Abstract: A vehicle includes a controller configured to connect to a network and further configured to receive a feature activation request referencing an owner. The controller is configured to publish an event including the feature activation request on an event network. Each component of a plurality of components of the vehicle is configured to, if the each component is the owner referenced by the feature activation request of the event, execute the feature activation request. The plurality of components may be electronic control units (ECUs). The each component may be configured to execute the feature activation request by activating a feature that is present on the each component prior to receiving the feature activation request by the controller and without reflashing the each component. The each component may publish events for processing by other components in response to the feature activation request.

Abstract: According to one aspect, the present description concerns a target (20) for the production of nuclear particles. The target comprises a shell (24) formed by a surface of revolution and mounted in rotation about an axis of rotation (21) that coincides with an axis of revolution of the shell.

Abstract: An orthopedic surgical instrument or impactor arranged and configured to convert rotational motion of a motor into linear (e.g., reciprocating) motion of an internal hammer to drive an orthopedic implant (e.g., an acetabular cup, a femoral hip implant, an intramedullary nail, etc.) and/or a surgical tool (e.g., a broach, a rasp, a cutting tool, etc.) into a patient's bone. In addition, and/or alternatively, the orthopedic surgical instrument may be reversed to assist with removal of the orthopedical implant and/or surgical tool. In some examples, the orthopedic surgical instrument includes a swashplate and a wobble shaft to convert the rotational motion into linear motion. In addition, and/or alternatively, the orthopedic surgical instrument may be arranged and configured with multiple modes of operation to enable a user to selectively, and independently, adjust the impact energy, frequency, etc.

Abstract: A mobile imaging system or mini C-arm with an increased range of motion is disclosed. The mini C-arm including a mobile base, a C-arm assembly, and an arm assembly for coupling the C-arm assembly and the mobile base. The arm assembly being coupled to the mobile base via a first joint assembly that enables the arm assembly to move relative to the mobile base about first and second axes of rotation. Thus, in use, the first joint assembly enables two degrees of motion—a first vertical pivoting or rotational movement and a second horizontal pivoting or rotational movement. The first joint assembly being coupled to the base via a horizontal axis of rotation that is located at a vertically fixed position so that the horizontal axis of rotation is positioned at a fixed height or distance from the base, and hence a fixed height or distance from the floor.

Abstract: A mobile imaging system or mini C-arm with an increased range of motion is disclosed. The mini C-arm including a mobile base, a C-arm assembly, and an arm assembly for coupling the C-arm assembly and the mobile base. The arm assembly being coupled to the mobile base via a first joint assembly that enables the arm assembly to move relative to the mobile base about first and second axes of rotation. Thus, in use, the first joint assembly enables two degrees of motion—a first vertical pivoting or rotational movement and a second horizontal pivoting or rotational movement. The first joint assembly being coupled to the base via a horizontal axis of rotation that is located at a vertically fixed position so that the horizontal axis of rotation is positioned at a fixed height or distance from the base, and hence a fixed height or distance from the floor.

Abstract: A medical imaging device includes an x-ray source disposed at a first end of an arm, and an x-ray detector disposed at a second end of the arm opposite of the x-ray source. At least one of the x-ray source, the x-ray detector, and a portion of the arm are selectively adjustable with respect to the arm.

Abstract: Provided herein are methods of monitoring for the production of select antibodies in a non-human animal, comprising (a) immunizing a non-human animal with an immunogen; (b) obtaining a blood sample comprising antibody secreting cells (ASCs) from said non-human animal; and (c) individually assaying ASCs present in the blood sample, or a fraction thereof, for the production of select antibodies. Methods of guiding antibody production in a non-human animal for the production of select antibodies are also provided. In exemplary embodiments, the method comprises performing a cycle of (a) to (c), as above, and repeating the cycle when the percentage of ASCs producing select antibodies is below a threshold. In various aspects, the cycle is repeated until the percentage of ASCs producing select antibodies is at or above a threshold. Single cell assays are further provided herein.

Abstract: A medical imaging device includes an x-ray source disposed at a first end of an arm, and an x-ray detector disposed at a second end of the arm opposite of the x-ray source. At least one of the x-ray source, the x-ray detector, and a portion of the arm are selectively adjustable with respect to the arm.

