Patents by Inventor Daniel Schwarze
Daniel Schwarze has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10774356Abstract: The invention relates to transaminases and their use. The ATAs according to the invention are particularly useful for catalyzing the conversion of amines to ketones and/or vice versa. Preferably, the transaminase (ATA) according to the invention comprises an amino acid sequence with at least 80% homology to SEQ ID NO:1, wherein the amino acid sequence is engineered compared to SEQ ID NO:1 such that it comprises at least a substitution selected from the group consisting of F255L, F255A, F255C, F255D, F255E, F255G, F255H, F255K, F255M, F255N, F255P, F255Q, F255R, F255S, F255T, F255V, F255W, and F255Y.Type: GrantFiled: June 10, 2016Date of Patent: September 15, 2020Assignee: C-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Rico Czaja, Sally Bayer, Sebastian Bartsch
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Patent number: 10724008Abstract: The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral secondary alcohols.Type: GrantFiled: August 30, 2018Date of Patent: July 28, 2020Assignee: C-LEcta GmbHInventors: Ramona Schmiedel, Andreas Vogel, Sabrina Koepke, Rico Czaja, Claudia Feller, Hedda Merkens, Kamila Rzeznicka, Daniel Schwarze, Thomas Greiner-Stoeffele, Andreas Petri, Marc Struhalla
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Patent number: 10370693Abstract: The invention relates to transaminases that are particularly useful for catalyzing the conversion of amine substrates to ketone products and/or vice versa.Type: GrantFiled: June 10, 2016Date of Patent: August 6, 2019Assignee: C-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Rico Czaja, Sally Bayer, Sebastian Bartsch
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Publication number: 20190078130Abstract: The invention relates to transaminases and their use. The ATAs according to the invention are particularly useful for catalyzing the conversion of amines to ketones and/or vice versa. Preferably, the transaminase (ATA) according to the invention comprises an amino acid sequence with at least 80% homology to SEQ ID NO:1, wherein the amino acid sequence is engineered compared to SEQ ID NO:1 such that it comprises at least a substitution selected from the group consisting of F255L, F255A, F255C, F255D, F255E, F255G, F255H, F255K, F255M, F255N, F255P, F255Q, F255R, F255S, F255T, F255V, F255W, and F255Y.Type: ApplicationFiled: June 10, 2016Publication date: March 14, 2019Applicant: C-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Rico Czaja, Sally Bayer, Sebastian Bartsch
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Publication number: 20190062714Abstract: The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral secondary alcohols.Type: ApplicationFiled: August 30, 2018Publication date: February 28, 2019Applicant: C-LEcta GmbHInventors: Ramona Schmiedel, Andreas Vogel, Sabrina Koepke, Rico Czaja, Claudia Feller, Hedda Merkens, Kamila Rzeznicka, Daniel Schwarze, Thomas Greiner-Stoeffele, Andreas Petri, Marc Struhalla
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Publication number: 20180298354Abstract: The invention relates to transaminases that are particularly useful for catalyzing the conversion of amine substrates to ketone products and/or vice versa.Type: ApplicationFiled: June 10, 2016Publication date: October 18, 2018Applicant: C-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Rico Czaja, Sally Bayer, Sebastian Bartsch
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Patent number: 10093905Abstract: The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral secondary alcohols.Type: GrantFiled: April 17, 2015Date of Patent: October 9, 2018Assignee: C-LEcta GmbHInventors: Ramona Schmiedel, Andreas Vogel, Sabrina Koepke, Rico Czaja, Claudia Feller, Hedda Merkens, Kamila Rzeznicka, Daniel Schwarze, Thomas Greiner-Stoeffele, Andreas Petri, Marc Struhalla
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Publication number: 20170218345Abstract: The invention relates to ketoreductases and the use thereof. The ketoreductases of the invention are particularly useful for enzymatically catalyzing the reduction of ketones to chiral secondary alcohols.Type: ApplicationFiled: April 17, 2015Publication date: August 3, 2017Applicants: C-LEcta GmbH, C-LEcta GmbHInventors: Ramona Schmiedel, Andreas Vogel, Sabrina Koepke, Rico Czaja, Claudia Feller, Hedda Merkens, Kamila Rzeznicka, Daniel Schwarze, Thomas Greiner-Stoeffele, Andreas Petri, Marc Struhalla
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Patent number: 8916364Abstract: The invention relates to a nitrilase having improved activity in the reaction of a nitrile to form the corresponding carboxylic acid, in particular with respect to reacting 2-methylglutaronitrile, 1-(cyanomethyl)cyclohexane-1-carbonitrile, and benzonitrile. The nitrilase according to the invention is related to nitrilase from acidovorax facilis.Type: GrantFiled: October 12, 2011Date of Patent: December 23, 2014Assignee: c-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Thomas Greiner-Stoeffele
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Publication number: 20130288315Abstract: The invention relates to a nitrilase having improved activity in the reaction of a nitrile to form the corresponding carboxylic acid, in particular with respect to reacting 2-methylglutaronitrile, 1-(cyanomethyl)cyclohexane-1-carbonitrile, and benzonitrile. The nitrilase according to the invention is related to nitrilase from acidovorax facilis.Type: ApplicationFiled: October 12, 2011Publication date: October 31, 2013Applicant: c-LEcta GmbHInventors: Andreas Vogel, Daniel Schwarze, Thomas Greiner-Stoeffele
