Abstract: A clamp having a first arcuate clamp member pivotally connected to a second arcuate clamp member via a first pivot member 16 located at one end of the clamp members, the clamp members being pivotable between an open configuration in which the free ends of the clamp members are displaced from one another facilitating the insertion of the mating pipe flanges to be clamped, and a closed configuration wherein the free ends of the clamp members contact one another and encircle the mating flanged end connections. Associated with the first arcuate clamp member is an arcuate articulated lever which itself is pivotally attached by a third pivot member linking to member, which is itself pivotally attached by second pivot member to the free end of the first clamp member.

Abstract: A method of processing mixed-material vehicle scrap includes conditioning the mixed-material vehicle scrap and heating the mixed-material vehicle scrap. The mixed-material vehicle scrap comprises a first group of parts and a second group of parts. The first group of parts includes a first alloy and the second group of parts has a substrate of a second alloy and a coating disposed over the substrate. The mixed-material vehicle scrap is conditioned such that an element of the second alloy is diffused into the coating to form a diffused coating. The diffused coating has a melting temperature greater than a melting temperature of the first alloy. The mixed-material vehicle scrap is heated to a temperature above the melting temperature of the first alloy and below the melting temperature of the diffused coating, thereby allowing the second group of parts to separate from the first group of parts.

Abstract: A vehicle seat with an embedded occupancy detector system and manufacturing method for same, and an occupant protection system including an occupancy detector system embedded in a vehicle seat as described herein. Examples include a molded vehicle seat with one or more inserts including an occupant detection system with one or more sensor pads. A gap housing one or more sensor pads of an occupant detection system may be provided between a surface of an insert and a recessed surface of the molded vehicle seat.

Abstract: The present invention relates to epiregulin antibodies, compositions comprising the same, and methods of making and/or using the antibodies and/or compositions thereof for chronic pain disorders such as chronic osteoarthritis pain, or chronic diabetic peripheral neuropathy pain, or chronic low back pain.

Abstract: A hydroponic substrate includes a three-dimensional self-supporting, vertically stable fibrous body having an inner portion including a first fiber density and an outer crust portion including densified fiber having a second fiber density, the second fiber density being different than the first fiber density, the inner portion and the outer crust portion forming horizontal and vertical liquid pathways structured to distribute liquid throughout the body.

Abstract: A server comprises a communications module; a processor coupled with the communications module; and a memory coupled to the processor and storing processor-executable instructions which, when executed by the processor, configure the processor to obtain transfer records identifying value transfers associated with an account of a user, the transfer records including a transfer amount, a transfer date and a transfer descriptor; group the transfer records based on predefined criteria; within at least one group of the transfer records, identify one or more representative transfer records based at least on stored selection criteria; obtain an image associated with at least one of the representative transfer records; and send, via the communications module and to a computing device associated with the user, a transfer record summary interface, the transfer record summary interface including the image associated with the at least one representative transfer record.

Abstract: Provided herein are APP RNAi agents and compositions comprising an APP RNAi agent. Also provided herein are methods of using the APP RNAi agents or compositions comprising an APP RNAi agent in reducing APP expression and/or treating APP associated neurological diseases.

Abstract: This invention deals with water-soluble graft polymers comprising as polymer base a polysaccharide, and as grafted side chains at least one water soluble ethylenically unsaturated monomer, such unsaturated monomer comprising at least one sodium carboxylate unit, being produced by radically initiated polymerization reaction, and further employing during the polymerization at least one organic compound capable of complexing metal ions, preferably iron, containing in its structure at least one carboxyl-group which may be partially or fully present as acid-group or deprotonated in salt-form, their manufacture and uses, for example in laundry or dishwashing, and a method of stabilizing such graft polymers. The graft polymers have a solid content after manufacturing of at least 20% and with at least 70% of the solid content. The aqueous solution of a grafted polymer is the characterized by a Gardner color less than 4.