Abstract: A mini C-arm with a movable X-ray source is disclosed. The mini C-arm including a moveable base, a C-arm assembly, and an arm assembly for coupling the C-arm assembly and the base. The C-arm assembly includes a first end, a second end, and a curved intermediate body portion defining an arc length. The source is positioned adjacent to the first end. A detector is positioned at the second end. The source is moveable along the arc length and relative to the detector to enable a plurality of images of the patient's anatomy to be acquired including a first image when the X-ray source is at a first position and a second image when the X-ray source is at a second position. The images being taken without moving the patient's anatomy. The C-arm assembly may include a motor and a belt drive system for moving the source relative to the detector.

Abstract: According to one aspect, the present description concerns a target (20) for the production of nuclear particles. The target comprises a shell (24) formed by a surface of revolution and mounted in rotation about an axis of rotation (21) that coincides with an axis of revolution of the shell.

Abstract: The present disclosure provides methods and compositions for precisely controlling the expression levels of mammalian genes using CRISPRi or CRISPRa and one or more modified sgRNAs. The methods and compositions are useful for, inter alia, titrating the expression of a gene of interest, identifying drug targets and mechanisms of drug resistance, and enabling the analysis of and control over metabolic and signaling pathway fluxes.

Abstract: A medical imaging device includes an x-ray source disposed at a first end of an arm, and an x-ray detector disposed at a second end of the arm opposite of the x-ray source. At least one of the x-ray source, the x-ray detector, and a portion of the arm are selectively adjustable with respect to the arm.

Abstract: A mobile imaging system or mini C-arm with an increased range of motion is disclosed. The mini C-arm including a mobile base, a C-arm assembly, and an arm assembly for coupling the C-arm assembly and the mobile base. The arm assembly being coupled to the mobile base via a first joint assembly that enables the arm assembly to move relative to the mobile base about first and second axes of rotation. Thus, in use, the first joint assembly enables two degrees of motion—a first vertical pivoting or rotational movement and a second horizontal pivoting or rotational movement. The first joint assembly being coupled to the base via a horizontal axis of rotation that is located at a vertically fixed position so that the horizontal axis of rotation is positioned at a fixed height or distance from the base, and hence a fixed height or distance from the floor.

Abstract: A device for measuring the energy of neutrons incident in a first direction is provided. The device comprises a gas between a cathode and an anode, the anode comprising a matrix array of electron detectors, the first direction being orthogonal to the anode-cathode direction.

Abstract: A medical imaging device includes an x-ray source disposed at a first end of an arm, and an x-ray detector disposed at a second end of the arm opposite of the x-ray source. At least one of the x-ray source, the x-ray detector, and a portion of the arm are selectively adjustable with respect to the arm.

Abstract: A device for measuring the energy of neutrons incident in a first direction is provided. The device comprises a gas between a cathode and an anode, the anode comprising a matrix array of electron detectors, the first direction being orthogonal to the anode-cathode direction.

Abstract: A medical imaging device includes an x-ray source disposed at a first end of an arm, and an x-ray detector disposed at a second end of the arm opposite of the x-ray source. At least one of the x-ray source, the x-ray detector, and a portion of the arm are selectively adjustable with respect to the arm.

Abstract: Provided herein are modified Rubisco large subunit proteins and nucleid acids encoding such proteins, as well as photosynthetic organism transformed with said nucleic acids and expressing said proteins. In certain embodiments, photosynthetic organisms containing said modified Rubisco large subunit proteins exhibit increased biomass production.

Abstract: Systems and methods for altering the shape of a reconfigurable surface area are presented. The present systems and methods facilitate efficient and effective interaction with a device or system. In one embodiment, a surface reconfiguration system includes a flexible surface; an elevation unit that creates alterations in the contours of the surface; and an elevation control component that controls adjustments to the elevation unit. Thus, the surface of the device is reconfigurable based on system, application, mode, and/or user needs. Accordingly, the surface can be used to provide input and output functionality. The surface can include touch detection functionality for added input functionality.

Abstract: Systems and methods for altering the shape of a reconfigurable surface area are presented. The present systems and methods facilitate efficient and effective interaction with a device or system. In one embodiment, a surface reconfiguration system includes a flexible surface; an elevation unit that creates alterations in the contours of the surface; and an elevation control component that controls adjustments to the elevation unit. Thus, the surface of the device is reconfigurable based on system, application, mode, and/or user needs. Accordingly, the surface can be used to provide input and output functionality. The surface can include touch detection functionality for added input functionality.