Patents by Inventor Daniel S. Johnston
Daniel S. Johnston has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11961974Abstract: A battery cell capable of self-priming with molten metal produced within the battery cell includes a cathode compartment configured to contain a catholyte that releases metal ions, an anode compartment at least partially containing an anode current collector that receives electrons from an external power supply, an ion-selective membrane positioned between the cathode compartment and the anode compartment and configured to selectively transport the metal ions from the cathode compartment to the anode compartment when self-priming the battery cell, and an electron transport structure extending between the anode current collector and the ion-selective membrane within the anode compartment and configured to transport the electrons from the anode current collector to the ion-selective membrane when self-priming the battery cell.Type: GrantFiled: April 21, 2023Date of Patent: April 16, 2024Assignee: Enlighten Innovations Inc.Inventors: Sai V. Bhavaraju, Daniel S. Taggart, Mykola Makowsky, Joshua D. Johnston, Steven W. Hughes
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Publication number: 20240102993Abstract: A method for optimal selection of cytotoxic agents for organ or region specific therapy that includes extracorporeal filtration of the cytotoxic agent from blood drained from the organ or region being treated and return of the filtered blood to a mammal is disclosed.Type: ApplicationFiled: November 29, 2023Publication date: March 28, 2024Applicant: Delcath Systems, Inc.Inventors: Eamonn P. Hobbs, Daniel S. Johnston
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Patent number: 11867686Abstract: A method for optimal selection of cytotoxic agents for organ or region specific therapy that includes extracorporeal filtration of the cytotoxic agent from blood drained from the organ or region being treated and return of the filtered blood to a mammal is disclosed.Type: GrantFiled: June 4, 2020Date of Patent: January 9, 2024Assignee: Delcath Systems, Inc.Inventors: Eamonn P. Hobbs, Daniel S. Johnston
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Publication number: 20230211063Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: March 10, 2023Publication date: July 6, 2023Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 11633528Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: December 21, 2021Date of Patent: April 25, 2023Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20220111132Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: December 21, 2021Publication date: April 14, 2022Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 11241522Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: January 10, 2020Date of Patent: February 8, 2022Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20200300839Abstract: A method for optimal selection of cytotoxic agents for organ or region specific therapy that includes extracorporeal filtration of the cytotoxic agent from blood drained from the organ or region being treated and return of the filtered blood to a mammal is disclosed.Type: ApplicationFiled: June 4, 2020Publication date: September 24, 2020Applicant: Delcath Systems, Inc.Inventors: Eamonn P. Hobbs, Daniel S. Johnston
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Publication number: 20200147288Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: January 10, 2020Publication date: May 14, 2020Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10569004Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: June 12, 2019Date of Patent: February 25, 2020Assignee: DELCATH SYSTEMS, INC.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20190290823Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: June 12, 2019Publication date: September 26, 2019Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10369264Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: September 10, 2018Date of Patent: August 6, 2019Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20190001044Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: September 10, 2018Publication date: January 3, 2019Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 10098997Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: July 17, 2017Date of Patent: October 16, 2018Assignee: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Publication number: 20180028740Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: ApplicationFiled: July 17, 2017Publication date: February 1, 2018Applicant: Delcath Systems, Inc.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 9707331Abstract: A filter apparatus for removing small molecule chemotherapy agents from blood is provided. The filter apparatus comprises a housing with an extraction media comprised of polymer coated carbon cores. Also provided are methods of treating a subject with cancer of an organ or region comprising administering a chemotherapeutic agent to the organ or region, collecting blood laded with chemotherapeutic agent from the isolated organ, filtering the blood laden with chemotherapeutic agent to reduce the chemotherapeutic agent in the blood and returning the blood to the subject.Type: GrantFiled: November 7, 2012Date of Patent: July 18, 2017Assignee: DELCATH SYSTEMS, INC.Inventors: Daniel S. Johnston, Jacques Chammas, William M. Appling, Samantha J. Barton
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Patent number: 9541544Abstract: A method for optimal selection of cytotoxic agents for organ or region specific therapy that includes extracorporeal filtration of the cytotoxic agent from blood drained from the organ or region being treated and return of the filtered blood to a mammal is disclosed.Type: GrantFiled: August 28, 2013Date of Patent: January 10, 2017Assignee: Delcath Systems, Inc.Inventors: Eamonn P. Hobbs, Daniel S. Johnston
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Patent number: 5996969Abstract: A staple removal tool includes an elongated handle mounting a U-shaped cover member supporting a U-shaped base member formed with a forwardly projecting staple lifter tongue. A crimping arm is pivoted on the base member for movement toward and away from the staple lifter tongue and is actuated by a hand lever located under the handle and pivotally secured at its forward end to the cover member. A spring loaded link member is attached at one end to the hand lever and at the opposite end to the crimping arm, whereby pivoting of the handle lever effects pivotal movement of the crimping arm. A crimping bar is secured to and spaced from the base member to receive the clamping arm between them. The staple lifter tongue engages under the bridge portion of a staple, such as a roofing staple, and leveraging of the handle pulls the staple from its wood anchor.Type: GrantFiled: April 17, 1998Date of Patent: December 7, 1999Inventors: Daniel S. Johnston, Michael A. Quesada