Abstract: The invention relates to immunogenic glycopeptides derived from pathogenic microorganisms, which can be used for immunization and diagnosing infections dye to such pathogenic microorganisms and also to method for the selection and preparation thereof.

Abstract: A method for diagnosing an infection in a patient likely to be infected with a pathogenic microorganism, comprising the detection of CD4+ T lymphocytes recognizing at least one glycopeptide derived from said pathogenic microorganism, essentially consisting of a glycosylated T epitope, comprising from 14 to 25 amino acids, among which at least one neutral amino acid is bonded to a disaccharide or to a trisaccharide, and at least 15% of said amino acids are prolines, one of the prolines being located in position ?1 to ?4, relative to the position of said neutral amino acid.

Abstract: The invention relates to a method of malting a non-human mammal model comprising: a. implanting, into an immunocompromised non-human mammal host, heterologous nucleated cells previously bound to a biocompatible support, b. controlling non-adaptive defences of the non-human mammal host, c. recovering a non-human mammal model harbouring settled heterologous nucleated cells capable of maintaining, differentiating and growing. The invention also relates to a non-human mammal model which is an immunocompromised non-human mammal host implanted with a support comprising heterologous nucleated cells settled thereon, and which non-adaptive defences are controlled to enable the heterologous nucleated cells of said implanted support to maintain, differentiate and grow.

Abstract: The invention relates to immunogenic glycopeptides derived from pathogenic microorganisms, which can be used for immunization and diagnosing infections dye to such pathogenic microorganisms and also to method for the selection and preparation thereof.