Abstract: A fluid pumping system may comprise a pump and a fluid line state detector having, a receptacle, at sensor, and an illuminator. The system may further comprise a fluid transfer set including an output line for mating into the receptacle. The system may further comprise a controller in data communication with the fluid line state detector configured to power the illuminator and monitor an output signal of the sensor when the outlet line is in the receptacle to determine a dry tube light intensity value. The controller may be further configured to govern operation of the pump to prime the output line with fluid. The controller may be further configured to power the illuminator, monitor the output signal, and halt operation of the pump when the output signal indicates the light intensity value has dropped below a primed line threshold which is dependent upon the dry tube intensity value.

Abstract: A cocoa composition including cocoa liquor, cocoa powder, or combinations thereof, milk solids, milk solid alternatives, or combinations thereof, a sugar substitute, and a sensory modifier and with reduced bitterness, reduced cooked milk flavor, increased cocoa flavor, and/or increased cream flavor relative to an equivalent composition without the sensory modifier is described herein. The sensory modifier may include a dicaffeoylquinic acid or salt thereof; and one or more compounds selected from the group consisting of monocaffeoylquinic acids, monoferuloylquinic acids, diferuloylquinic acids, monocoumaroylquinic acids, dicoumaroylquinic acids, and salts thereof.

Abstract: The present disclosure provides polymorphs of 3-(2,3,5,6-tetrafluoro-3?-trifluoromethoxy-biphenyl-4-ylcarbamoyl)-thiophene-2-carboxylic acid, and methods of making such polymorphs. The present disclosure further provides pharmaceutical compositions and kits comprising polymorphs of the invention, and methods of treating, preventing, or ameliorating a disease or condition comprising administering a polymorph of the invention.

Abstract: A vehicle seat with an embedded occupancy detector system and manufacturing method for same, and an occupant protection system including an occupancy detector system embedded in a vehicle seat as described herein. Examples include a molded vehicle seat with one or more inserts including an occupant detection system with one or more sensor pads. A gap housing one or more sensor pads of an occupant detection system may be provided between a surface of an insert and a recessed surface of the molded vehicle seat.

Abstract: The present disclosure generally relates to medicament delivery devices such as autoinjectors, and particularly concerns cover structures configured to surround a medicament delivery member at a proximal end of the medicament delivery device.

Abstract: A fiber mat includes natural wood fibers formed into an elongated strip having an upper surface and a lower surface, the upper surface having a first plurality of channels extending into the elongated strip, each of the first plurality of channels having a channel depth being different in a central portion of the mat than in an edge portion of the mat.

Abstract: Compounds for the delivery of progranulin, a progranulin fragment, and/or at least one granulin protein subunit across the blood brain barrier. Compounds for the delivery of progranulin, a progranulin fragment, and/or at least one granulin protein subunit across the blood brain barrier, the compounds including a progranulin domain, a TfR1 binding domain, and optionally an albumin binding domain. Compounds for the delivery of wildtype or unmodified progranulin across the blood brain barrier.

Abstract: An apparatus for securely joining ropes for rope suspension or payload tie down. The apparatus includes a two substantially identical channel assemblies configured having a first bend to form a rope groove on one end and a second bend to form a cam channel on the other end, the cam channel having a rivet hole and a pin therethrough to enable a cam to rotate therein, and an attachment mechanism to secure the channel assemblies back-to-back thereto. By opening the cam of either assembly, a rope may be threaded through the rope grove, then again on the opposite assembly. The rope can be pulled from its end away from the assemblies to tighten prior to closing the cam(s) upon the ropes. The rope can further be secured by continuing to pull after the cam has been closed, or by using an optional tightening mechanism and method.

Abstract: A body weight support system includes a trolley, a powered conductor operatively coupled to a power supply, and a patient attachment mechanism. The trolley can include a drive system, a control system, and a patient support system. The drive system is movably coupled to a support rail. At least a portion of the control system is physically and electrically coupled to the powered conductor. The patient support mechanism is at least temporarily coupled to the patient attachment mechanism. The control system can control at least a portion of the patient support mechanism based at least in part on a force applied to the patient attachment mechanism.

Abstract: A fiber mat includes natural wood fibers formed into an elongated strip having an upper surface and a lower surface, the upper surface having a first plurality of channels extending into the elongated strip, each of the first plurality of channels having a channel depth being different in a central portion of the mat than in an edge portion of the mat.