Patents by Inventor Daniel S. Treitler

Daniel S. Treitler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDE
    Publication number: 20230271946
    Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-5N-(methyl-d3)pyridazine-3-carboxamide of the formula: Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
    Type: Application
    Filed: April 13, 2023
    Publication date: August 31, 2023
    Inventors: Ke Chen, Joerg Deerberg, Dong Lin, Michael Dummeldinger, Bahar Inankur, Sergei Kolotuchin, Jun Li, Amanda J. Rogers, Victor W. Rosso, Eric M. Simmons, Maxime C.D. Soumeillant, Daniel S. Treitler, Jianji Wang, Bin Zheng, Michael J. Smith, Neil A. Strotman, Steven Tymonko, Tamas Benkovics
  • Process for the preparation of 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-n-(methyl- D3)pyridazine-3-carboxamide
    Patent number: 11649226
    Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: May 16, 2023
    Assignee: Bristol-Myers Squibb Company
    Inventors: Bahar Inankur, Sergei Kolotuchin, Maxime C. D. Soumeillant, Daniel S. Treitler
  • PROCESS FOR THE PREPARATION OF A CYCLIC DINUCLEOTIDE
    Publication number: 20220064205
    Abstract: The invention generally relates to an improved processes for the preparation of a cyclic dinucleotide which is useful as a STING agonist of the following formula (I), involving the use of compounds A and B.
    Type: Application
    Filed: December 3, 2019
    Publication date: March 3, 2022
    Inventors: Michael Anthony Schmidt, Bin Zheng Kendall Park, Benjamin M. Cohen, Amanda J. Rogers, Changxia Yuan Warren, Jason J. Zhu, Chao Hang, Daniel S. Treitler, Adam Josep Freitag, Geoffrey Eugene Purdum, Miao Yu, Melda Sezen Edmonds, Siwei Guo
  • PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDE
    Publication number: 20210107897
    Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
    Type: Application
    Filed: December 22, 2020
    Publication date: April 15, 2021
    Inventors: Ke Chen, Joerg Deerberg, Dong Lin, Michael Dummeldinger, Bahar Inankur, Sergei Kolotuchin, Jun Li, Amanda J. Rogers, Victor W. Rosso, Eric M. Simmons, Maxime C.D. Soumeillant, Daniel S. Treitler, Jianji Wang, Bin Zheng, Michael J. Smith, Neil A. Strotman, Steven Tymonko, Tamas Benkovics
  • Process for the preparation of 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide
    Patent number: 10899745
    Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: [INSERT CHEMICAL STRUCTURE HERE] Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: January 26, 2021
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ke Chen, Joerg Deerberg, Dong Lin, Michael Dummeldinger, Bahar Inankur, Sergei Kolotuchin, Jun Li, Amanda J. Rogers, Victor W. Rosso, Eric M. Simmons, Daniel S. Treitler, Jianji Wang, Michael J. Smith, Tamas Benkovics
  • PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDE
    Publication number: 20200109134
    Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: [INSERT CHEMICAL STRUCTURE HERE] Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
    Type: Application
    Filed: March 29, 2018
    Publication date: April 9, 2020
    Inventors: Ke Chen, Joerg Deerberg, Dong Lin, Michael Dummeldinger, Bahar Inankur, Sergei Kolotuchin, Jun Li, Amanda J. Rogers, Victor W. Rosso, Eric M. Simmons, Maxime C.D. Soumeillant, Daniel S. Treitler, Jianji Wang, Bin Zheng, Michael J. Smith, Neil A. Strotman, Steven Tymonko, Tamas Benkovics
  • UNIQUE HALOGEN-INDUCED CYCLIZATIONS, REAGENTS THEREFOR, AND COMPOUNDS PRODUCED THEREBY
    Publication number: 20140243404
    Abstract: This disclosure is related to halonium compounds useful for cyclization of polyenes, alkenoic acids, and alkenyl alkyl ethers, and halogenation of aromatic compounds. The synthesis of such halonium compounds, compounds made using such halonium compounds, and synthesis of natural compounds, including decalins, using the halonium compounds is also disclosed.
    Type: Application
    Filed: September 13, 2011
    Publication date: August 28, 2014
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Scott Alan Snyder, Daniel S. Treitler, Alexandria P. Brucks, Andreas Gollner, Maria I. Chiriac, Nathan E. Wright, Jason J. Pflueger, Steven P. Breazzano