Patents by Inventor Daniel S. Pilch
Daniel S. Pilch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210088525Abstract: The invention provides a compound of formula I: or a salt thereof, wherein Y, Z, L, and W have any of the values described in the specification, as well as compositions comprising a compound of formula I or a salt thereof. The compounds are useful as tools for visualizing FtsZ and monitoring cell division in a broad range of Gram-positive and Gram-negative bacterial pathogens of acute clinical importance and for identifying new FtsZ inhibitors.Type: ApplicationFiled: September 21, 2020Publication date: March 25, 2021Applicant: Rutgers, The State University of New JerseyInventors: Daniel S. Pilch, Edgar Ferrer-González, Edmond J. LaVoie
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Patent number: 10836706Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.Type: GrantFiled: February 23, 2017Date of Patent: November 17, 2020Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit Parhi, Gifty A. Blankson, Liping Wang, Xiao Chen, Yongzheng Zhang, Malvika Kaul, Daniel S. Pilch
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Patent number: 10556854Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.Type: GrantFiled: February 23, 2017Date of Patent: February 11, 2020Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit Parhi, Malvika Kaul, Daniel S. Pilch
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Publication number: 20190084919Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.Type: ApplicationFiled: February 23, 2017Publication date: March 21, 2019Applicant: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit Parhi, Malvika Kaul, Daniel S. Pilch
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Publication number: 20190055188Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising compounds of formula I and methods using compounds of formula I.Type: ApplicationFiled: February 23, 2017Publication date: February 21, 2019Inventors: Edmond J. LaVoie, Ajit Parhi, Gifty A. Blankson, Liping Wang, Xiao Chen, Yongzheng Zhang, Malvika Kaul, Daniel S. Pilch
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Publication number: 20180338957Abstract: The invention provides synthetic methods and synthetic intermediates that are useful for preparing the antibacterial compound:Type: ApplicationFiled: August 2, 2018Publication date: November 29, 2018Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, TAXIS PHARMACEUTICALS, INC.Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
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Patent number: 10071082Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.Type: GrantFiled: August 31, 2016Date of Patent: September 11, 2018Assignees: Rutgers, The State University of New Jersey, Taxis Pharmaceuticals, Inc.Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
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Publication number: 20180179225Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.Type: ApplicationFiled: August 3, 2017Publication date: June 28, 2018Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY, TAXIS PHARMACEUTICALS, INC.Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
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Patent number: 9950993Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.Type: GrantFiled: March 11, 2016Date of Patent: April 24, 2018Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit K. Parhi, Malvika Kaul, Daniel S. Pilch
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Patent number: 9926261Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.Type: GrantFiled: March 10, 2016Date of Patent: March 27, 2018Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit K. Parhi, Gifty A. Blankson, Malvika Kaul, Daniel S. Pilch
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Patent number: 9822108Abstract: The invention provides methods of treating a bacterial infection in a mammal comprising administering to the mammal a substituted bicyclic heteroaromatic ring compound of formula I: wherein two of X1 to X8 are N and the remaining of X1 to X8 are CH; or a pharmaceutically acceptable salt thereof, as well as novel compounds of formula I and salts thereof and pharmaceutical compositions comprising a compound of formula I or a pharmaceutically acceptable salt thereof.Type: GrantFiled: January 11, 2013Date of Patent: November 21, 2017Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Malvika Kaul
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Publication number: 20160367531Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.Type: ApplicationFiled: August 31, 2016Publication date: December 22, 2016Applicants: Rutgers, The State University of New Jersey, Taxis Pharmaceuticals, Inc.Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
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Patent number: 9475783Abstract: The invention provides compounds of formula (I): wherein R1-R7 and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.Type: GrantFiled: March 21, 2013Date of Patent: October 25, 2016Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit Parhi, Yongzheng Zhang, Daniel S. Pilch, Malvika Kaul
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Patent number: 9458150Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.Type: GrantFiled: November 7, 2014Date of Patent: October 4, 2016Assignees: Rutgers, The State University of New Jersey, Taxis Pharmaceuticals, Inc.Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
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Publication number: 20160271081Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.Type: ApplicationFiled: March 11, 2016Publication date: September 22, 2016Applicant: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Gifty A. Blankson, Ajit K. Parhi, Malvika Kaul, Daniel S. Pilch
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Publication number: 20160271082Abstract: Disclosed herein are compounds of formula I: and salts thereof. Also disclosed are compositions comprising of compounds of formula I and methods using compounds of formula I.Type: ApplicationFiled: March 10, 2016Publication date: September 22, 2016Applicant: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Ajit K. Parhi, Gifty A. Blankson, Malvika Kaul, Daniel S. Pilch
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Patent number: 9227966Abstract: The invention provides a compound of formula I: or a salt or prodrug thereof, wherein Y, W, Z, Z1, Z2, Z3, Z4, and R1-R12 have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as antibacterial agents.Type: GrantFiled: February 21, 2014Date of Patent: January 5, 2016Assignee: Rutgers, The State University of New JerseyInventors: Edmond J. LaVoie, Daniel S. Pilch, Ajit Parhi, Malvika Kaul
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Publication number: 20150307517Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.Type: ApplicationFiled: May 6, 2015Publication date: October 29, 2015Applicants: TAXIS PHARMACEUTICALS, INC., RUTGERS, THE STATE UNIVERSITY OF NEW JERSEYInventors: Edmond J. LAVOIE, Ajit PARHI, Daniel S. PILCH, Yongzheng ZHANG, Malvika KAUL
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Patent number: 9102617Abstract: The invention provides a compound of formula I: or a salt thereof, wherein R3-R8 and X and Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful as antibacterial agents.Type: GrantFiled: June 24, 2011Date of Patent: August 11, 2015Assignees: Rutgers, The State University of New Jersey, University of Medicine and Dentistry of New JerseyInventors: Edmond J. Lavoie, Ajit Parhi, Daniel S. Pilch
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Publication number: 20150133465Abstract: The invention provides compounds of formula (I): wherein R1-R3, n, and W have any of the values defined in the specification, and salts thereof. The compounds have good solubility and are useful for treating bacterial infections.Type: ApplicationFiled: November 7, 2014Publication date: May 14, 2015Inventors: Edmond J. LaVoie, Ajit Parhi, Daniel S. Pilch, Yongzheng Zhang, Malvika Kaul
