Patents by Inventor Daniel S. Roseman

Daniel S. Roseman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Competition based-detection assays
    Patent number: 9562904
    Abstract: Disclosed herein are methods and kits which are useful for detecting presence of an enzyme and the relative amount of glycan associated with the enzyme in a test sample based upon the enzyme's ability to competitively inhibit the binding of a ligand in such test sample. The present invention provides the ability to evaluate cell culture conditions and optimize the desired glycoform content of recombinantly prepared enzymes.
    Type: Grant
    Filed: June 3, 2015
    Date of Patent: February 7, 2017
    Assignee: Shire Human Genetic Therapies, Inc.
    Inventor: Daniel S. Roseman
  • Enzymatic activity based-detection
    Patent number: 9383359
    Abstract: Disclosed herein are methods and kits which are useful for detecting presence of an enzyme in a test sample based upon the intrinsic enzymatic activity of such test sample. The present invention provides the ability to evaluate cell culture conditions and optimize the desired glycoform content of recombinantly prepared enzymes.
    Type: Grant
    Filed: June 9, 2014
    Date of Patent: July 5, 2016
    Assignee: SHIRE HUMAN GENETIC THERAPIES, INC.
    Inventor: Daniel S. Roseman
  • COMPETITION BASED-DETECTION ASSAYS
    Publication number: 20150338410
    Abstract: Disclosed herein are methods and kits which are useful for detecting presence of an enzyme and the relative amount of glycan associated with the enzyme in a test sample based upon the enzyme's ability to competitively inhibit the binding of a ligand in such test sample. The present invention provides the ability to evaluate cell culture conditions and optimize the desired glycoform content of recombinantly prepared enzymes.
    Type: Application
    Filed: June 3, 2015
    Publication date: November 26, 2015
    Inventor: Daniel S. Roseman
  • Competition-based detection assays
    Patent number: 9075057
    Abstract: Disclosed herein are methods and kits which are useful for detecting presence of an enzyme and the relative amount of glycan associated with the enzyme in a test sample based upon the enzyme's ability to competitively inhibit the binding of a ligand in such test sample. The present invention provides the ability to evaluate cell culture conditions and optimize the desired glycoform content of recombinantly prepared enzymes.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: July 7, 2015
    Assignee: Shire Human Genetic Therapies, Inc.
    Inventor: Daniel S. Roseman
  • ENZYMATIC ACTIVITY BASED-DETECTION
    Publication number: 20140302531
    Abstract: Disclosed herein are methods and kits which are useful for detecting presence of an enzyme in a test sample based upon the intrinsic enzymatic activity of such test sample. The present invention provides the ability to evaluate cell culture conditions and optimize the desired glycoform content of recombinantly prepared enzymes.
    Type: Application
    Filed: June 9, 2014
    Publication date: October 9, 2014
    Applicant: Shire Human Genetic Therapies, Inc.
    Inventor: Daniel S. Roseman
  • COMPETITION-BASED DETECTION ASSAYS
    Publication number: 20140220595
    Abstract: Disclosed herein are methods and kits which are useful for detecting presence of an enzyme and the relative amount of glycan associated with the enzyme in a test sample based upon the enzyme's ability to competitively inhibit the binding of a ligand in such test sample. The present invention provides the ability to evaluate cell culture conditions and optimize the desired glycoform content of recombinantly prepared enzymes.
    Type: Application
    Filed: June 8, 2012
    Publication date: August 7, 2014
    Applicant: Shire Human Genetic Therapies, Inc.
    Inventor: Daniel S. Roseman
  • Enzymatic activity-based detection
    Patent number: 8778622
    Abstract: Disclosed herein are methods and kits which are useful for detecting presence of an enzyme in a test sample based upon the intrinsic enzymatic activity of such test sample. The present invention provides the ability to evaluate cell culture conditions and optimize the desired glycoform content of recombinantly prepared enzymes.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: July 15, 2014
    Assignee: Shire Human Genetic Therapies, Inc.
    Inventor: Daniel S. Roseman
  • ENZYMATIC ACTIVITY-BASED DETECTION
    Publication number: 20120288874
    Abstract: Disclosed herein are methods and kits which are useful for detecting presence of an enzyme in a test sample based upon the intrinsic enzymatic activity of such test sample. The present invention provides the ability to evaluate cell culture conditions and optimize the desired glycoform content of recombinantly prepared enzymes.
    Type: Application
    Filed: November 30, 2010
    Publication date: November 15, 2012
    Inventor: Daniel S. Roseman