Patents by Inventor Daniel Salomon

Daniel Salomon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENE EXPRESSION PROFILES ASSOCIATED WITH SUB-CLINICAL KIDNEY TRANSPLANT REJECTION
    Publication number: 20240410007
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
    Type: Application
    Filed: June 24, 2024
    Publication date: December 12, 2024
    Inventors: Daniel Salomon, John Friedewald, Sunil Kurian, Michael M. Abecassis, Steve Head, Phillip Todd Ordoukhanian
  • Gene expression profiles associated with sub-clinical kidney transplant rejection
    Patent number: 12060611
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: August 13, 2024
    Assignees: THE SCRIPPS RESEARCH INSTITUTE, NORTHWESTERN UNIVERSITY
    Inventors: Daniel Salomon, John Friedewald, Sunil Kurian, Michael M. Abecassis, Steve Head, Phillip Ordoukhanian
  • Molecular signatures for distinguishing liver transplant rejections or injuries
    Patent number: 11104951
    Abstract: By a genome-wide gene analysis of expression profiles of known or putative gene sequences in peripheral blood and biopsy samples, the present inventors have identified a consensus set of gene expression-based molecular biomarkers for distinguishing liver transplantation patients who have Acute Rejection (AR), Hepatitis C Virus Recurrence (HCV-R), both AR/HCV-R, or Acute Dysfunction No Rejection (ADNR). These molecular biomarkers are useful for diagnosis, prognosis and monitoring of liver transplantation patients.
    Type: Grant
    Filed: May 22, 2015
    Date of Patent: August 31, 2021
    Assignees: The Scripps Research Institute, Northwestern University
    Inventors: Daniel Salomon, Josh Levitsky, Sunil Kurian, Michael Abecassis
  • Methods and systems for analysis of organ transplantation
    Patent number: 10870888
    Abstract: Disclosed herein are methods of detecting, predicting or monitoring a status or outcome of a transplant in a transplant recipient.
    Type: Grant
    Filed: February 17, 2018
    Date of Patent: December 22, 2020
    Assignees: The Scripps Research Institute, Northwestern University
    Inventors: Daniel Salomon, Sunil M. Kurian, Steven Head, Michael M. Abecassis, John J. Friedewald, Josh Levitsky
  • GENE EXPRESSION PROFILES ASSOCIATED WITH SUB-CLINICAL KIDNEY TRANSPLANT REJECTION
    Publication number: 20200208217
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with subclinical acute rejection (subAR). These genes sets are useful for diagnosis, prognosis, monitoring of subAR.
    Type: Application
    Filed: September 12, 2019
    Publication date: July 2, 2020
    Inventors: Daniel Salomon, John Friedewald, Sunil Kurian, Michael M. Abecassis, Steve Head, Phillip Ordoukhanian
  • METHODS AND SYSTEMS FOR ANALYSIS OF ORGAN TRANSPLANTATION
    Publication number: 20180371546
    Abstract: Disclosed herein are methods of detecting, predicting or monitoring a status or outcome of a transplant in a transplant recipient.
    Type: Application
    Filed: February 17, 2018
    Publication date: December 27, 2018
    Inventors: Daniel Salomon, Sunil M. KURIAN, Steven HEAD, Michael M. ABECASSIS, John J. FRIEDEWALD, Josh LEVITSKY
  • Gene expression profiles associated with chronic allograft nephropathy
    Patent number: 9752191
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with chronic allograft nephropathy and/or interstitial fibrosis and tubular atrophy CAN/IFTA and subtypes thereof. These genes sets are useful for diagnosis, prognosis, monitoring and/or subtyping of CAN/IFTA.
    Type: Grant
    Filed: July 9, 2010
    Date of Patent: September 5, 2017
    Assignee: The Scripps Research Institute
    Inventors: Daniel Salomon, Sunil M. Kurian, Steven R. Head
  • Non-invasive early detection of solid organ transplant rejection by quantitative analysis of mixtures by deep sequencing of HLA gene amplicons using next generation systems
    Patent number: 9752189
    Abstract: The invention is a method of detecting or assessing solid organ graft (transplant) rejection by detecting donor-specific HLA alleles in a blood sample of a graft (transplant) recipient. The invention further comprises a method of detecting the presence of maternal cells in a blood sample of an offspring.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: September 5, 2017
    Assignees: Roche Molecular Systems, Inc., The Scripps Research Institute
    Inventors: Henry Erlich, Bryan Hoglund, Cherie Holcomb, Priscilla Moonsamy, Nick Newton, Melinda Rastrou, Nancy Schoenbrunner, Alison Tsan, Daniel Salomon
  • NON-INVASIVE EARLY DETECTION OF SOLID ORGAN TRANSPLANT REJECTION BY QUANTITATIVE ANALYSIS OF HLA GENE AMPLICONS
    Publication number: 20160017421
    Abstract: The invention is a method of detecting or assessing solid organ graft (transplant) rejection and acute dysfunction—no rejection condition by detecting donor-specific HLA alleles in a blood sample of a graft (transplant) recipient.
    Type: Application
    Filed: November 3, 2014
    Publication date: January 21, 2016
    Inventors: Henry Erlich, Bryan Hoglund, Cherie Holcomb, Priscilla Moonsamy, Nick Newton, Melinda Rastrou, Daniel Salomon, Nancy Shoenbrunner, Alison Tsan
  • NON-INVASIVE EARLY DETECTION OF SOLID ORGAN TRANSPLANT REJECTION BY QUANTITATIVE ANALYSIS OF MIXTURES BY DEEP SEQUENCING OF HLA GENE AMPLICONS USING NEXT GENERATION SYSTEMS
    Publication number: 20140336056
    Abstract: The invention is a method of detecting or assessing solid organ graft (transplant) rejection by detecting donor-specific HLA alleles in a blood sample of a graft (transplant) recipient. The invention further comprises a method of detecting the presence of maternal cells in a blood sample of an offspring.
    Type: Application
    Filed: May 8, 2014
    Publication date: November 13, 2014
    Applicants: Roche Molecular Systems, The Scripps Research Institute
    Inventors: Henry Erlich, Bryan Hoglund, Cherie Holcomb, Priscilla Moonsamy, Nick Newton, Melinda Rastrou, Nancy Schoenbrunner, Alison Tsan, Daniel Salomon
  • GENE EXPRESSION PROFILES ASSOCIATED WITH CHRONIC ALLOGRAFT NEPHROPATHY
    Publication number: 20120178642
    Abstract: By a genome-wide gene analysis of expression profiles of over 50,000 known or putative gene sequences in peripheral blood, the present inventors have identified a consensus set of gene expression-based molecular biomarkers associated with chronic allograft nephropathy and/or interstitial fibrosis and tubular atrophy CAN/IFTA and subtypes thereof. These genes sets are useful for diagnosis, prognosis, monitoring and/or subtyping of CAN/IFTA.
    Type: Application
    Filed: July 9, 2010
    Publication date: July 12, 2012
    Applicant: The Scripps Research Institute
    Inventors: Daniel Salomon, Sunil M. Kurian, Steven R. Head