    Publication date: July 6, 2023
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 11633528
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: December 21, 2021
    Date of Patent: April 25, 2023
    Assignee: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Publication number: 20220111132
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: December 21, 2021
    Publication date: April 14, 2022
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 11241522
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: February 8, 2022
    Assignee: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Publication number: 20200300839
    Abstract: A method for optimal selection of cytotoxic agents for organ or region specific therapy that includes extracorporeal filtration of the cytotoxic agent from blood drained from the organ or region being treated and return of the filtered blood to a mammal is disclosed.
    Type: Application
    Filed: June 4, 2020
    Publication date: September 24, 2020
    Applicant: Delcath Systems, Inc.
    Inventors: Eamonn P. Hobbs, Daniel S. Johnston
  • Publication number: 20200147288
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: January 10, 2020
    Publication date: May 14, 2020
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 10569004
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: February 25, 2020
    Assignee: DELCATH SYSTEMS, INC.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Publication number: 20190290823
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: June 12, 2019
    Publication date: September 26, 2019
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 10369264
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: August 6, 2019
    Assignee: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Publication number: 20190001044
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: September 10, 2018
    Publication date: January 3, 2019
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 10098997
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: October 16, 2018
    Assignee: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Publication number: 20180028740
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Application
    Filed: July 17, 2017
    Publication date: February 1, 2018
    Applicant: Delcath Systems, Inc.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 9707331
    Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.
    Type: Grant
    Filed: November 7, 2012
    Date of Patent: July 18, 2017
    Assignee: DELCATH SYSTEMS, INC.
    Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
  • Patent number: 9541544
    Abstract: A method for optimal selection of cytotoxic agents for organ or region specific therapy that includes extracorporeal filtration of the cytotoxic agent from blood drained from the organ or region being treated and return of the filtered blood to a mammal is disclosed.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: January 10, 2017
    Assignee: Delcath Systems, Inc.
    Inventors: Eamonn P. Hobbs, Daniel S. Johnston
  • Patent number: 5996969
    Abstract: A staple removal tool includes an elongated handle mounting a U-shaped cover member supporting a U-shaped base member formed with a forwardly projecting staple lifter tongue. A crimping arm is pivoted on the base member for movement toward and away from the staple lifter tongue and is actuated by a hand lever located under the handle and pivotally secured at its forward end to the cover member. A spring loaded link member is attached at one end to the hand lever and at the opposite end to the crimping arm, whereby pivoting of the handle lever effects pivotal movement of the crimping arm. A crimping bar is secured to and spaced from the base member to receive the clamping arm between them. The staple lifter tongue engages under the bridge portion of a staple, such as a roofing staple, and leveraging of the handle pulls the staple from its wood anchor.
    Type: Grant
    Filed: April 17, 1998
    Date of Patent: December 7, 1999
    Inventors: Daniel S. Johnston, Michael A. Quesada