Patents by Inventor Daniel Scolnick

Daniel Scolnick has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods to enhance sensitivity of cancer cells to mitotic stress
    Patent number: 7176293
    Abstract: An isolated nucleic acid sequence of a mitotic checkpoint gene, chfr, encodes a Chfr protein having a Forkhead-associated domain and a Ring Finger. This protein is required for regulation of the transition of cells from prophase to metaphase during mitosis. The chfr nucleic acid and Chfr polypeptide are useful in diagnosing tumorigenic cells and in screening for drugs which can inhibit the activity of Chfr in a cancer cell, thereby rendering the cell more sensitive to additional anti-tumor therapies.
    Type: Grant
    Filed: June 14, 2000
    Date of Patent: February 13, 2007
    Assignee: The Wistar Institute of Anatomy and Biology
    Inventors: Thanos Halazonetis, Daniel Scolnick